GB1385685A - Cephalosporin derivatives - Google Patents
Cephalosporin derivativesInfo
- Publication number
- GB1385685A GB1385685A GB1056671A GB1056671A GB1385685A GB 1385685 A GB1385685 A GB 1385685A GB 1056671 A GB1056671 A GB 1056671A GB 1056671 A GB1056671 A GB 1056671A GB 1385685 A GB1385685 A GB 1385685A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- cooh
- cells
- formula
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 3
- 229940124587 cephalosporin Drugs 0.000 title abstract 3
- 150000001780 cephalosporins Chemical class 0.000 title abstract 2
- 102000016938 Catalase Human genes 0.000 abstract 2
- 108010053835 Catalase Proteins 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical group CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 1
- 241001480015 Trigonopsis variabilis Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- -1 cephalosporin compounds Chemical class 0.000 abstract 1
- 230000008014 freezing Effects 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 238000010257 thawing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Cephalosporin Compounds (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1056671A GB1385685A (en) | 1971-04-21 | 1971-04-21 | Cephalosporin derivatives |
| US00245258A US3801458A (en) | 1971-04-21 | 1972-04-18 | Process for preparing cephalosporin derivatives |
| BE782393A BE782393A (fr) | 1971-04-21 | 1972-04-20 | Derives de cephalosporine et leur preparation |
| DK193572A DK138122C (da) | 1971-04-21 | 1972-04-20 | Fremgangsmaade og middel til under anvendelse af enzymer fra trigonopsis variabilis at fremstille cephalosporinforbindelser |
| CH586272A CH593336A5 (enExample) | 1971-04-21 | 1972-04-20 | |
| DE19722219454 DE2219454A1 (de) | 1971-04-21 | 1972-04-20 | Cephalosporinderivate |
| AT347972A AT324547B (de) | 1971-04-21 | 1972-04-20 | Verfahren zur herstellung von cephalosporin verbindungen |
| JP3923272A JPS5535118B1 (enExample) | 1971-04-21 | 1972-04-20 | |
| NLAANVRAGE7205314,A NL177130C (nl) | 1971-04-21 | 1972-04-20 | Werkwijze voor het bereiden van een cefalosporine c analoog. |
| FR7213921A FR2133927B1 (enExample) | 1971-04-21 | 1972-04-20 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1056671A GB1385685A (en) | 1971-04-21 | 1971-04-21 | Cephalosporin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1385685A true GB1385685A (en) | 1975-02-26 |
Family
ID=9970217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1056671A Expired GB1385685A (en) | 1971-04-21 | 1971-04-21 | Cephalosporin derivatives |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3801458A (enExample) |
| AT (1) | AT324547B (enExample) |
| BE (1) | BE782393A (enExample) |
| CH (1) | CH593336A5 (enExample) |
| DE (1) | DE2219454A1 (enExample) |
| FR (1) | FR2133927B1 (enExample) |
| GB (1) | GB1385685A (enExample) |
| NL (1) | NL177130C (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002086143A3 (en) * | 2001-04-19 | 2003-01-09 | Bioferma Murcia S A | Enzymatic process for preparing cephalosporin derivatives |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5713280B2 (enExample) * | 1974-03-11 | 1982-03-16 | ||
| CA1093997A (en) * | 1975-12-25 | 1981-01-20 | Shunichi Watanabe | Process of producing 7-methoxy cephalosporins |
| US4242449A (en) * | 1978-02-21 | 1980-12-30 | Yamanouchi Pharmaceutical Co., Ltd. | 7-Methoxy cephalosporins and process of producing them |
| DE3447023A1 (de) * | 1984-12-22 | 1986-06-26 | Hoechst Ag, 6230 Frankfurt | Neue d-aminosaeure-transaminase und ihre verwendung |
| SE8500157D0 (sv) * | 1985-01-11 | 1985-01-11 | Mosbach Klaus | Isolation and partial characterization of a d-amino acid oxidase active against cephalosporin c from the yeast trigonopsis variabilis |
| US5208155A (en) * | 1985-01-11 | 1993-05-04 | Klaus Mosbach | D-amino acid oxidase and method for isolation thereof |
| US4981789A (en) * | 1987-03-18 | 1991-01-01 | Merck & Co., Inc. | One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives |
| US5229274A (en) * | 1989-06-27 | 1993-07-20 | Merck & Co., Inc. | Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus |
| US5104800A (en) * | 1989-06-27 | 1992-04-14 | Merck & Co., Inc. | One-step cephalosporin c amidase enzyme |
| ES2079442T3 (es) * | 1989-07-19 | 1996-01-16 | Lilly Co Eli | Oxidacion enzimatica mejorada de cef c a acido glutaril-7-amino-cefalosporanico. |
| DE4028119C1 (enExample) * | 1990-09-05 | 1991-12-05 | Hoechst Ag, 6230 Frankfurt, De | |
| IT1252308B (it) * | 1990-12-21 | 1995-06-08 | Antibioticos Spa | Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati |
| TW198064B (enExample) * | 1990-12-24 | 1993-01-11 | Hoechst Ag | |
| IT1247964B (it) * | 1991-06-03 | 1995-01-05 | Ministero Dell Uni E Della | Processo per la preparazione enzimatica di derivati cefalosporanici |
| CA2100987C (en) * | 1992-07-27 | 1999-06-15 | Kaoru Furuya | A transformant capable of producing d-amino acid oxidase |
| EP0600247A3 (de) * | 1992-11-05 | 1995-05-10 | Hoechst Ag | Verfahren zur selektiven Desaktivierung von unerwünschten Proteinen in einem Proteingemisch mittels Mikrowelleneinstrahlung. |
| ES2097080B1 (es) * | 1993-03-08 | 1997-11-16 | Asahi Chemical Ind | Procedimiento para la conversion de cefalosporina c en acido glutaril-7-aminocefalosporanico. |
| US5597704A (en) * | 1995-05-01 | 1997-01-28 | Food Industry Research And Development Institute | Bioconversion of cephalosporin C to glutaryl-7-aminocephalosporanic acid |
| IT1286520B1 (it) * | 1996-12-03 | 1998-07-15 | Antibioticos Spa | Procedimento per la preparazione di intermedi utili nella sintesi di cefalosporine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1241655A (en) * | 1967-08-21 | 1971-08-04 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin compounds |
| GB1272769A (en) * | 1968-08-02 | 1972-05-03 | Glaxo Lab Ltd | Improvements in or relating to cephalosporin derivatives |
-
1971
- 1971-04-21 GB GB1056671A patent/GB1385685A/en not_active Expired
-
1972
- 1972-04-18 US US00245258A patent/US3801458A/en not_active Expired - Lifetime
- 1972-04-20 DE DE19722219454 patent/DE2219454A1/de not_active Ceased
- 1972-04-20 NL NLAANVRAGE7205314,A patent/NL177130C/xx not_active IP Right Cessation
- 1972-04-20 FR FR7213921A patent/FR2133927B1/fr not_active Expired
- 1972-04-20 BE BE782393A patent/BE782393A/xx not_active IP Right Cessation
- 1972-04-20 AT AT347972A patent/AT324547B/de not_active IP Right Cessation
- 1972-04-20 CH CH586272A patent/CH593336A5/xx not_active IP Right Cessation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002086143A3 (en) * | 2001-04-19 | 2003-01-09 | Bioferma Murcia S A | Enzymatic process for preparing cephalosporin derivatives |
| WO2002085914A3 (en) * | 2001-04-19 | 2003-02-06 | Bioferma Murcia S A | ENZYMATIC PROCESS FOR PREPARING CEPHALOSPORANIC ACID DERIVATIVES USING α-KETOACID DERIVATIVES |
| US6642020B2 (en) | 2001-04-19 | 2003-11-04 | Bioferma Murcia S.A. | Process for preparing cephalosporin derivatives |
| US6730497B2 (en) | 2001-04-19 | 2004-05-04 | Bioferma Murcia S.A. | Process for preparing cephalosporanic acid derivatives using β-ketoacid derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2133927B1 (enExample) | 1975-10-24 |
| DE2219454A1 (de) | 1972-11-02 |
| US3801458A (en) | 1974-04-02 |
| BE782393A (fr) | 1972-10-20 |
| NL7205314A (enExample) | 1972-10-24 |
| NL177130B (nl) | 1985-03-01 |
| NL177130C (nl) | 1985-08-01 |
| CH593336A5 (enExample) | 1977-11-30 |
| FR2133927A1 (enExample) | 1972-12-01 |
| AT324547B (de) | 1975-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |