GB1333564A - Bridged-ring isoquinoline derivatives - Google Patents
Bridged-ring isoquinoline derivativesInfo
- Publication number
- GB1333564A GB1333564A GB1333564DA GB1333564A GB 1333564 A GB1333564 A GB 1333564A GB 1333564D A GB1333564D A GB 1333564DA GB 1333564 A GB1333564 A GB 1333564A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- bridged
- compounds
- isoquinoline derivatives
- oct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1333564 Bridged-ring isoquinoline derivatives UCB SA 22 Oct 1971 [22 Oct 1970] 50214/70 Heading, C2C The invention comprises (with exceptions as to certain methyl-substituted compounds, as defined in the Specification) compounds of formula wherein R 1 to R 5 are each H, alkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, dialkylamino, alkenyl, aryl or aralkyl, and R 6 is H, halogen, CF 3 , alkyl oralkoxy; each alkyl, alkenyl oralkoxy group containing up to 4 carbon atoms. These compounds are prepared by first forming a compound of formula by Diels-Alder addition of a maleic anhydride to a 3 - oxo - 1,2,3,4 - tetrahydroisoquinoline, hydrolysing it to the corresponding dicarboxylic acid, oxidatively decarboxylating the latter and optionally N-substituting the product (when R 1 =H).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5021470 | 1970-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1333564A true GB1333564A (en) | 1973-10-10 |
Family
ID=10455102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1333564D Expired GB1333564A (en) | 1970-10-22 | 1971-10-22 | Bridged-ring isoquinoline derivatives |
Country Status (13)
| Country | Link |
|---|---|
| BE (1) | BE774240A (en) |
| CA (1) | CA956313A (en) |
| CH (1) | CH541561A (en) |
| DE (1) | DE2152232A1 (en) |
| DK (1) | DK126941B (en) |
| FI (1) | FI49607C (en) |
| GB (1) | GB1333564A (en) |
| HU (1) | HU162914B (en) |
| IT (1) | IT1040524B (en) |
| NL (1) | NL7114352A (en) |
| PL (1) | PL81482B1 (en) |
| SE (1) | SE368201B (en) |
| SU (1) | SU450409A3 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1378403A (en) * | 1972-06-16 | 1974-12-27 | Ucb Sa | Process for the preparation of 3-2h-isoquinolones |
-
1971
- 1971-10-19 NL NL7114352A patent/NL7114352A/xx unknown
- 1971-10-20 DK DK510171A patent/DK126941B/en unknown
- 1971-10-20 DE DE19712152232 patent/DE2152232A1/en active Pending
- 1971-10-21 FI FI296971A patent/FI49607C/en active
- 1971-10-21 BE BE774240A patent/BE774240A/en unknown
- 1971-10-21 SE SE1335471A patent/SE368201B/xx unknown
- 1971-10-21 IT IT5360671A patent/IT1040524B/en active
- 1971-10-21 CA CA125,803A patent/CA956313A/en not_active Expired
- 1971-10-21 CH CH1537371A patent/CH541561A/en not_active IP Right Cessation
- 1971-10-22 SU SU1709505A patent/SU450409A3/en active
- 1971-10-22 HU HUUI000183 patent/HU162914B/hu unknown
- 1971-10-22 PL PL15117571A patent/PL81482B1/pl unknown
- 1971-10-22 GB GB1333564D patent/GB1333564A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK126941B (en) | 1973-09-03 |
| CH541561A (en) | 1973-09-15 |
| PL81482B1 (en) | 1975-08-30 |
| CA956313A (en) | 1974-10-15 |
| SU450409A3 (en) | 1974-11-15 |
| IT1040524B (en) | 1979-12-20 |
| BE774240A (en) | 1972-04-21 |
| HU162914B (en) | 1973-04-28 |
| DE2152232A1 (en) | 1972-04-27 |
| NL7114352A (en) | 1972-04-25 |
| FI49607B (en) | 1975-04-30 |
| FI49607C (en) | 1975-08-11 |
| SE368201B (en) | 1974-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |