CA1014949A - Process for preparing esters of 3-substituted cephalosporins - Google Patents

Process for preparing esters of 3-substituted cephalosporins

Info

Publication number
CA1014949A
CA1014949A CA145,854A CA145854A CA1014949A CA 1014949 A CA1014949 A CA 1014949A CA 145854 A CA145854 A CA 145854A CA 1014949 A CA1014949 A CA 1014949A
Authority
CA
Canada
Prior art keywords
preparing esters
substituted cephalosporins
cephalosporins
substituted
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA145,854A
Other versions
CA145854S (en
Inventor
Seemon H. Pines
Sandor Karady
Meyer Sletzinger
Theresa Y. Cheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US162703A external-priority patent/US3859282A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1014949A publication Critical patent/CA1014949A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA145,854A 1971-07-14 1972-06-27 Process for preparing esters of 3-substituted cephalosporins Expired CA1014949A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US162703A US3859282A (en) 1971-07-14 1971-07-14 Process for preparing 3-substituted methyl-7-acylamido-7-methoxy-2-cephem-4-carboxylic acid and its esters
US17955971A 1971-09-10 1971-09-10
US20121071A 1971-11-22 1971-11-22
US24427072A 1972-04-14 1972-04-14

Publications (1)

Publication Number Publication Date
CA1014949A true CA1014949A (en) 1977-08-02

Family

ID=27496523

Family Applications (1)

Application Number Title Priority Date Filing Date
CA145,854A Expired CA1014949A (en) 1971-07-14 1972-06-27 Process for preparing esters of 3-substituted cephalosporins

Country Status (9)

Country Link
AU (1) AU464944B2 (en)
BE (1) BE785917A (en)
CA (1) CA1014949A (en)
CH (1) CH583739A5 (en)
DD (2) DD108542A5 (en)
DE (1) DE2234479C3 (en)
FR (2) FR2154425B1 (en)
GB (1) GB1379465A (en)
NL (1) NL7208855A (en)

Also Published As

Publication number Publication date
DE2234479B2 (en) 1975-05-22
BE785917A (en) 1973-01-08
FR2162237A1 (en) 1973-07-13
CH583739A5 (en) 1977-01-14
NL7208855A (en) 1973-01-16
FR2154425A1 (en) 1973-05-11
GB1379465A (en) 1975-01-02
DE2234479C3 (en) 1976-01-02
FR2154425B1 (en) 1973-12-07
AU4420772A (en) 1974-01-10
DD108542A5 (en) 1974-09-20
DD105452A5 (en) 1974-04-20
FR2162237B1 (en) 1974-03-15
DE2234479A1 (en) 1973-02-15
AU464944B2 (en) 1975-09-11

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