GB1354246A - 1,4-dihydro-3-2h-isoquinoline derivatives and a process for the preparation thereof - Google Patents
1,4-dihydro-3-2h-isoquinoline derivatives and a process for the preparation thereofInfo
- Publication number
- GB1354246A GB1354246A GB2389672A GB2389672A GB1354246A GB 1354246 A GB1354246 A GB 1354246A GB 2389672 A GB2389672 A GB 2389672A GB 2389672 A GB2389672 A GB 2389672A GB 1354246 A GB1354246 A GB 1354246A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- prepared
- reacting
- group
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002825 nitriles Chemical class 0.000 abstract 3
- -1 trifluoromethylphenyl Chemical group 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 229920000137 polyphosphoric acid Polymers 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- MGZGPQCRWVOGFE-UHFFFAOYSA-N 2,4-dihydro-1h-isoquinolin-3-one Chemical class C1=CC=C2CNC(=O)CC2=C1 MGZGPQCRWVOGFE-UHFFFAOYSA-N 0.000 abstract 1
- LSBDFXRDZJMBSC-UHFFFAOYSA-N 2-phenylacetamide Chemical class NC(=O)CC1=CC=CC=C1 LSBDFXRDZJMBSC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
- 150000007962 benzene acetonitriles Chemical class 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000006501 nitrophenyl group Chemical group 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUMA002239 | 1971-05-27 | ||
| HUMA002238 | 1971-05-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1354246A true GB1354246A (en) | 1974-06-05 |
Family
ID=26318504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2389672A Expired GB1354246A (en) | 1971-05-27 | 1972-05-22 | 1,4-dihydro-3-2h-isoquinoline derivatives and a process for the preparation thereof |
Country Status (6)
| Country | Link |
|---|---|
| AT (1) | AT319248B (enExample) |
| BE (1) | BE784037A (enExample) |
| DE (1) | DE2225669A1 (enExample) |
| FR (1) | FR2139063B1 (enExample) |
| GB (1) | GB1354246A (enExample) |
| NL (1) | NL7207177A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU167263B (enExample) * | 1973-02-12 | 1975-09-27 | ||
| DE2309367A1 (de) * | 1973-02-24 | 1974-09-05 | Hoechst Ag | 1,4-dihydro-4-h-isochinolinderivate und verfahren zu ihrer herstellung |
| IL45823A (en) * | 1973-10-20 | 1977-10-31 | Hoechst Ag | Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives |
-
1972
- 1972-05-22 GB GB2389672A patent/GB1354246A/en not_active Expired
- 1972-05-24 AT AT447572A patent/AT319248B/de not_active IP Right Cessation
- 1972-05-25 FR FR7218742A patent/FR2139063B1/fr not_active Expired
- 1972-05-26 DE DE19722225669 patent/DE2225669A1/de active Pending
- 1972-05-26 BE BE784037A patent/BE784037A/xx not_active IP Right Cessation
- 1972-05-26 NL NL7207177A patent/NL7207177A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2225669A1 (de) | 1972-12-28 |
| BE784037A (fr) | 1972-09-18 |
| AT319248B (de) | 1974-12-10 |
| FR2139063B1 (enExample) | 1975-12-26 |
| FR2139063A1 (enExample) | 1973-01-05 |
| NL7207177A (enExample) | 1972-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |