GB1382996A - Substituted biphenyls - Google Patents
Substituted biphenylsInfo
- Publication number
- GB1382996A GB1382996A GB793671A GB793671A GB1382996A GB 1382996 A GB1382996 A GB 1382996A GB 793671 A GB793671 A GB 793671A GB 793671 A GB793671 A GB 793671A GB 1382996 A GB1382996 A GB 1382996A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cooh
- corresponding compound
- group
- conhoh
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 235000010290 biphenyl Nutrition 0.000 title abstract 2
- 150000004074 biphenyls Chemical class 0.000 title 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 12
- 150000001875 compounds Chemical class 0.000 abstract 8
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical compound BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000007529 inorganic bases Chemical class 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000004305 biphenyl Substances 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (26)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB793671A GB1382996A (en) | 1971-03-26 | 1971-03-26 | Substituted biphenyls |
| IE284/72A IE36205B1 (en) | 1971-03-26 | 1972-03-07 | Substituted biphenyls |
| IL38957A IL38957A (en) | 1971-03-26 | 1972-03-10 | 2-(substituted biphenylyl)propionic acids |
| ZA721706A ZA721706B (en) | 1971-03-26 | 1972-03-13 | 2-(substituted biphenylyl)propionic acids |
| CA137,098A CA992090A (en) | 1971-03-26 | 1972-03-14 | 2-(substituted biphenylyl) propionic acids |
| AR241057A AR195788A1 (es) | 1971-03-26 | 1972-03-21 | Un procedimiento para la preparacion de acidos 2-(bifenililo sustituido)-propionicos |
| FR7209812A FR2130492B1 (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-21 | |
| BE781054A BE781054A (fr) | 1971-03-26 | 1972-03-22 | Acides 2-(biphenylyl substitue) propioniques |
| AT1065572A AT321288B (de) | 1971-03-26 | 1972-03-23 | Verfahren zur Herstellung von neuen Biphenylylpropionsäuren und ihren Derivaten |
| NL7203920A NL7203920A (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-23 | |
| SE7203796A SE398112B (sv) | 1971-03-26 | 1972-03-23 | Forfarande for framstellning av halogensubstituerade 2-(bifenylyl)-propionsyror |
| AT252672A AT319920B (de) | 1971-03-26 | 1972-03-23 | Verfahren zur Herstellung von neuen Biphenylylpropionsäuren sowie von ihren pharmazeutisch verwendbaren anorganischen und organischen Salzen und ihrer Hydroxamsäure |
| CS1984A CS163799B2 (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-24 | |
| NO1015/72A NO137546C (no) | 1971-03-26 | 1972-03-24 | Analogifremgangsmaate for fremstilling av terapeutisk aktive bifenylpropionsyrer og derivater herav |
| CH311373A CH563331A5 (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-24 | |
| CH311473A CH562190A5 (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-24 | |
| HUBO1359A HU164381B (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-24 | |
| DE19722214561 DE2214561A1 (de) | 1971-03-26 | 1972-03-24 | 2-Substituierte Propionsäuren, Derivate derselben und Verfahren zu ihrer Herstellung |
| BR721721A BR7201721D0 (pt) | 1971-03-26 | 1972-03-24 | Processo para a preparacao de acidos 2-(bifenilil substituidos)-propionicos |
| CS3030*A CS163800B2 (enrdf_load_stackoverflow) | 1971-03-26 | 1972-03-24 | |
| CH444772A CH552552A (fr) | 1971-03-26 | 1972-03-24 | Procede de preparation d'acides 2-(biphenylyl substitues) propioniques. |
| ES401176A ES401176A1 (es) | 1971-03-26 | 1972-03-25 | Procedimiento para la preparacion de nuevos acidos propio- nicos sustituidos y sus derivados. |
| RO7270285A RO66640A (ro) | 1971-03-26 | 1972-03-27 | Procedeu de obtinere a unor acizi propionici de substitutie |
| RO7200072923A RO62846A (fr) | 1971-03-26 | 1972-03-27 | Procede d'obtenir des acides propioniques substitues |
| AR245896A AR195813A1 (es) | 1971-03-26 | 1972-12-28 | Un procedimiento para la preparacion de acidos propionicos sustituidos |
| US05/397,604 US4052514A (en) | 1971-03-26 | 1973-09-14 | Trihalosubstituted biphenylyl propionic acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB793671A GB1382996A (en) | 1971-03-26 | 1971-03-26 | Substituted biphenyls |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1382996A true GB1382996A (en) | 1975-02-05 |
Family
ID=9842634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB793671A Expired GB1382996A (en) | 1971-03-26 | 1971-03-26 | Substituted biphenyls |
Country Status (19)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1437783A (en) * | 1972-09-22 | 1976-06-03 | Boots Co Ltd | 2-substituted biphenylyl acetic acids and derivatives thereof |
| ATA785173A (de) * | 1972-08-17 | 1975-01-15 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen 4-(4-biphenylyl)-4-hydroxy-buttersaeureamiden |
| JPS582934B2 (ja) * | 1974-07-29 | 1983-01-19 | ニツシンセイフン カブシキガイシヤ | ２−（置換アリ−ル）−プロピオン酸の製法 |
| EP0275354B1 (en) * | 1987-01-21 | 1991-10-16 | Sumitomo Chemical Company, Limited | Process for preparing optically active arylacetic acid derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR7047A (enrdf_load_stackoverflow) * | 1904-07-11 |
-
1971
- 1971-03-26 GB GB793671A patent/GB1382996A/en not_active Expired
-
1972
- 1972-03-07 IE IE284/72A patent/IE36205B1/xx unknown
- 1972-03-10 IL IL38957A patent/IL38957A/xx unknown
- 1972-03-13 ZA ZA721706A patent/ZA721706B/xx unknown
- 1972-03-14 CA CA137,098A patent/CA992090A/en not_active Expired
- 1972-03-21 AR AR241057A patent/AR195788A1/es active
- 1972-03-21 FR FR7209812A patent/FR2130492B1/fr not_active Expired
- 1972-03-22 BE BE781054A patent/BE781054A/xx unknown
- 1972-03-23 SE SE7203796A patent/SE398112B/xx unknown
- 1972-03-23 NL NL7203920A patent/NL7203920A/xx unknown
- 1972-03-23 AT AT252672A patent/AT319920B/de not_active IP Right Cessation
- 1972-03-23 AT AT1065572A patent/AT321288B/de not_active IP Right Cessation
- 1972-03-24 DE DE19722214561 patent/DE2214561A1/de active Pending
- 1972-03-24 CH CH311473A patent/CH562190A5/xx not_active IP Right Cessation
- 1972-03-24 CH CH311373A patent/CH563331A5/xx not_active IP Right Cessation
- 1972-03-24 NO NO1015/72A patent/NO137546C/no unknown
- 1972-03-24 BR BR721721A patent/BR7201721D0/pt unknown
- 1972-03-24 HU HUBO1359A patent/HU164381B/hu unknown
- 1972-03-24 CH CH444772A patent/CH552552A/fr not_active IP Right Cessation
- 1972-03-24 CS CS1984A patent/CS163799B2/cs unknown
- 1972-03-24 CS CS3030*A patent/CS163800B2/cs unknown
- 1972-03-25 ES ES401176A patent/ES401176A1/es not_active Expired
- 1972-03-27 RO RO7270285A patent/RO66640A/ro unknown
- 1972-03-27 RO RO7200072923A patent/RO62846A/ro unknown
- 1972-12-28 AR AR245896A patent/AR195813A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| CA992090A (en) | 1976-06-29 |
| IL38957A0 (en) | 1972-05-30 |
| ES401176A1 (es) | 1975-02-01 |
| RO62846A (fr) | 1977-11-15 |
| IE36205L (en) | 1972-09-26 |
| NO137546B (no) | 1977-12-05 |
| RO66640A (ro) | 1981-06-30 |
| NL7203920A (enrdf_load_stackoverflow) | 1972-09-28 |
| AR195788A1 (es) | 1973-11-09 |
| CH562190A5 (enrdf_load_stackoverflow) | 1975-05-30 |
| CS163799B2 (enrdf_load_stackoverflow) | 1975-11-07 |
| ZA721706B (en) | 1972-12-27 |
| AT321288B (de) | 1975-03-25 |
| DE2214561A1 (de) | 1972-10-05 |
| FR2130492A1 (enrdf_load_stackoverflow) | 1972-11-03 |
| BR7201721D0 (pt) | 1973-11-01 |
| CH563331A5 (enrdf_load_stackoverflow) | 1975-06-30 |
| CH552552A (fr) | 1974-08-15 |
| NO137546C (no) | 1978-03-15 |
| SE398112B (sv) | 1977-12-05 |
| BE781054A (fr) | 1972-09-22 |
| AT319920B (de) | 1975-01-10 |
| IL38957A (en) | 1975-08-31 |
| CS163800B2 (enrdf_load_stackoverflow) | 1975-11-07 |
| HU164381B (enrdf_load_stackoverflow) | 1974-02-28 |
| FR2130492B1 (enrdf_load_stackoverflow) | 1975-10-31 |
| IE36205B1 (en) | 1976-09-15 |
| AR195813A1 (es) | 1973-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |