GB1365437A - Process for the preparation of 3- /3beta 17beta-dihydroxyandrost-5- en-17alpha-yl/ propionic acid ypsilon-lactone and intermediates formed therein - Google Patents
Process for the preparation of 3- /3beta 17beta-dihydroxyandrost-5- en-17alpha-yl/ propionic acid ypsilon-lactone and intermediates formed thereinInfo
- Publication number
- GB1365437A GB1365437A GB3579372A GB3579372A GB1365437A GB 1365437 A GB1365437 A GB 1365437A GB 3579372 A GB3579372 A GB 3579372A GB 3579372 A GB3579372 A GB 3579372A GB 1365437 A GB1365437 A GB 1365437A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dihydroxyandrost
- ypsilon
- 17alpha
- 17beta
- 3beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title 2
- 239000000543 intermediate Substances 0.000 title 1
- 235000019260 propionic acid Nutrition 0.000 title 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- QDWJUBJKEHXSMT-UHFFFAOYSA-N boranylidynenickel Chemical compound [Ni]#B QDWJUBJKEHXSMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- LJAOOBNHPFKCDR-UHFFFAOYSA-K chromium(3+) trichloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].[Cl-].[Cl-].[Cr+3] LJAOOBNHPFKCDR-UHFFFAOYSA-K 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052759 nickel Inorganic materials 0.000 abstract 1
- LAIZPRYFQUWUBN-UHFFFAOYSA-L nickel chloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].[Cl-].[Ni+2] LAIZPRYFQUWUBN-UHFFFAOYSA-L 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16987671A | 1971-08-06 | 1971-08-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1365437A true GB1365437A (en) | 1974-09-04 |
Family
ID=22617580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3579372A Expired GB1365437A (en) | 1971-08-06 | 1972-08-01 | Process for the preparation of 3- /3beta 17beta-dihydroxyandrost-5- en-17alpha-yl/ propionic acid ypsilon-lactone and intermediates formed therein |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3738983A (enExample) |
| DE (1) | DE2238220A1 (enExample) |
| FR (1) | FR2157787B1 (enExample) |
| GB (1) | GB1365437A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4192802A (en) * | 1976-06-09 | 1980-03-11 | Ciba-Geigy Corporation | Process for the manufacture of steroid carboxylic acid lactones |
| DE2632677A1 (de) * | 1976-07-16 | 1978-01-26 | Schering Ag | Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung |
| US4057542A (en) * | 1976-08-30 | 1977-11-08 | G. D. Searle & Co. | Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone |
| JPS5842879B2 (ja) * | 1979-05-14 | 1983-09-22 | 三菱化学株式会社 | ステロイドカルボン酸塩の製造法 |
| RU2163606C1 (ru) * | 1999-12-08 | 2001-02-27 | Андрюшина Валентина Александровна | СПОСОБ ПОЛУЧЕНИЯ γ-ЛАКТОНА 3(7α-АЦЕТИЛТИО-17β-ГИДРОКСИ-3-ОКСОАНДРОСТ-4-ЕН-17α-ИЛ)ПРОПИОНОВОЙ КИСЛОТЫ |
-
1971
- 1971-08-06 US US00169876A patent/US3738983A/en not_active Expired - Lifetime
-
1972
- 1972-08-01 GB GB3579372A patent/GB1365437A/en not_active Expired
- 1972-08-03 DE DE2238220A patent/DE2238220A1/de not_active Withdrawn
- 1972-08-07 FR FR7228445A patent/FR2157787B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3738983A (en) | 1973-06-12 |
| FR2157787A1 (enExample) | 1973-06-08 |
| FR2157787B1 (enExample) | 1976-05-21 |
| DE2238220A1 (de) | 1973-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |