GB1368525A - N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation - Google Patents
N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparationInfo
- Publication number
- GB1368525A GB1368525A GB4743672A GB4743672A GB1368525A GB 1368525 A GB1368525 A GB 1368525A GB 4743672 A GB4743672 A GB 4743672A GB 4743672 A GB4743672 A GB 4743672A GB 1368525 A GB1368525 A GB 1368525A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- pyrrolidylmethyl
- biguanides
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940123208 Biguanide Drugs 0.000 title abstract 2
- 150000004283 biguanides Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002490 anilino group Chemical class [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- VMPYTOIPVPQDNX-UHFFFAOYSA-N pyrrolidin-1-ylmethanamine Chemical compound NCN1CCCC1 VMPYTOIPVPQDNX-UHFFFAOYSA-N 0.000 abstract 1
- 235000010288 sodium nitrite Nutrition 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7137412A FR2156427B1 (enrdf_load_stackoverflow) | 1971-10-18 | 1971-10-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1368525A true GB1368525A (en) | 1974-09-25 |
Family
ID=9084549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4743672A Expired GB1368525A (en) | 1971-10-18 | 1972-10-13 | N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE790130A (enrdf_load_stackoverflow) |
| CH (1) | CH544088A (enrdf_load_stackoverflow) |
| ES (1) | ES407633A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2156427B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1368525A (enrdf_load_stackoverflow) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6786M (enrdf_load_stackoverflow) * | 1967-08-10 | 1969-03-17 |
-
0
- BE BE790130D patent/BE790130A/xx not_active IP Right Cessation
-
1971
- 1971-10-18 FR FR7137412A patent/FR2156427B1/fr not_active Expired
-
1972
- 1972-09-14 ES ES407633A patent/ES407633A1/es not_active Expired
- 1972-10-13 GB GB4743672A patent/GB1368525A/en not_active Expired
- 1972-10-17 CH CH1515272A patent/CH544088A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE790130A (fr) | 1973-04-16 |
| FR2156427B1 (enrdf_load_stackoverflow) | 1974-10-18 |
| CH544088A (fr) | 1973-11-15 |
| DE2250856B2 (de) | 1976-01-15 |
| FR2156427A1 (enrdf_load_stackoverflow) | 1973-06-01 |
| DE2250856A1 (de) | 1973-04-26 |
| ES407633A1 (es) | 1975-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |