GB1351532A - Prostenoic acid derivatives - Google Patents
Prostenoic acid derivativesInfo
- Publication number
- GB1351532A GB1351532A GB4380771A GB4380771A GB1351532A GB 1351532 A GB1351532 A GB 1351532A GB 4380771 A GB4380771 A GB 4380771A GB 4380771 A GB4380771 A GB 4380771A GB 1351532 A GB1351532 A GB 1351532A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sept
- acid derivatives
- alkyl
- prostaglandins
- prostenoic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NNOJWZIBHANBJD-OALUTQOASA-N 7-[(1S,2S)-2-octylcyclopentyl]hept-2-enoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCC=CC(O)=O NNOJWZIBHANBJD-OALUTQOASA-N 0.000 title 1
- -1 2-tetrahydropyranyl Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001595 contractor effect Effects 0.000 abstract 1
- 125000004979 cyclopentylene group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 210000003405 ileum Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1351532 Compositions comprising prostaglandins SANKYO CO Ltd 20 Sept 1971 [19 Sept 1970 28 Sept 1970] 43807/71 Heading A5B [Also in Division C2] Pharmaceutical compositions, suitable for parenteral administration, contain novel prostaglandins of the formula: wherein A is C 1-10 alkylene, R<SP>1</SP> is C 1-10 alkyl, R<SP>2</SP> is H or C 1-5 alkyl and the cyclopentylene is a group of the formulae: wherein R<SP>3</SP> is H or 2-tetrahydropyranyl; or alklali or alkaline earth metal salts thereof when R<SP>2</SP> is H and pharmaceutical carriers or diluents, and if desired, known prostaglandens. The compounds possess uterine and ileum contracting activities.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP45082238A JPS514990B1 (en) | 1970-09-19 | 1970-09-19 | |
| JP8480070A JPS4928749B1 (en) | 1970-09-28 | 1970-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1351532A true GB1351532A (en) | 1974-05-01 |
Family
ID=26423252
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4380771A Expired GB1351532A (en) | 1970-09-19 | 1971-09-20 | Prostenoic acid derivatives |
| GB4381071A Expired GB1351533A (en) | 1970-09-19 | 1971-09-20 | Oxoprostenoic acid derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4381071A Expired GB1351533A (en) | 1970-09-19 | 1971-09-20 | Oxoprostenoic acid derivatives |
Country Status (7)
| Country | Link |
|---|---|
| BE (2) | BE772837A (en) |
| CA (2) | CA951723A (en) |
| DE (2) | DE2147316A1 (en) |
| FR (2) | FR2106631B1 (en) |
| GB (2) | GB1351532A (en) |
| NL (2) | NL7112746A (en) |
| SE (2) | SE375090B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887587A (en) * | 1972-04-17 | 1975-06-03 | Pfizer | Synthesis of prostaglandins of the one-series |
-
1971
- 1971-09-15 CA CA122,916,A patent/CA951723A/en not_active Expired
- 1971-09-16 NL NL7112746A patent/NL7112746A/xx unknown
- 1971-09-16 CA CA123,024A patent/CA974987A/en not_active Expired
- 1971-09-17 NL NL7112804A patent/NL7112804A/xx unknown
- 1971-09-17 SE SE1183771A patent/SE375090B/xx unknown
- 1971-09-17 SE SE1183671A patent/SE375089B/xx unknown
- 1971-09-18 DE DE19712147316 patent/DE2147316A1/en active Pending
- 1971-09-18 DE DE19712147315 patent/DE2147315A1/en active Pending
- 1971-09-20 BE BE772837A patent/BE772837A/en unknown
- 1971-09-20 GB GB4380771A patent/GB1351532A/en not_active Expired
- 1971-09-20 FR FR7133684A patent/FR2106631B1/fr not_active Expired
- 1971-09-20 FR FR7133683A patent/FR2106630B1/fr not_active Expired
- 1971-09-20 BE BE772836A patent/BE772836A/en unknown
- 1971-09-20 GB GB4381071A patent/GB1351533A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2106631B1 (en) | 1975-08-01 |
| GB1351533A (en) | 1974-05-01 |
| DE2147315A1 (en) | 1972-03-23 |
| BE772837A (en) | 1972-01-17 |
| CA974987A (en) | 1975-09-23 |
| NL7112746A (en) | 1972-03-21 |
| FR2106631A1 (en) | 1972-05-05 |
| NL7112804A (en) | 1972-03-21 |
| BE772836A (en) | 1972-01-17 |
| FR2106630A1 (en) | 1972-05-05 |
| CA951723A (en) | 1974-07-23 |
| SE375089B (en) | 1975-04-07 |
| SE375090B (en) | 1975-04-07 |
| FR2106630B1 (en) | 1975-08-01 |
| DE2147316A1 (en) | 1972-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |