GB1351533A - Oxoprostenoic acid derivatives - Google Patents
Oxoprostenoic acid derivativesInfo
- Publication number
- GB1351533A GB1351533A GB4381071A GB4381071A GB1351533A GB 1351533 A GB1351533 A GB 1351533A GB 4381071 A GB4381071 A GB 4381071A GB 4381071 A GB4381071 A GB 4381071A GB 1351533 A GB1351533 A GB 1351533A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formyl
- methyl
- cyclopentenyl
- methoxycarbonylhexyl
- heptanoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 5
- NNOJWZIBHANBJD-OALUTQOASA-N 7-[(1S,2S)-2-octylcyclopentyl]hept-2-enoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCC=CC(O)=O NNOJWZIBHANBJD-OALUTQOASA-N 0.000 abstract 3
- MNWFXJYAOYHMED-UHFFFAOYSA-N heptanoic acid Chemical compound CCCCCCC(O)=O MNWFXJYAOYHMED-UHFFFAOYSA-N 0.000 abstract 3
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 2-tetrahydropyranyl Chemical group 0.000 abstract 1
- AWQSAIIDOMEEOD-UHFFFAOYSA-N 5,5-Dimethyl-4-(3-oxobutyl)dihydro-2(3H)-furanone Chemical compound CC(=O)CCC1CC(=O)OC1(C)C AWQSAIIDOMEEOD-UHFFFAOYSA-N 0.000 abstract 1
- XLFGFYRDTOAYFX-UHFFFAOYSA-N 7-(2-formyl-3-hydroxycyclopentyl)heptanoic acid Chemical compound C(=O)C1C(CCC1O)CCCCCCC(=O)O XLFGFYRDTOAYFX-UHFFFAOYSA-N 0.000 abstract 1
- SPXILGOITDKINO-UHFFFAOYSA-N 7-(2-formylcyclopenten-1-yl)heptanoic acid Chemical compound OC(=O)CCCCCCC1=C(CCC1)C=O SPXILGOITDKINO-UHFFFAOYSA-N 0.000 abstract 1
- AELXVJYDPSIRRT-UHFFFAOYSA-N 7-(2-formylcyclopentyl)heptanoic acid Chemical compound OC(=O)CCCCCCC1CCCC1C=O AELXVJYDPSIRRT-UHFFFAOYSA-N 0.000 abstract 1
- ABRHGWGRAMEKSM-UHFFFAOYSA-N 7-[2-[carboxy(hydroxy)methyl]cyclopenten-1-yl]heptanoic acid Chemical compound C(=O)(O)CCCCCCC1=C(CCC1)C(C(=O)O)O ABRHGWGRAMEKSM-UHFFFAOYSA-N 0.000 abstract 1
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- VELDYOPRLMJFIK-UHFFFAOYSA-N cyclopentanecarbaldehyde Chemical compound O=CC1CCCC1 VELDYOPRLMJFIK-UHFFFAOYSA-N 0.000 abstract 1
- JBDSSBMEKXHSJF-UHFFFAOYSA-M cyclopentanecarboxylate Chemical compound [O-]C(=O)C1CCCC1 JBDSSBMEKXHSJF-UHFFFAOYSA-M 0.000 abstract 1
- RALDHUZFXJKFQB-UHFFFAOYSA-N cyclopentene-1-carbaldehyde Chemical class O=CC1=CCCC1 RALDHUZFXJKFQB-UHFFFAOYSA-N 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- RGDKNPBBAUQCKR-UHFFFAOYSA-N ethyl 4-(7-methoxy-7-oxoheptyl)-1-oxaspiro[2.4]heptane-2-carboxylate Chemical compound C(C)OC(=O)C1OC12C(CCC2)CCCCCCC(=O)OC RGDKNPBBAUQCKR-UHFFFAOYSA-N 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- QBZHWIQWKXQIGY-UHFFFAOYSA-N methyl 7-(2-formyl-3-hydroxycyclopentyl)heptanoate Chemical compound C(=O)C1C(CCC1O)CCCCCCC(=O)OC QBZHWIQWKXQIGY-UHFFFAOYSA-N 0.000 abstract 1
- UDWFHJFHUPLROQ-UHFFFAOYSA-N methyl 7-(2-formylcyclopenten-1-yl)heptanoate Chemical compound COC(=O)CCCCCCC1=C(C=O)CCC1 UDWFHJFHUPLROQ-UHFFFAOYSA-N 0.000 abstract 1
- QULMNLGXMKSYRK-UHFFFAOYSA-N methyl 7-[2-(2-ethoxy-1-hydroxy-2-oxoethyl)cyclopent-2-en-1-yl]heptanoate Chemical compound COC(=O)CCCCCCC1CCC=C1C(C(=O)OCC)O QULMNLGXMKSYRK-UHFFFAOYSA-N 0.000 abstract 1
- UICBLBMEGWINJG-UHFFFAOYSA-N methyl 7-[2-(2-ethoxy-1-hydroxy-2-oxoethyl)cyclopenten-1-yl]heptanoate Chemical compound COC(=O)CCCCCCC1=C(CCC1)C(C(=O)OCC)O UICBLBMEGWINJG-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- VBQCHPIMZGQLAZ-UHFFFAOYSA-N phosphorane Chemical class [PH5] VBQCHPIMZGQLAZ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45082238A JPS514990B1 (xx) | 1970-09-19 | 1970-09-19 | |
| JP8480070A JPS4928749B1 (xx) | 1970-09-28 | 1970-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1351533A true GB1351533A (en) | 1974-05-01 |
Family
ID=26423252
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4380771A Expired GB1351532A (en) | 1970-09-19 | 1971-09-20 | Prostenoic acid derivatives |
| GB4381071A Expired GB1351533A (en) | 1970-09-19 | 1971-09-20 | Oxoprostenoic acid derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4380771A Expired GB1351532A (en) | 1970-09-19 | 1971-09-20 | Prostenoic acid derivatives |
Country Status (7)
| Country | Link |
|---|---|
| BE (2) | BE772837A (xx) |
| CA (2) | CA951723A (xx) |
| DE (2) | DE2147315A1 (xx) |
| FR (2) | FR2106630B1 (xx) |
| GB (2) | GB1351532A (xx) |
| NL (2) | NL7112746A (xx) |
| SE (2) | SE375090B (xx) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887587A (en) * | 1972-04-17 | 1975-06-03 | Pfizer | Synthesis of prostaglandins of the one-series |
-
1971
- 1971-09-15 CA CA122,916,A patent/CA951723A/en not_active Expired
- 1971-09-16 CA CA123,024A patent/CA974987A/en not_active Expired
- 1971-09-16 NL NL7112746A patent/NL7112746A/xx unknown
- 1971-09-17 NL NL7112804A patent/NL7112804A/xx unknown
- 1971-09-17 SE SE1183771A patent/SE375090B/xx unknown
- 1971-09-17 SE SE1183671A patent/SE375089B/xx unknown
- 1971-09-18 DE DE19712147315 patent/DE2147315A1/de active Pending
- 1971-09-18 DE DE19712147316 patent/DE2147316A1/de active Pending
- 1971-09-20 FR FR7133683A patent/FR2106630B1/fr not_active Expired
- 1971-09-20 BE BE772837A patent/BE772837A/xx unknown
- 1971-09-20 BE BE772836A patent/BE772836A/nl unknown
- 1971-09-20 GB GB4380771A patent/GB1351532A/en not_active Expired
- 1971-09-20 GB GB4381071A patent/GB1351533A/en not_active Expired
- 1971-09-20 FR FR7133684A patent/FR2106631B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA951723A (en) | 1974-07-23 |
| FR2106630A1 (xx) | 1972-05-05 |
| SE375090B (xx) | 1975-04-07 |
| NL7112804A (xx) | 1972-03-21 |
| FR2106631A1 (xx) | 1972-05-05 |
| DE2147315A1 (de) | 1972-03-23 |
| NL7112746A (xx) | 1972-03-21 |
| BE772836A (nl) | 1972-01-17 |
| FR2106631B1 (xx) | 1975-08-01 |
| SE375089B (xx) | 1975-04-07 |
| BE772837A (fr) | 1972-01-17 |
| GB1351532A (en) | 1974-05-01 |
| CA974987A (en) | 1975-09-23 |
| DE2147316A1 (de) | 1972-05-25 |
| FR2106630B1 (xx) | 1975-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |