GB1369580A - Tricyclic diphenylamine derivatives - Google Patents
Tricyclic diphenylamine derivativesInfo
- Publication number
- GB1369580A GB1369580A GB3843173A GB3843173A GB1369580A GB 1369580 A GB1369580 A GB 1369580A GB 3843173 A GB3843173 A GB 3843173A GB 3843173 A GB3843173 A GB 3843173A GB 1369580 A GB1369580 A GB 1369580A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- aug
- reacting
- compound
- direct link
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DMBHHRLKUKUOEG-UHFFFAOYSA-N diphenylamine Chemical class C=1C=CC=CC=1NC1=CC=CC=C1 DMBHHRLKUKUOEG-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000000609 carbazolyl group Chemical class C1(=CC=CC=2C3=CC=CC=C3NC12)* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 150000002990 phenothiazines Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 210000002820 sympathetic nervous system Anatomy 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722240599 DE2240599C3 (de) | 1972-08-18 | Carbazol-Derivate, Verfahren zu deren Herstellung und Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1369580A true GB1369580A (en) | 1974-10-09 |
Family
ID=5853874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3843173A Expired GB1369580A (en) | 1972-08-18 | 1973-08-14 | Tricyclic diphenylamine derivatives |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5821624B2 (enrdf_load_html_response) |
| AT (2) | AT326679B (enrdf_load_html_response) |
| BE (1) | BE882929A (enrdf_load_html_response) |
| CH (2) | CH598216A5 (enrdf_load_html_response) |
| FR (1) | FR2196165B1 (enrdf_load_html_response) |
| GB (1) | GB1369580A (enrdf_load_html_response) |
| HK (1) | HK6978A (enrdf_load_html_response) |
| KE (1) | KE2814A (enrdf_load_html_response) |
| MY (1) | MY7800171A (enrdf_load_html_response) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4697022A (en) * | 1983-05-26 | 1987-09-29 | Boehringer Mannheim Gmbh | Process for the preparation of optically-active carbazole derivatives, new R- and S-carbazole derivatives and pharmaceutical compositions containing these compounds |
| US4760085A (en) * | 1983-01-13 | 1988-07-26 | Boehringer Mannheim Gmbh | Use of D,L-and D-carazolol as anti-glaucoma agent |
| RU2204551C2 (ru) * | 1997-11-24 | 2003-05-20 | Эгиш Дьёдьсердьяр Рт. | Способ получения 4-гидрокси-9h-карбазола |
| WO2005115981A3 (en) * | 2004-04-22 | 2006-01-19 | Usv Ltd | A process for the preparation of 1-(9h-carbazol-4-yloxy)-3-2-(-methoxyphenoxy)-ethyl amino-propan-2-ol |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56166172A (en) * | 1980-05-24 | 1981-12-21 | Yasuo Kikukawa | Preparation of alkylindoles |
| FR2516512A1 (fr) * | 1981-11-19 | 1983-05-20 | Corbiere Jerome | Nouveaux derives pyridoindoliques, leur procede de preparation et les compositions pharmaceutiques en contenant |
-
1973
- 1973-08-14 GB GB3843173A patent/GB1369580A/en not_active Expired
- 1973-08-15 CH CH735276A patent/CH598216A5/xx not_active IP Right Cessation
- 1973-08-15 CH CH1177073A patent/CH598215A5/xx not_active IP Right Cessation
- 1973-08-17 FR FR7330003A patent/FR2196165B1/fr not_active Expired
- 1973-08-17 AT AT1014374A patent/AT326679B/de not_active IP Right Cessation
- 1973-08-17 AT AT721373A patent/AT326677B/de not_active IP Right Cessation
- 1973-08-18 JP JP48092853A patent/JPS5821624B2/ja not_active Expired
-
1978
- 1978-01-20 KE KE2814A patent/KE2814A/xx unknown
- 1978-02-02 HK HK69/78A patent/HK6978A/xx unknown
- 1978-12-30 MY MY171/78A patent/MY7800171A/xx unknown
-
1980
- 1980-04-23 BE BE0/200337A patent/BE882929A/fr not_active IP Right Cessation
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4760085A (en) * | 1983-01-13 | 1988-07-26 | Boehringer Mannheim Gmbh | Use of D,L-and D-carazolol as anti-glaucoma agent |
| US4697022A (en) * | 1983-05-26 | 1987-09-29 | Boehringer Mannheim Gmbh | Process for the preparation of optically-active carbazole derivatives, new R- and S-carbazole derivatives and pharmaceutical compositions containing these compounds |
| US4824963A (en) * | 1983-05-26 | 1989-04-25 | Boehringer Mannheim Gmbh | Process for the preparation of optically-active carbazole derivatives |
| RU2204551C2 (ru) * | 1997-11-24 | 2003-05-20 | Эгиш Дьёдьсердьяр Рт. | Способ получения 4-гидрокси-9h-карбазола |
| WO2005115981A3 (en) * | 2004-04-22 | 2006-01-19 | Usv Ltd | A process for the preparation of 1-(9h-carbazol-4-yloxy)-3-2-(-methoxyphenoxy)-ethyl amino-propan-2-ol |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5821624B2 (ja) | 1983-05-02 |
| ATA721373A (de) | 1975-03-15 |
| FR2196165B1 (enrdf_load_html_response) | 1977-01-28 |
| MY7800171A (en) | 1978-12-31 |
| JPS4956973A (enrdf_load_html_response) | 1974-06-03 |
| FR2196165A1 (enrdf_load_html_response) | 1974-03-15 |
| AT326679B (de) | 1975-12-29 |
| DE2240599A1 (de) | 1974-02-28 |
| CH598216A5 (enrdf_load_html_response) | 1978-04-28 |
| CH598215A5 (enrdf_load_html_response) | 1978-04-28 |
| AT326677B (de) | 1975-12-29 |
| KE2814A (en) | 1978-02-24 |
| DE2240599B2 (de) | 1975-10-16 |
| HK6978A (en) | 1978-02-10 |
| BE882929A (fr) | 1980-10-23 |
| ATA1014374A (de) | 1975-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930813 |