GB1360312A - N-substituted derivatives of bleomycins - Google Patents

N-substituted derivatives of bleomycins

Info

Publication number
GB1360312A
GB1360312A GB1958572A GB1958572A GB1360312A GB 1360312 A GB1360312 A GB 1360312A GB 1958572 A GB1958572 A GB 1958572A GB 1958572 A GB1958572 A GB 1958572A GB 1360312 A GB1360312 A GB 1360312A
Authority
GB
United Kingdom
Prior art keywords
bleomycins
hydrogen
amino
alkyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1958572A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP46027553A external-priority patent/JPS5010841B1/ja
Priority claimed from JP7543071A external-priority patent/JPS5031122B2/ja
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Publication of GB1360312A publication Critical patent/GB1360312A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
GB1958572A 1971-04-28 1972-04-27 N-substituted derivatives of bleomycins Expired GB1360312A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP46027553A JPS5010841B1 (enrdf_load_stackoverflow) 1971-04-28 1971-04-28
JP7543071A JPS5031122B2 (enrdf_load_stackoverflow) 1971-09-29 1971-09-29

Publications (1)

Publication Number Publication Date
GB1360312A true GB1360312A (en) 1974-07-17

Family

ID=26365487

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1958572A Expired GB1360312A (en) 1971-04-28 1972-04-27 N-substituted derivatives of bleomycins

Country Status (7)

Country Link
CA (1) CA982122A (enrdf_load_stackoverflow)
CH (2) CH575912A5 (enrdf_load_stackoverflow)
CS (1) CS167982B2 (enrdf_load_stackoverflow)
DE (1) DE2220766C3 (enrdf_load_stackoverflow)
FR (1) FR2134653B1 (enrdf_load_stackoverflow)
GB (1) GB1360312A (enrdf_load_stackoverflow)
NL (1) NL150802B (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057618A (en) * 1976-04-30 1977-11-08 University Patents, Inc. Radioiodinated bleomycin
JPS58116497A (ja) * 1981-12-29 1983-07-11 Microbial Chem Res Found アミノプロピルアミノブレオマイシン誘導体及びその製造法

Also Published As

Publication number Publication date
DE2220766C3 (de) 1978-08-24
FR2134653A1 (enrdf_load_stackoverflow) 1972-12-08
DE2220766A1 (de) 1972-11-16
CH577465A5 (enrdf_load_stackoverflow) 1976-07-15
NL150802B (nl) 1976-09-15
CA982122A (en) 1976-01-20
CS167982B2 (en) 1976-05-28
NL7205753A (enrdf_load_stackoverflow) 1972-10-31
CH575912A5 (enrdf_load_stackoverflow) 1976-05-31
AU4153072A (en) 1973-06-14
DE2220766B2 (de) 1978-01-12
FR2134653B1 (enrdf_load_stackoverflow) 1975-12-26

Similar Documents

Publication Publication Date Title
ES8206443A1 (es) Un procedimiento para preparar un derivado de amidina
GB1360312A (en) N-substituted derivatives of bleomycins
GB1446980A (en) A-aminooxy-carboxylic acid hydrazides
GB966222A (en) Derivatives of cephalosporin c
ES400820A1 (es) Procedimiento para preparar 3-amino-imidazo (1,5-a) piridi-nas.
FR2383175A1 (fr) Procede de preparation de derives de phenylpyridazinone
ES404744A1 (es) Un procedimiento para producir derivados de cefalosporina.
GB1398655A (en) Process for the production of lactam hydrazones of aromatic systems
SE7504794L (sv) Forfarande for framstellning av cyanursyra
KR830009077A (ko) 푸란 유도체의 제조방법
GB934935A (en) Guanidine compounds
GB1076937A (en) ª‰-arylsulphonylethyl thiosulphuric acids, their metal salts and process for preparing them
ES419319A1 (es) Un procedimiento para la obtencion de derivados de acidos 3-benzoilfenilalcanoicos.
ES328674A1 (es) Procedimiento para la produccion de alcaloides.
KR870002110A (ko) 구아니디노티아졸 유도체의 제조방법
GB937617A (en) Improvements in or relating to the modification of thermoplastic maleimide polymers
US3056798A (en) Process for the preparation of 2-(2'-furfurylmercapto)pyridine-1-oxides
ES411401A1 (es) Un procedimiento para la obtencion de derivados de p-aceta-mol.
GB977479A (en) New and useful organopolysiloxanes and use thereof
KR900017996A (ko) 비스이미드의 합성방법
GB1323020A (en) Process for the preparation of 1-substituted 4-amino-3-pyrrolin- 2-ones
ES461157A1 (es) Procedimiento para la obtencion de compuestos de 2-oxa-7,9- diaza-biciclo (4,2,2) decano.
ES404197A1 (es) Un procedimiento para la produccion de un compuesto deriva-do de 2-cefema o de 3-cefema.
IE39128B1 (en) A process for the production of oxazolines
ES434377A1 (es) Procedimiento para la preparacion de compuestos heteroci- clicos derivados de acidos benzimidazolcarbamicos.

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee