CA982122A - N-substituted derivatives of bleomycins - Google Patents

N-substituted derivatives of bleomycins

Info

Publication number
CA982122A
CA982122A CA140,754A CA140754A CA982122A CA 982122 A CA982122 A CA 982122A CA 140754 A CA140754 A CA 140754A CA 982122 A CA982122 A CA 982122A
Authority
CA
Canada
Prior art keywords
bleomycins
substituted derivatives
derivatives
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA140,754A
Other versions
CA140754S (en
Inventor
Hamao Umezawa
Mamoru Kunishima
Yuya Nakayama
Midori Matsubara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2755371A external-priority patent/JPS5010841B1/ja
Priority claimed from JP7543071A external-priority patent/JPS5031122B2/ja
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Application granted granted Critical
Publication of CA982122A publication Critical patent/CA982122A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40—Thiophene-2-carboxylic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G11/00—Antibiotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA140,754A 1971-04-28 1972-04-27 N-substituted derivatives of bleomycins Expired CA982122A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2755371A JPS5010841B1 (en) 1971-04-28 1971-04-28
JP7543071A JPS5031122B2 (en) 1971-09-29 1971-09-29

Publications (1)

Publication Number Publication Date
CA982122A true CA982122A (en) 1976-01-20

Family

ID=26365487

Family Applications (1)

Application Number Title Priority Date Filing Date
CA140,754A Expired CA982122A (en) 1971-04-28 1972-04-27 N-substituted derivatives of bleomycins

Country Status (7)

Country Link
CA (1) CA982122A (en)
CH (2) CH577465A5 (en)
CS (1) CS167982B2 (en)
DE (1) DE2220766C3 (en)
FR (1) FR2134653B1 (en)
GB (1) GB1360312A (en)
NL (1) NL150802B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057618A (en) * 1976-04-30 1977-11-08 University Patents, Inc. Radioiodinated bleomycin
JPS58116497A (en) * 1981-12-29 1983-07-11 Microbial Chem Res Found Aminopropylaminobleomycin derivative and its preparation

Also Published As

Publication number Publication date
CS167982B2 (en) 1976-05-28
DE2220766C3 (en) 1978-08-24
GB1360312A (en) 1974-07-17
CH575912A5 (en) 1976-05-31
AU4153072A (en) 1973-06-14
CH577465A5 (en) 1976-07-15
NL7205753A (en) 1972-10-31
DE2220766B2 (en) 1978-01-12
FR2134653B1 (en) 1975-12-26
NL150802B (en) 1976-09-15
DE2220766A1 (en) 1972-11-16
FR2134653A1 (en) 1972-12-08

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