GB1380242A - Benzazepine derivatives and processes for their preparation - Google Patents
Benzazepine derivatives and processes for their preparationInfo
- Publication number
- GB1380242A GB1380242A GB965372A GB965372A GB1380242A GB 1380242 A GB1380242 A GB 1380242A GB 965372 A GB965372 A GB 965372A GB 965372 A GB965372 A GB 965372A GB 1380242 A GB1380242 A GB 1380242A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- group
- bromo
- reaction
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008038 benzoazepines Chemical class 0.000 title abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- 229930192474 thiophene Natural products 0.000 abstract 2
- WMUZDBZPDLHUMW-UHFFFAOYSA-N (2-nitrophenyl)acetic acid Chemical compound OC(=O)CC1=CC=CC=C1[N+]([O-])=O WMUZDBZPDLHUMW-UHFFFAOYSA-N 0.000 abstract 1
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 abstract 1
- XCMISAPCWHTVNG-UHFFFAOYSA-N 3-bromothiophene Chemical compound BrC=1C=CSC=1 XCMISAPCWHTVNG-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
- 150000001879 copper Chemical class 0.000 abstract 1
- -1 ethylenedioxy group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000005415 substituted alkoxy group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7106916A FR2128029B1 (enExample) | 1971-03-01 | 1971-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1380242A true GB1380242A (en) | 1975-01-08 |
Family
ID=9072648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB965372A Expired GB1380242A (en) | 1971-03-01 | 1972-03-01 | Benzazepine derivatives and processes for their preparation |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US3767676A (enExample) |
| JP (1) | JPS554111B1 (enExample) |
| AT (1) | AT315183B (enExample) |
| AU (1) | AU461337B2 (enExample) |
| BE (1) | BE779964A (enExample) |
| CA (1) | CA989826A (enExample) |
| CH (1) | CH550197A (enExample) |
| DD (1) | DD96709A5 (enExample) |
| DE (1) | DE2209891C3 (enExample) |
| DK (1) | DK136868B (enExample) |
| ES (1) | ES400254A1 (enExample) |
| FI (1) | FI52584C (enExample) |
| FR (1) | FR2128029B1 (enExample) |
| GB (1) | GB1380242A (enExample) |
| HU (1) | HU163927B (enExample) |
| IL (1) | IL38794A (enExample) |
| NL (1) | NL7202672A (enExample) |
| SE (1) | SE386679B (enExample) |
| SU (1) | SU434656A3 (enExample) |
| ZA (1) | ZA72972B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808810A (en) * | 2006-02-23 | 2008-02-16 | Novartis Ag | Organic compounds |
-
1971
- 1971-03-01 FR FR7106916A patent/FR2128029B1/fr not_active Expired
-
1972
- 1972-02-15 ZA ZA720972A patent/ZA72972B/xx unknown
- 1972-02-16 CH CH218772A patent/CH550197A/fr not_active IP Right Cessation
- 1972-02-18 IL IL38794A patent/IL38794A/xx unknown
- 1972-02-28 US US00230123A patent/US3767676A/en not_active Expired - Lifetime
- 1972-02-29 SE SE7202534A patent/SE386679B/xx unknown
- 1972-02-29 FI FI720528A patent/FI52584C/fi active
- 1972-02-29 HU HURO646A patent/HU163927B/hu unknown
- 1972-02-29 AU AU39459/72A patent/AU461337B2/en not_active Expired
- 1972-02-29 ES ES400254A patent/ES400254A1/es not_active Expired
- 1972-02-29 DD DD161183A patent/DD96709A5/xx unknown
- 1972-02-29 CA CA135,882A patent/CA989826A/fr not_active Expired
- 1972-02-29 BE BE779964A patent/BE779964A/xx unknown
- 1972-03-01 JP JP2069272A patent/JPS554111B1/ja active Pending
- 1972-03-01 NL NL7202672A patent/NL7202672A/xx not_active Application Discontinuation
- 1972-03-01 SU SU1753758A patent/SU434656A3/ru active
- 1972-03-01 DE DE2209891A patent/DE2209891C3/de not_active Expired
- 1972-03-01 AT AT168672A patent/AT315183B/de active
- 1972-03-01 DK DK93872AA patent/DK136868B/da unknown
- 1972-03-01 GB GB965372A patent/GB1380242A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI52584C (fi) | 1977-10-10 |
| JPS554111B1 (enExample) | 1980-01-29 |
| SE386679B (sv) | 1976-08-16 |
| FR2128029A1 (enExample) | 1972-10-20 |
| DK136868B (da) | 1977-12-05 |
| FI52584B (enExample) | 1977-06-30 |
| AU3945972A (en) | 1973-08-30 |
| ZA72972B (en) | 1973-03-28 |
| AU461337B2 (en) | 1975-05-06 |
| DD96709A5 (enExample) | 1973-04-05 |
| FR2128029B1 (enExample) | 1974-08-02 |
| ES400254A1 (es) | 1974-12-16 |
| US3767676A (en) | 1973-10-23 |
| HU163927B (enExample) | 1973-11-28 |
| AT315183B (de) | 1974-05-10 |
| BE779964A (fr) | 1972-08-29 |
| DK136868C (enExample) | 1978-05-08 |
| IL38794A0 (en) | 1972-04-27 |
| NL7202672A (enExample) | 1972-09-05 |
| DE2209891B2 (de) | 1980-07-24 |
| DE2209891C3 (de) | 1981-04-30 |
| CA989826A (fr) | 1976-05-25 |
| SU434656A3 (ru) | 1974-06-30 |
| DE2209891A1 (de) | 1972-09-07 |
| IL38794A (en) | 1975-05-22 |
| CH550197A (fr) | 1974-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |