GB1371650A - Analgesic derivatives of the series of sulphur-containing arylamines - Google Patents
Analgesic derivatives of the series of sulphur-containing arylaminesInfo
- Publication number
- GB1371650A GB1371650A GB4424171A GB4424171A GB1371650A GB 1371650 A GB1371650 A GB 1371650A GB 4424171 A GB4424171 A GB 4424171A GB 4424171 A GB4424171 A GB 4424171A GB 1371650 A GB1371650 A GB 1371650A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aryl
- group
- sulphur
- compounds
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical class [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title abstract 2
- 239000005864 Sulphur Substances 0.000 title abstract 2
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 150000004982 aromatic amines Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004174 2-benzimidazolyl group Chemical group [H]N1C(*)=NC2=C([H])C([H])=C([H])C([H])=C12 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000003106 haloaryl group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE788805D BE788805A (fr) | 1971-09-22 | Nouveaux derives antalgiques de la serie des arylamines soufrees | |
| GB4424171A GB1371650A (en) | 1971-09-22 | 1971-09-22 | Analgesic derivatives of the series of sulphur-containing arylamines |
| FR7233005A FR2154528B1 (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-18 | |
| IL40393A IL40393A0 (en) | 1971-09-22 | 1972-09-20 | Sulphone and sulphoxide derivatives of arylamines,their preparation and pharmaceutical compositions containing them |
| CA152,193A CA996129A (en) | 1971-09-22 | 1972-09-20 | Analgesic derivatives of the series of sulphur-containing arylamines |
| CH111274A CH565757A5 (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-21 | |
| DE2246429A DE2246429C3 (de) | 1971-09-22 | 1972-09-21 | 2-Phenylsulfinyl-Verbindungen und Analgetika, welche diese Verbindungen enthalten |
| CH1382272A CH566308A5 (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-21 | |
| JP47094643A JPS5755718B2 (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-22 | |
| IN1482/72A IN137842B (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-22 | |
| ES406929A ES406929A1 (es) | 1971-09-22 | 1972-09-22 | Procedimiento para la obtencion de compuestos s-oxidos de aril-mercaptanos aminados. |
| NL7212829A NL7212829A (enrdf_load_stackoverflow) | 1971-09-22 | 1972-09-22 | |
| AR244227A AR202378A1 (es) | 1971-09-22 | 1972-09-22 | Procedimiento para la obtencion de clorhidrato de n-(2-fenilsulfonil)-etilmorfolina |
| AU46984/72A AU472048B2 (en) | 1971-09-22 | 1972-09-22 | New analgesic derivatives ofthe series of sulphur-containing arylamines |
| AR248332A AR198415A1 (es) | 1971-09-22 | 1973-05-31 | Procedimiento para la obtencion de compuestos s-oxidos de arilmercaptanos aminados |
| ES436363A ES436363A1 (es) | 1971-09-22 | 1975-04-07 | Procedimiento para obtencion de compuestos s-oxidos de aril-mercaptanos aminados. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4424171A GB1371650A (en) | 1971-09-22 | 1971-09-22 | Analgesic derivatives of the series of sulphur-containing arylamines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1371650A true GB1371650A (en) | 1974-10-23 |
Family
ID=10432415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4424171A Expired GB1371650A (en) | 1971-09-22 | 1971-09-22 | Analgesic derivatives of the series of sulphur-containing arylamines |
Country Status (13)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4134996A (en) * | 1976-08-16 | 1979-01-16 | The Dow Chemical Company | Method for inhibiting adp-induced platelet aggregation using phenylthioalkylamines |
| EP0174717B1 (en) * | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2285859A1 (fr) * | 1974-09-30 | 1976-04-23 | Lafon Labor | Phenylsulfinyl-amidines et derives |
| FR2432316A1 (fr) * | 1978-08-02 | 1980-02-29 | Choay Sa | Nouveaux medicaments contenant, a titre de substance active, des composes de type benzenesulfone, nouveaux composes de ce type et procede pour leur preparation |
| JPS5739044Y2 (enrdf_load_stackoverflow) * | 1978-08-21 | 1982-08-27 | ||
| FR2447909A1 (fr) * | 1979-01-31 | 1980-08-29 | Choay Sa | Nouveaux composes de type benzenesulfone et procede pour leur preparation |
| JPS5964720U (ja) * | 1982-10-22 | 1984-04-28 | 日本軽金属株式会社 | 液体容器 |
| AR243167A1 (es) | 1985-08-24 | 1993-07-30 | Hoechst Ag | Procedimiento para la preparacion de toluidinas sustituidas. |
| JP2933739B2 (ja) * | 1990-04-09 | 1999-08-16 | 明治製菓株式会社 | チアゾールまたはイミダゾール誘導体および抗潰瘍剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD70880A (enrdf_load_stackoverflow) * | ||||
| FR2100668A1 (en) * | 1971-05-19 | 1972-03-24 | Sumitomo Chemical Co | Pharmacol-active heterocyclic cpds |
| JPS4946312A (enrdf_load_stackoverflow) * | 1972-09-05 | 1974-05-02 |
-
0
- BE BE788805D patent/BE788805A/xx not_active IP Right Cessation
-
1971
- 1971-09-22 GB GB4424171A patent/GB1371650A/en not_active Expired
-
1972
- 1972-09-18 FR FR7233005A patent/FR2154528B1/fr not_active Expired
- 1972-09-20 IL IL40393A patent/IL40393A0/xx unknown
- 1972-09-20 CA CA152,193A patent/CA996129A/en not_active Expired
- 1972-09-21 CH CH1382272A patent/CH566308A5/xx not_active IP Right Cessation
- 1972-09-21 CH CH111274A patent/CH565757A5/xx not_active IP Right Cessation
- 1972-09-21 DE DE2246429A patent/DE2246429C3/de not_active Expired
- 1972-09-22 JP JP47094643A patent/JPS5755718B2/ja not_active Expired
- 1972-09-22 IN IN1482/72A patent/IN137842B/en unknown
- 1972-09-22 AU AU46984/72A patent/AU472048B2/en not_active Expired
- 1972-09-22 ES ES406929A patent/ES406929A1/es not_active Expired
- 1972-09-22 NL NL7212829A patent/NL7212829A/xx not_active Application Discontinuation
- 1972-09-22 AR AR244227A patent/AR202378A1/es active
-
1973
- 1973-05-31 AR AR248332A patent/AR198415A1/es active
-
1975
- 1975-04-07 ES ES436363A patent/ES436363A1/es not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4134996A (en) * | 1976-08-16 | 1979-01-16 | The Dow Chemical Company | Method for inhibiting adp-induced platelet aggregation using phenylthioalkylamines |
| US4141983A (en) * | 1976-08-16 | 1979-02-27 | The Dow Chemical Company | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines |
| EP0174717B1 (en) * | 1984-07-06 | 1992-01-22 | FISONS plc | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| AU472048B2 (en) | 1976-05-13 |
| CH565757A5 (enrdf_load_stackoverflow) | 1975-08-29 |
| AR198415A1 (es) | 1974-06-21 |
| CH566308A5 (enrdf_load_stackoverflow) | 1975-09-15 |
| CA996129A (en) | 1976-08-31 |
| JPS5755718B2 (enrdf_load_stackoverflow) | 1982-11-25 |
| FR2154528A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| DE2246429A1 (de) | 1973-03-29 |
| NL7212829A (enrdf_load_stackoverflow) | 1973-03-26 |
| DE2246429C3 (de) | 1982-05-19 |
| ES406929A1 (es) | 1976-02-01 |
| AR202378A1 (es) | 1975-06-06 |
| FR2154528B1 (enrdf_load_stackoverflow) | 1975-10-17 |
| AU4698472A (en) | 1974-03-28 |
| IL40393A0 (en) | 1972-11-28 |
| DE2246429B2 (de) | 1981-07-02 |
| JPS4836147A (enrdf_load_stackoverflow) | 1973-05-28 |
| BE788805A (fr) | 1973-01-02 |
| ES436363A1 (es) | 1977-01-01 |
| IN137842B (enrdf_load_stackoverflow) | 1975-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLE | Entries relating assignments, transmissions, licences in the register of patents | ||
| 435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
| PCNP | Patent ceased through non-payment of renewal fee |