GB1349136A - Quinazoline derivatives - Google Patents
Quinazoline derivativesInfo
- Publication number
- GB1349136A GB1349136A GB5722170A GB5722170A GB1349136A GB 1349136 A GB1349136 A GB 1349136A GB 5722170 A GB5722170 A GB 5722170A GB 5722170 A GB5722170 A GB 5722170A GB 1349136 A GB1349136 A GB 1349136A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- radical
- compound
- formula
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 3 - Bis - (2 - hydroxyethyl)aminopropylamine dinitrate ester Chemical class 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000003257 anti-anginal effect Effects 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002440 hydroxy compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N nitrate group Chemical group [N+](=O)([O-])[O-] NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- 230000000802 nitrating effect Effects 0.000 abstract 1
- 238000006396 nitration reaction Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87043969A | 1969-12-05 | 1969-12-05 | |
| SE1157870 | 1970-08-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1349136A true GB1349136A (en) | 1974-03-27 |
Family
ID=26655842
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3491073A Expired GB1349140A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivatives |
| GB2616273A Expired GB1349137A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivative |
| GB2616373A Expired GB1349138A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivative |
| GB5722170A Expired GB1349136A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivatives |
| GB3059973A Expired GB1349139A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivatives |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3491073A Expired GB1349140A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivatives |
| GB2616273A Expired GB1349137A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivative |
| GB2616373A Expired GB1349138A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivative |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3059973A Expired GB1349139A (en) | 1969-12-05 | 1970-12-02 | Quinazoline derivatives |
Country Status (17)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030156A1 (en) * | 1979-12-03 | 1981-06-10 | Fujisawa Pharmaceutical Co., Ltd. | Quinazoline derivatives, processes for their preparation and pharmaceutical compositions containing them |
| EP0046572A3 (en) * | 1980-08-20 | 1982-07-14 | Asahi Kasei Kogyo Kabushiki Kaisha | 6-quinazolinesulfonyl derivatives and process for preparation thereof |
| WO2004087120A3 (en) * | 2003-03-29 | 2005-01-27 | Astrazeneca Ab | Use of quinazoline derivatives with src kinase inhibitory activity for the treatment of hypertension |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793371A (fr) * | 1971-12-27 | 1973-06-27 | Sandoz Sa | Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces |
| JPS5416626U (enrdf_load_stackoverflow) * | 1977-07-05 | 1979-02-02 | ||
| WO1995007267A1 (fr) * | 1993-09-10 | 1995-03-16 | Eisai Co., Ltd. | Compose de quinazoline |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1199768A (en) * | 1966-10-31 | 1970-07-22 | Pfizer & Co C | Nitrogen Heterocycles and process for their preparation |
| US3470182A (en) * | 1967-02-09 | 1969-09-30 | Sandoz Ag | 4-amino-substituted quinazolines |
-
0
- BE BE759842D patent/BE759842R/xx active
-
1970
- 1970-11-23 CH CH1519173A patent/CH552601A/xx not_active IP Right Cessation
- 1970-11-23 CH CH1735770A patent/CH549581A/xx unknown
- 1970-12-02 GB GB3491073A patent/GB1349140A/en not_active Expired
- 1970-12-02 GB GB2616273A patent/GB1349137A/en not_active Expired
- 1970-12-02 DE DE19702059164 patent/DE2059164A1/de active Pending
- 1970-12-02 GB GB2616373A patent/GB1349138A/en not_active Expired
- 1970-12-02 GB GB5722170A patent/GB1349136A/en not_active Expired
- 1970-12-02 GB GB3059973A patent/GB1349139A/en not_active Expired
- 1970-12-02 IE IE1541/70A patent/IE34780B1/xx unknown
- 1970-12-03 NL NL7017669A patent/NL7017669A/xx unknown
- 1970-12-03 ES ES0386121A patent/ES386121A1/es not_active Expired
- 1970-12-03 RO RO7000074397A patent/RO62627A/ro unknown
- 1970-12-03 HU HUSA2281A patent/HU162867B/hu unknown
- 1970-12-03 HU HUSA2280A patent/HU162866B/hu unknown
- 1970-12-03 IL IL35779A patent/IL35779A/xx unknown
- 1970-12-03 BG BG016189A patent/BG17598A3/xx unknown
- 1970-12-03 PL PL1970144794A patent/PL81227B1/pl unknown
- 1970-12-03 RO RO7000074396A patent/RO62626A/ro unknown
- 1970-12-04 OA OA54108A patent/OA03536A/xx unknown
- 1970-12-04 SU SU1785908A patent/SU449487A3/ru active
- 1970-12-04 SU SU1785910A patent/SU439091A3/ru active
- 1970-12-04 FR FR7043720A patent/FR2081329B2/fr not_active Expired
- 1970-12-13 BG BG017324A patent/BG17599A3/xx unknown
-
1972
- 1972-04-14 JP JP47037000A patent/JPS4837035B1/ja active Pending
-
1973
- 1973-08-13 AU AU59188/73A patent/AU5918873A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0030156A1 (en) * | 1979-12-03 | 1981-06-10 | Fujisawa Pharmaceutical Co., Ltd. | Quinazoline derivatives, processes for their preparation and pharmaceutical compositions containing them |
| US4377580A (en) | 1979-12-03 | 1983-03-22 | Fujisawa Pharmaceutical Co., Ltd. | Tricyclic quinazoline derivatives |
| US4543356A (en) * | 1979-12-03 | 1985-09-24 | Fujisawa Pharmaceutical Co., Ltd. | Quinazoline derivatives |
| EP0046572A3 (en) * | 1980-08-20 | 1982-07-14 | Asahi Kasei Kogyo Kabushiki Kaisha | 6-quinazolinesulfonyl derivatives and process for preparation thereof |
| WO2004087120A3 (en) * | 2003-03-29 | 2005-01-27 | Astrazeneca Ab | Use of quinazoline derivatives with src kinase inhibitory activity for the treatment of hypertension |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1349140A (en) | 1974-03-27 |
| AU5918873A (en) | 1974-02-14 |
| JPS4837035B1 (enrdf_load_stackoverflow) | 1973-11-08 |
| IE34780B1 (en) | 1975-08-20 |
| HU162867B (enrdf_load_stackoverflow) | 1973-04-28 |
| BG17598A3 (bg) | 1973-11-10 |
| GB1349138A (en) | 1974-03-27 |
| RO62627A (fr) | 1978-05-15 |
| IE34780L (en) | 1971-06-05 |
| FR2081329A2 (enrdf_load_stackoverflow) | 1971-12-03 |
| NL7017669A (enrdf_load_stackoverflow) | 1971-06-08 |
| BE759842R (fr) | 1971-06-03 |
| ES386121A1 (es) | 1973-12-16 |
| CH549581A (de) | 1974-05-31 |
| GB1349139A (en) | 1974-03-27 |
| PL81227B1 (en) | 1975-08-30 |
| FR2081329B2 (enrdf_load_stackoverflow) | 1975-06-06 |
| RO62626A (fr) | 1978-05-15 |
| HU162866B (enrdf_load_stackoverflow) | 1973-04-28 |
| CH552601A (de) | 1974-08-15 |
| SU449487A3 (ru) | 1974-11-05 |
| SU439091A3 (ru) | 1974-08-05 |
| BG17599A3 (bg) | 1973-11-10 |
| DE2059164A1 (de) | 1971-06-09 |
| OA03536A (fr) | 1971-03-30 |
| IL35779A (en) | 1974-06-30 |
| GB1349137A (en) | 1974-03-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI891176A0 (fi) | Peptidfoereningar, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar. | |
| GB1383409A (en) | Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them | |
| GB1461209A (en) | Thienyl and thietyl compounds | |
| GB1260848A (en) | Propanolamine derivatives | |
| GB1247113A (en) | Oxindole carboxamides | |
| GB1302709A (enrdf_load_stackoverflow) | ||
| GB1349136A (en) | Quinazoline derivatives | |
| GB1297386A (enrdf_load_stackoverflow) | ||
| GB1439724A (en) | Berbine derivatives and pharmaceutical compositions containing them | |
| GB1373548A (en) | Anti-hypertensive 6-substituted 3-hydrazino-pyridazines and their preparation | |
| GB1367785A (en) | 2-substituted adenosine derivatives and the production thereof | |
| GB1174051A (en) | Aminophenol Derivatives and Analgesic and Antipyretic Compositions | |
| GB1392551A (en) | Ergolene derivatives their preparation and use | |
| GB1268587A (en) | Phloramine derivatives | |
| GB1358008A (en) | Cephalosporin derivatives | |
| GB1212454A (en) | N,n'-substituted formamidines | |
| GB1246117A (en) | Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture | |
| GB1263116A (en) | Chloramphenicol and thiamphenicol derivatives | |
| GB1322069A (en) | Aminoalkanoylaminocyclohexane derivatives | |
| GB1236078A (en) | Substituted azetidinols | |
| GB1184826A (en) | Substituted Aryloxy Hydroxy Amines | |
| IE35223L (en) | Bis-basic ethers of 2, 6- and 2, 7-dihydroxy-anthraquinones | |
| GB1203430A (en) | Heterocyclic spiro compounds | |
| GB1254270A (en) | Benzoxazepine derivatives | |
| GB1425729A (en) | 1,4-dihydropyridine compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |