GB1364806A - Benzofuran and benzothiophene derivatives - Google Patents
Benzofuran and benzothiophene derivativesInfo
- Publication number
- GB1364806A GB1364806A GB1387772A GB1387772A GB1364806A GB 1364806 A GB1364806 A GB 1364806A GB 1387772 A GB1387772 A GB 1387772A GB 1387772 A GB1387772 A GB 1387772A GB 1364806 A GB1364806 A GB 1364806A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- amino
- compound
- hydrogen
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 title 2
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- 150000001875 compounds Chemical class 0.000 abstract 10
- -1 cyano, carbamoyl Chemical group 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000003356 anti-rheumatic effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001733 carboxylic acid esters Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000001924 cycloalkanes Chemical class 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- 150000002240 furans Chemical class 0.000 abstract 1
- 230000002140 halogenating effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000007127 saponification reaction Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
- 150000003577 thiophenes Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12857071A | 1971-03-26 | 1971-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1364806A true GB1364806A (en) | 1974-08-29 |
Family
ID=22435954
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1387772A Expired GB1364806A (en) | 1971-03-26 | 1972-03-24 | Benzofuran and benzothiophene derivatives |
| GB5123373A Expired GB1364807A (en) | 1971-03-26 | 1972-03-24 | Phenoxy and phenylthio compounds |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5123373A Expired GB1364807A (en) | 1971-03-26 | 1972-03-24 | Phenoxy and phenylthio compounds |
Country Status (17)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ168896A3 (en) * | 1995-06-27 | 1997-01-15 | Egyt Gyogyszervegyeszeti Gyar | Oxaindene derivatives and process for preparing thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7008628A (enrdf_load_stackoverflow) * | 1969-06-25 | 1970-12-29 |
-
1972
- 1972-03-09 CH CH350472A patent/CH574433A5/xx not_active IP Right Cessation
- 1972-03-09 ZA ZA721612A patent/ZA721612B/xx unknown
- 1972-03-20 IL IL39036A patent/IL39036A/en unknown
- 1972-03-20 IE IE2067/74A patent/IE36187B1/xx unknown
- 1972-03-20 IE IE354/72A patent/IE36186B1/xx unknown
- 1972-03-21 AU AU40245/72A patent/AU463471B2/en not_active Expired
- 1972-03-22 CA CA137,759A patent/CA988529A/en not_active Expired
- 1972-03-23 HU HUHO1463A patent/HU164250B/hu unknown
- 1972-03-24 GB GB1387772A patent/GB1364806A/en not_active Expired
- 1972-03-24 SE SE7203902A patent/SE385704B/xx unknown
- 1972-03-24 NL NL7203979A patent/NL7203979A/xx not_active Application Discontinuation
- 1972-03-24 AT AT229773A patent/AT319227B/de not_active IP Right Cessation
- 1972-03-24 DE DE19722214501 patent/DE2214501A1/de active Pending
- 1972-03-24 AT AT257972A patent/AT313272B/de not_active IP Right Cessation
- 1972-03-24 DK DK145472AA patent/DK130345B/da unknown
- 1972-03-24 FR FR7210383A patent/FR2130655B1/fr not_active Expired
- 1972-03-24 GB GB5123373A patent/GB1364807A/en not_active Expired
- 1972-03-24 BE BE781176A patent/BE781176A/xx unknown
- 1972-03-25 ES ES401162A patent/ES401162A1/es not_active Expired
- 1972-11-23 AR AR245290A patent/AR192514A1/es active
- 1972-11-24 AR AR245289A patent/AR194407A1/es active
- 1972-11-24 AR AR245291A patent/AR192515A1/es active
-
1974
- 1974-12-27 SE SE7416328A patent/SE7416328L/xx unknown
-
1975
- 1975-03-11 IL IL46790A patent/IL46790A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK130345C (enrdf_load_stackoverflow) | 1975-07-07 |
| AR192515A1 (es) | 1973-02-21 |
| DK130345B (da) | 1975-02-10 |
| AU4024572A (en) | 1972-03-21 |
| ZA721612B (en) | 1972-11-29 |
| AT313272B (de) | 1974-02-11 |
| FR2130655A1 (enrdf_load_stackoverflow) | 1972-11-03 |
| IL46790A (en) | 1976-05-31 |
| AT319227B (de) | 1974-12-10 |
| AR194407A1 (es) | 1973-07-13 |
| ES401162A1 (es) | 1975-02-01 |
| IL39036A (en) | 1976-05-31 |
| BE781176A (fr) | 1972-09-25 |
| AR192514A1 (es) | 1973-02-21 |
| SE385704B (sv) | 1976-07-19 |
| GB1364807A (en) | 1974-08-29 |
| HU164250B (enrdf_load_stackoverflow) | 1974-01-28 |
| IE36187B1 (en) | 1976-09-01 |
| CA988529A (en) | 1976-05-04 |
| IE36186L (en) | 1972-09-26 |
| CH574433A5 (enrdf_load_stackoverflow) | 1976-04-15 |
| IE36186B1 (en) | 1976-09-01 |
| DE2214501A1 (de) | 1972-10-05 |
| NL7203979A (enrdf_load_stackoverflow) | 1972-09-28 |
| SE7416328L (enrdf_load_stackoverflow) | 1974-12-27 |
| FR2130655B1 (enrdf_load_stackoverflow) | 1975-06-20 |
| AU463471B2 (en) | 1975-07-08 |
| IL39036A0 (en) | 1972-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |