CS167982B2 - Method of bleomycines' n-substituted derivatives production - Google Patents

Method of bleomycines' n-substituted derivatives production

Info

Publication number
CS167982B2
CS167982B2 CS291072A CS291072A CS167982B2 CS 167982 B2 CS167982 B2 CS 167982B2 CS 291072 A CS291072 A CS 291072A CS 291072 A CS291072 A CS 291072A CS 167982 B2 CS167982 B2 CS 167982B2
Authority
CS
Czechoslovakia
Prior art keywords
bleomycines
substituted derivatives
derivatives production
production
substituted
Prior art date
Application number
CS291072A
Other languages
Czech (cs)
Inventor
Hamao Umezawa
Yuya Nakayama
Mamoru Kunishima
Midori Matsubara
Original Assignee
Hamao Umezawa
Yuya Nakayama
Mamoru Kunishima
Midori Matsubara
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2755371A external-priority patent/JPS5010841B1/ja
Priority claimed from JP7543071A external-priority patent/JPS5031122B2/ja
Application filed by Hamao Umezawa, Yuya Nakayama, Mamoru Kunishima, Midori Matsubara filed Critical Hamao Umezawa
Publication of CS167982B2 publication Critical patent/CS167982B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CS291072A 1971-04-28 1972-04-28 Method of bleomycines' n-substituted derivatives production CS167982B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2755371A JPS5010841B1 (en) 1971-04-28 1971-04-28
JP7543071A JPS5031122B2 (en) 1971-09-29 1971-09-29

Publications (1)

Publication Number Publication Date
CS167982B2 true CS167982B2 (en) 1976-05-28

Family

ID=26365487

Family Applications (1)

Application Number Title Priority Date Filing Date
CS291072A CS167982B2 (en) 1971-04-28 1972-04-28 Method of bleomycines' n-substituted derivatives production

Country Status (7)

Country Link
CA (1) CA982122A (en)
CH (2) CH577465A5 (en)
CS (1) CS167982B2 (en)
DE (1) DE2220766C3 (en)
FR (1) FR2134653B1 (en)
GB (1) GB1360312A (en)
NL (1) NL150802B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057618A (en) * 1976-04-30 1977-11-08 University Patents, Inc. Radioiodinated bleomycin
JPS58116497A (en) * 1981-12-29 1983-07-11 Microbial Chem Res Found Aminopropylaminobleomycin derivative and its preparation

Also Published As

Publication number Publication date
DE2220766C3 (en) 1978-08-24
GB1360312A (en) 1974-07-17
CH575912A5 (en) 1976-05-31
AU4153072A (en) 1973-06-14
CH577465A5 (en) 1976-07-15
NL7205753A (en) 1972-10-31
DE2220766B2 (en) 1978-01-12
FR2134653B1 (en) 1975-12-26
NL150802B (en) 1976-09-15
CA982122A (en) 1976-01-20
DE2220766A1 (en) 1972-11-16
FR2134653A1 (en) 1972-12-08

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