GB1364088A - 3-substituted-thio-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof - Google Patents
3-substituted-thio-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereofInfo
- Publication number
- GB1364088A GB1364088A GB6058871A GB6058871A GB1364088A GB 1364088 A GB1364088 A GB 1364088A GB 6058871 A GB6058871 A GB 6058871A GB 6058871 A GB6058871 A GB 6058871A GB 1364088 A GB1364088 A GB 1364088A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cephem
- thio
- substituted
- methyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZNVOUDVNEIRTGV-BBZZFXJRSA-N (6r)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-4-carboxylic acid Chemical class S1C(C(O)=O)C=CN2C(=O)C(N)[C@H]21 ZNVOUDVNEIRTGV-BBZZFXJRSA-N 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 2
- 229940124587 cephalosporin Drugs 0.000 abstract 2
- 150000001780 cephalosporins Chemical class 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- -1 heterocyclic radical Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12946770A JPS505719B1 (enrdf_load_stackoverflow) | 1970-12-30 | 1970-12-30 | |
| JP4408871A JPS5439392B1 (enrdf_load_stackoverflow) | 1971-06-19 | 1971-06-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1364088A true GB1364088A (en) | 1974-08-21 |
Family
ID=26383937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6058871A Expired GB1364088A (en) | 1970-12-30 | 1971-12-29 | 3-substituted-thio-methyl-3-cephem-4-carboxylic acid derivatives and preparation thereof |
Country Status (6)
| Country | Link |
|---|---|
| CH (1) | CH611301A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2164561A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2120121B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1364088A (enrdf_load_stackoverflow) |
| NL (1) | NL7117960A (enrdf_load_stackoverflow) |
| SE (1) | SE415180B (enrdf_load_stackoverflow) |
-
1971
- 1971-12-23 CH CH1887271A patent/CH611301A5/xx not_active IP Right Cessation
- 1971-12-24 DE DE19712164561 patent/DE2164561A1/de not_active Ceased
- 1971-12-28 NL NL7117960A patent/NL7117960A/xx not_active Application Discontinuation
- 1971-12-28 SE SE1676371A patent/SE415180B/xx unknown
- 1971-12-29 FR FR7147357A patent/FR2120121B1/fr not_active Expired
- 1971-12-29 GB GB6058871A patent/GB1364088A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7117960A (enrdf_load_stackoverflow) | 1972-07-04 |
| CH611301A5 (en) | 1979-05-31 |
| FR2120121B1 (enrdf_load_stackoverflow) | 1975-08-01 |
| SE415180B (sv) | 1980-09-15 |
| DE2164561A1 (de) | 1972-07-27 |
| FR2120121A1 (enrdf_load_stackoverflow) | 1972-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |