GB1379533A - O-substituted oxime derivatives of hydroxyphthalaldehydic acids methods for their preparation and compositions containing them - Google Patents
O-substituted oxime derivatives of hydroxyphthalaldehydic acids methods for their preparation and compositions containing themInfo
- Publication number
- GB1379533A GB1379533A GB2546473A GB2546473A GB1379533A GB 1379533 A GB1379533 A GB 1379533A GB 2546473 A GB2546473 A GB 2546473A GB 2546473 A GB2546473 A GB 2546473A GB 1379533 A GB1379533 A GB 1379533A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxyphthalaldehydic
- preparation
- compositions containing
- oxime derivatives
- substituted oxime
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 oxime derivatives of hydroxyphthalaldehydic acids Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000005632 phthalaldehydic acid Chemical class 0.000 abstract 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 abstract 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25764272A | 1972-05-30 | 1972-05-30 | |
| US352739A US3872113A (en) | 1972-05-30 | 1973-04-19 | Hydroxy- and acetoxy-phthalaldehydric acid, O-(substituted) oximes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1379533A true GB1379533A (en) | 1975-01-02 |
Family
ID=26946093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2546473A Expired GB1379533A (en) | 1972-05-30 | 1973-05-29 | O-substituted oxime derivatives of hydroxyphthalaldehydic acids methods for their preparation and compositions containing them |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3872113A (enExample) |
| JP (1) | JPS5714343B2 (enExample) |
| CA (1) | CA1003829A (enExample) |
| DE (1) | DE2326462A1 (enExample) |
| FR (1) | FR2186256B1 (enExample) |
| GB (1) | GB1379533A (enExample) |
| IE (1) | IE37688B1 (enExample) |
| IL (1) | IL42220A0 (enExample) |
| LU (1) | LU67683A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005082841A1 (en) | 2004-02-24 | 2005-09-09 | Irm Llc | Immunosuppressant compounds and compositions |
| EP1633336A4 (en) * | 2003-05-19 | 2008-10-29 | Irm Llc | IMMUNOSUPPRESSIVE COMPOUNDS AND COMPOSITIONS |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5378662A (en) * | 1976-12-21 | 1978-07-12 | Shin Meiwa Ind Co Ltd | Apparatus for treating sewage |
| US4466973A (en) * | 1983-02-01 | 1984-08-21 | Thomas Rennie | Method of treating nasal and sinus congestion |
| JPS6133836U (ja) * | 1984-07-31 | 1986-03-01 | 吉伸 中村 | 高酸素空気製造装置 |
| PH27460A (en) * | 1989-12-28 | 1993-07-09 | Kumiai Chemical Industry Co | Pyrimidine derivatives and herbicidal composition containing the same |
| DE4030929A1 (de) * | 1990-09-29 | 1992-04-02 | Basf Ag | Benzaldoximetherderivate |
| JPH04334358A (ja) * | 1991-05-02 | 1992-11-20 | Ono Pharmaceut Co Ltd | 縮合ベンゼンオキシ酢酸誘導体 |
| EP0916651B1 (en) * | 1996-04-04 | 2003-10-15 | Sankyo Company, Limited | Phenylalkylcarboxylic acid derivatives |
| DE19700019A1 (de) * | 1997-01-03 | 1998-07-09 | Basf Ag | Substituierte 2-Benzoyl-cyclohexan-1,3-dione |
| PH12013501442B1 (en) | 2011-01-07 | 2018-04-20 | Novartis Ag | Immunosuppressant formulations |
| US11434200B2 (en) | 2017-03-09 | 2022-09-06 | Novartis Ag | Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3577441A (en) * | 1967-03-07 | 1971-05-04 | Warner Lambert Pharmaceutical | Nitro substituted benzofurans |
-
1973
- 1973-04-19 US US352739A patent/US3872113A/en not_active Expired - Lifetime
- 1973-05-08 IL IL42220A patent/IL42220A0/xx unknown
- 1973-05-24 DE DE2326462A patent/DE2326462A1/de not_active Withdrawn
- 1973-05-24 IE IE841/73A patent/IE37688B1/xx unknown
- 1973-05-28 LU LU67683A patent/LU67683A1/xx unknown
- 1973-05-28 CA CA172,487A patent/CA1003829A/en not_active Expired
- 1973-05-29 FR FR7319460A patent/FR2186256B1/fr not_active Expired
- 1973-05-29 GB GB2546473A patent/GB1379533A/en not_active Expired
- 1973-05-30 JP JP5988173A patent/JPS5714343B2/ja not_active Expired
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1633336A4 (en) * | 2003-05-19 | 2008-10-29 | Irm Llc | IMMUNOSUPPRESSIVE COMPOUNDS AND COMPOSITIONS |
| US7939519B2 (en) | 2003-05-19 | 2011-05-10 | Novartis Ag | Immunosuppresant compounds and compositions |
| EP2514743A1 (en) * | 2003-05-19 | 2012-10-24 | Irm Llc | Immunosuppressant Compounds and Compositions |
| EP3138835A1 (en) * | 2003-05-19 | 2017-03-08 | Novartis Ag | Immunosuppressant compounds and compositions |
| EP3272736A1 (en) * | 2003-05-19 | 2018-01-24 | Novartis Ag | Immunosuppressant compounds and compositions |
| WO2005082841A1 (en) | 2004-02-24 | 2005-09-09 | Irm Llc | Immunosuppressant compounds and compositions |
| EP1718604A4 (en) * | 2004-02-24 | 2008-02-13 | Irm Llc | COMPOUNDS AND COMPOSITIONS OF IMMUNOSUPPRESSANTS |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2186256B1 (enExample) | 1976-12-31 |
| JPS4948635A (enExample) | 1974-05-11 |
| CA1003829A (en) | 1977-01-18 |
| IE37688L (en) | 1973-11-30 |
| JPS5714343B2 (enExample) | 1982-03-24 |
| DE2326462A1 (de) | 1973-12-13 |
| IE37688B1 (en) | 1977-09-14 |
| LU67683A1 (enExample) | 1975-03-06 |
| IL42220A0 (en) | 1973-07-30 |
| FR2186256A1 (enExample) | 1974-01-11 |
| US3872113A (en) | 1975-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |