NL150802B - PROCEDURE FOR PREPARING N-SUBSTITUTED BLEOMYCINE DERIVATIVES. - Google Patents
PROCEDURE FOR PREPARING N-SUBSTITUTED BLEOMYCINE DERIVATIVES.Info
- Publication number
- NL150802B NL150802B NL7205753A NL7205753A NL150802B NL 150802 B NL150802 B NL 150802B NL 7205753 A NL7205753 A NL 7205753A NL 7205753 A NL7205753 A NL 7205753A NL 150802 B NL150802 B NL 150802B
- Authority
- NL
- Netherlands
- Prior art keywords
- bleomycine
- derivatives
- substituted
- preparing
- procedure
- Prior art date
Links
- OYVAGSVQBOHSSS-WXFSZRTFSA-O bleomycin Chemical class N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](OC1C(C(O)C(O)C(CO)O1)OC1C(C(OC(N)=O)C(O)C(CO)O1)O)C=1NC=NC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-WXFSZRTFSA-O 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G11/00—Antibiotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP46027553A JPS5010841B1 (en) | 1971-04-28 | 1971-04-28 | |
| JP7543071A JPS5031122B2 (en) | 1971-09-29 | 1971-09-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL7205753A NL7205753A (en) | 1972-10-31 |
| NL150802B true NL150802B (en) | 1976-09-15 |
Family
ID=26365487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7205753A NL150802B (en) | 1971-04-28 | 1972-04-27 | PROCEDURE FOR PREPARING N-SUBSTITUTED BLEOMYCINE DERIVATIVES. |
Country Status (7)
| Country | Link |
|---|---|
| CA (1) | CA982122A (en) |
| CH (2) | CH577465A5 (en) |
| CS (1) | CS167982B2 (en) |
| DE (1) | DE2220766C3 (en) |
| FR (1) | FR2134653B1 (en) |
| GB (1) | GB1360312A (en) |
| NL (1) | NL150802B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057618A (en) * | 1976-04-30 | 1977-11-08 | University Patents, Inc. | Radioiodinated bleomycin |
| JPS58116497A (en) * | 1981-12-29 | 1983-07-11 | Microbial Chem Res Found | Aminopropylaminobleomycin derivative and its preparation |
-
1972
- 1972-04-27 CH CH246975A patent/CH577465A5/xx not_active IP Right Cessation
- 1972-04-27 DE DE19722220766 patent/DE2220766C3/en not_active Expired
- 1972-04-27 GB GB1958572A patent/GB1360312A/en not_active Expired
- 1972-04-27 CH CH626372A patent/CH575912A5/xx not_active IP Right Cessation
- 1972-04-27 CA CA140,754A patent/CA982122A/en not_active Expired
- 1972-04-27 NL NL7205753A patent/NL150802B/en not_active IP Right Cessation
- 1972-04-28 CS CS291072A patent/CS167982B2/en unknown
- 1972-04-28 FR FR7215254A patent/FR2134653B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2220766B2 (en) | 1978-01-12 |
| CH575912A5 (en) | 1976-05-31 |
| CH577465A5 (en) | 1976-07-15 |
| NL7205753A (en) | 1972-10-31 |
| FR2134653B1 (en) | 1975-12-26 |
| DE2220766C3 (en) | 1978-08-24 |
| CS167982B2 (en) | 1976-05-28 |
| CA982122A (en) | 1976-01-20 |
| DE2220766A1 (en) | 1972-11-16 |
| GB1360312A (en) | 1974-07-17 |
| FR2134653A1 (en) | 1972-12-08 |
| AU4153072A (en) | 1973-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| V1 | Lapsed because of non-payment of the annual fee | ||
| NL80 | Abbreviated name of patent owner mentioned of already nullified patent |
Owner name: NIPPON |