GB1379465A - Cephem-4-carboxylic acids their 1-sulphoxides and methods of prepa ring them - Google Patents

Cephem-4-carboxylic acids their 1-sulphoxides and methods of prepa ring them

Info

Publication number
GB1379465A
GB1379465A GB3214172A GB3214172A GB1379465A GB 1379465 A GB1379465 A GB 1379465A GB 3214172 A GB3214172 A GB 3214172A GB 3214172 A GB3214172 A GB 3214172A GB 1379465 A GB1379465 A GB 1379465A
Authority
GB
United Kingdom
Prior art keywords
cephem
amino
compound
thio
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3214172A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US162703A external-priority patent/US3859282A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1379465A publication Critical patent/GB1379465A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
GB3214172A 1971-07-14 1972-07-10 Cephem-4-carboxylic acids their 1-sulphoxides and methods of prepa ring them Expired GB1379465A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US162703A US3859282A (en) 1971-07-14 1971-07-14 Process for preparing 3-substituted methyl-7-acylamido-7-methoxy-2-cephem-4-carboxylic acid and its esters
US17955971A 1971-09-10 1971-09-10
US20121071A 1971-11-22 1971-11-22
US24427072A 1972-04-14 1972-04-14

Publications (1)

Publication Number Publication Date
GB1379465A true GB1379465A (en) 1975-01-02

Family

ID=27496523

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3214172A Expired GB1379465A (en) 1971-07-14 1972-07-10 Cephem-4-carboxylic acids their 1-sulphoxides and methods of prepa ring them

Country Status (9)

Country Link
AU (1) AU464944B2 (enExample)
BE (1) BE785917A (enExample)
CA (1) CA1014949A (enExample)
CH (1) CH583739A5 (enExample)
DD (2) DD105452A5 (enExample)
DE (1) DE2234479C3 (enExample)
FR (2) FR2154425B1 (enExample)
GB (1) GB1379465A (enExample)
NL (1) NL7208855A (enExample)

Also Published As

Publication number Publication date
AU464944B2 (en) 1975-09-11
DD105452A5 (enExample) 1974-04-20
FR2154425B1 (enExample) 1973-12-07
FR2154425A1 (enExample) 1973-05-11
CH583739A5 (enExample) 1977-01-14
CA1014949A (en) 1977-08-02
FR2162237B1 (enExample) 1974-03-15
FR2162237A1 (enExample) 1973-07-13
AU4420772A (en) 1974-01-10
DE2234479A1 (de) 1973-02-15
DD108542A5 (enExample) 1974-09-20
DE2234479B2 (de) 1975-05-22
BE785917A (fr) 1973-01-08
NL7208855A (enExample) 1973-01-16
DE2234479C3 (de) 1976-01-02

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Legal Events

Date Code Title Description
PS Patent sealed
48S Specification amended (sect. 8/1949)
SPA Amended specification published
PCNP Patent ceased through non-payment of renewal fee