GB1352380A - Quinone derivatives - Google Patents
Quinone derivativesInfo
- Publication number
- GB1352380A GB1352380A GB2417671A GB2417671A GB1352380A GB 1352380 A GB1352380 A GB 1352380A GB 2417671 A GB2417671 A GB 2417671A GB 2417671 A GB2417671 A GB 2417671A GB 1352380 A GB1352380 A GB 1352380A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydrogen atom
- general formula
- methyl
- resulting
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004059 quinone derivatives Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 11
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- XFWDWSKJNMQVAZ-UHFFFAOYSA-N 4-(2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanoic acid Chemical class CC=1C(C=CC(C1CCCC(=O)O)=O)=O XFWDWSKJNMQVAZ-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- VTWDKFNVVLAELH-UHFFFAOYSA-N 2-methylcyclohexa-2,5-diene-1,4-dione Chemical compound CC1=CC(=O)C=CC1=O VTWDKFNVVLAELH-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 230000003647 oxidation Effects 0.000 abstract 2
- 238000007254 oxidation reaction Methods 0.000 abstract 2
- 150000002978 peroxides Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 abstract 1
- GNCJLWPTDPAOPH-UHFFFAOYSA-N 4-(2-hydroxy-6-methylphenyl)-4-oxobutanoic acid Chemical compound OC1=C(C(=O)CCC(=O)O)C(=CC=C1)C GNCJLWPTDPAOPH-UHFFFAOYSA-N 0.000 abstract 1
- JTIQRBSKVBYEJL-UHFFFAOYSA-N 4-(2-hydroxy-6-methylphenyl)butanoic acid Chemical compound OC1=C(C(=CC=C1)C)CCCC(=O)O JTIQRBSKVBYEJL-UHFFFAOYSA-N 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- 229930003448 Vitamin K Natural products 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000004973 alkali metal peroxides Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 abstract 1
- RINCXYDBBGOEEQ-UHFFFAOYSA-N succinic anhydride Chemical compound O=C1CCC(=O)O1 RINCXYDBBGOEEQ-UHFFFAOYSA-N 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 235000019168 vitamin K Nutrition 0.000 abstract 1
- 239000011712 vitamin K Substances 0.000 abstract 1
- 150000003721 vitamin K derivatives Chemical class 0.000 abstract 1
- 229940046010 vitamin k Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C66/00—Quinone carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2249770A JPS4843106B1 (enExample) | 1970-03-17 | 1970-03-17 | |
| JP2280570A JPS4843342B1 (enExample) | 1970-03-18 | 1970-03-18 | |
| JP6693870A JPS5010574B1 (enExample) | 1970-07-30 | 1970-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1352380A true GB1352380A (en) | 1974-05-08 |
Family
ID=27283868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2417671A Expired GB1352380A (en) | 1970-03-17 | 1971-04-19 | Quinone derivatives |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE764384A (enExample) |
| DE (1) | DE2112147A1 (enExample) |
| FR (1) | FR2085716B1 (enExample) |
| GB (1) | GB1352380A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957836A (en) * | 1973-07-02 | 1976-05-18 | Takeda Chemical Industries, Ltd. | Quinone derivatives |
| JPS5919930B2 (ja) * | 1974-05-02 | 1984-05-09 | 武田薬品工業株式会社 | キノン酸誘導体の製造法 |
| MX9203040A (es) * | 1984-08-01 | 1992-07-31 | Takeda Chemical Industries Ltd | Derivados de quinona y composicion farmaceutica que los contiene. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2398418A (en) * | 1943-08-27 | 1946-04-16 | Louis F Fieser | Introduction of organic radicals into quinones |
-
1971
- 1971-03-13 DE DE19712112147 patent/DE2112147A1/de active Pending
- 1971-03-16 FR FR7109165A patent/FR2085716B1/fr not_active Expired
- 1971-03-17 BE BE764384A patent/BE764384A/xx not_active IP Right Cessation
- 1971-04-19 GB GB2417671A patent/GB1352380A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2085716A1 (enExample) | 1971-12-31 |
| FR2085716B1 (enExample) | 1975-06-06 |
| DE2112147A1 (de) | 1971-09-30 |
| BE764384A (fr) | 1971-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |