GB1356216A - Cyclic acetals of the 10-piperazinodibenzo b,f thiepin series and methods of preparing the same - Google Patents
Cyclic acetals of the 10-piperazinodibenzo b,f thiepin series and methods of preparing the sameInfo
- Publication number
- GB1356216A GB1356216A GB2718572A GB2718572A GB1356216A GB 1356216 A GB1356216 A GB 1356216A GB 2718572 A GB2718572 A GB 2718572A GB 2718572 A GB2718572 A GB 2718572A GB 1356216 A GB1356216 A GB 1356216A
- Authority
- GB
- United Kingdom
- Prior art keywords
- thiepin
- dioxolan
- methylthio
- ethyl
- dibenzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Cyclic acetals Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- VRACAYYCPANFGY-UHFFFAOYSA-N 1-[2-(1,3-dioxolan-2-yl)ethyl]-4-(3-methylsulfanylbenzo[b][1]benzothiepin-5-yl)piperazine Chemical compound CSC=1C=CC2=C(C(=CC3=C(S2)C=CC=C3)N3CCN(CC3)CCC3OCCO3)C1 VRACAYYCPANFGY-UHFFFAOYSA-N 0.000 abstract 1
- ZRYJPBASNVAHTC-UHFFFAOYSA-N 1-[2-(1,3-dioxolan-2-yl)ethyl]piperazine Chemical compound O1CCOC1CCN1CCNCC1 ZRYJPBASNVAHTC-UHFFFAOYSA-N 0.000 abstract 1
- GBKZPLIJKMRYTE-UHFFFAOYSA-N 2-(2-chloroethyl)-1,3-dioxolane Chemical compound ClCCC1OCCO1 GBKZPLIJKMRYTE-UHFFFAOYSA-N 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- UZVGSSNIUNSOFA-UHFFFAOYSA-N dibenzofuran-1-carboxylic acid Chemical class O1C2=CC=CC=C2C2=C1C=CC=C2C(=O)O UZVGSSNIUNSOFA-UHFFFAOYSA-N 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- BXHBVHRKLLYVQK-UHFFFAOYSA-N ethyl 4-[2-(1,3-dioxolan-2-yl)ethyl]piperazine-1-carboxylate Chemical compound O1C(OCC1)CCN1CCN(CC1)C(=O)OCC BXHBVHRKLLYVQK-UHFFFAOYSA-N 0.000 abstract 1
- LNOQURRKNJKKBU-UHFFFAOYSA-N ethyl piperazine-1-carboxylate Chemical compound CCOC(=O)N1CCNCC1 LNOQURRKNJKKBU-UHFFFAOYSA-N 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- XJDNKRIXUMDJCW-UHFFFAOYSA-J titanium tetrachloride Chemical compound Cl[Ti](Cl)(Cl)Cl XJDNKRIXUMDJCW-UHFFFAOYSA-J 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS431071A CS153835B1 (enExample) | 1971-06-11 | 1971-06-11 | |
| CS68572A CS156878B1 (enExample) | 1972-02-03 | 1972-02-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1356216A true GB1356216A (en) | 1974-06-12 |
Family
ID=25745324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2718572A Expired GB1356216A (en) | 1971-06-11 | 1972-06-09 | Cyclic acetals of the 10-piperazinodibenzo b,f thiepin series and methods of preparing the same |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5231354B1 (enExample) |
| CA (1) | CA992083A (enExample) |
| CH (1) | CH575945A5 (enExample) |
| FR (1) | FR2140684B1 (enExample) |
| GB (1) | GB1356216A (enExample) |
| NL (1) | NL7207834A (enExample) |
| SE (1) | SE376239B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57152707A (en) * | 1981-03-17 | 1982-09-21 | Citizen Watch Co Ltd | Oscillator having series capacity |
-
1972
- 1972-06-01 CH CH813772A patent/CH575945A5/xx not_active IP Right Cessation
- 1972-06-09 GB GB2718572A patent/GB1356216A/en not_active Expired
- 1972-06-09 SE SE7207648A patent/SE376239B/xx unknown
- 1972-06-09 NL NL7207834A patent/NL7207834A/xx unknown
- 1972-06-10 JP JP47058114A patent/JPS5231354B1/ja active Pending
- 1972-06-12 FR FR7221112A patent/FR2140684B1/fr not_active Expired
- 1972-06-12 CA CA144,485A patent/CA992083A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA992083A (en) | 1976-06-29 |
| FR2140684B1 (enExample) | 1976-03-05 |
| FR2140684A1 (enExample) | 1973-01-19 |
| CH575945A5 (enExample) | 1976-05-31 |
| DE2228283B2 (de) | 1975-11-06 |
| SE376239B (enExample) | 1975-05-12 |
| JPS5231354B1 (enExample) | 1977-08-13 |
| DE2228283A1 (de) | 1973-01-04 |
| NL7207834A (enExample) | 1972-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |