GB1319010A - Substituted butyronitriles and a process for the manufacture hereof - Google Patents

Substituted butyronitriles and a process for the manufacture hereof

Info

Publication number
GB1319010A
GB1319010A GB5901671A GB5901671A GB1319010A GB 1319010 A GB1319010 A GB 1319010A GB 5901671 A GB5901671 A GB 5901671A GB 5901671 A GB5901671 A GB 5901671A GB 1319010 A GB1319010 A GB 1319010A
Authority
GB
United Kingdom
Prior art keywords
carbon atoms
butyronitriles
substituted
compounds
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5901671A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1319010A publication Critical patent/GB1319010A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1319010 Substituted butyronitriles F HOFFMANN-LA ROCHE & CO AG 20 Dec 1971 [21 Dec 1970] 59016/71 Heading C2C The invention comprises compounds of the formula where R is H or -CO-Y-COOH, Y is an aliphatic hydrocarbylene group of 2-5 carbon atoms or an arylene group, R<SP>3</SP> is a primary alkyl group of 1-8 carbon atoms or a cycloalkyl group of 3-8 carbon atoms, and addition salts with bases of those compounds in which R is -CO-Y-COOH. The compounds are prepared by reducing the appropriate 4-phenyl- 4-oxo-butyronitrile to give the alcohol which may be esterified with a suitable derivative of a dicarboxylic acid of the formula and subsequently, if desired, reacting the product with an organic base.
GB5901671A 1970-12-21 1971-12-20 Substituted butyronitriles and a process for the manufacture hereof Expired GB1319010A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10037270A 1970-12-21 1970-12-21

Publications (1)

Publication Number Publication Date
GB1319010A true GB1319010A (en) 1973-05-31

Family

ID=22279405

Family Applications (3)

Application Number Title Priority Date Filing Date
GB5901671A Expired GB1319010A (en) 1970-12-21 1971-12-20 Substituted butyronitriles and a process for the manufacture hereof
GB5901771A Expired GB1337790A (en) 1970-12-21 1971-12-20 Pehnolic compounds
GB5901871A Expired GB1317090A (en) 1970-12-21 1971-12-20 Bicyclic compounds and the manufacture thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
GB5901771A Expired GB1337790A (en) 1970-12-21 1971-12-20 Pehnolic compounds
GB5901871A Expired GB1317090A (en) 1970-12-21 1971-12-20 Bicyclic compounds and the manufacture thereof

Country Status (16)

Country Link
AR (2) AR194088A1 (en)
AT (2) AT316520B (en)
AU (2) AU3713171A (en)
BE (2) BE776940A (en)
CA (1) CA1000716A (en)
CH (3) CH586662A5 (en)
DE (3) DE2162801A1 (en)
ES (2) ES398130A1 (en)
FR (3) FR2120818A5 (en)
GB (3) GB1319010A (en)
HU (2) HU164759B (en)
IE (2) IE35904B1 (en)
IL (3) IL38281A (en)
NL (2) NL7117469A (en)
PH (1) PH9548A (en)
ZA (2) ZA718281B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2050825A1 (en) * 1990-09-24 1992-03-25 Pamela M. Simpson Method of making optically active alcohols

Also Published As

Publication number Publication date
HU164613B (en) 1974-03-28
DE2162800A1 (en) 1972-07-06
IL38391A (en) 1975-02-10
AU456833B2 (en) 1975-01-16
IE35905B1 (en) 1976-06-23
PH9548A (en) 1976-01-16
IL38391A0 (en) 1972-02-29
FR2118979A1 (en) 1972-08-04
NL7117495A (en) 1972-06-23
AT316519B (en) 1974-07-10
BE776940A (en) 1972-06-20
CH584706A5 (en) 1977-02-15
GB1337790A (en) 1973-11-21
IL38281A (en) 1974-10-22
IE35905L (en) 1972-06-21
IL38392A0 (en) 1972-02-29
FR2120817A5 (en) 1972-08-18
AT316520B (en) 1974-07-10
IL38281A0 (en) 1972-02-29
ZA718281B (en) 1972-09-27
IE35904B1 (en) 1976-06-23
FR2118979B1 (en) 1974-08-23
ZA718280B (en) 1972-09-27
AR194088A1 (en) 1973-06-22
AU3713171A (en) 1973-06-28
DE2162801A1 (en) 1972-07-06
IE35904L (en) 1972-06-21
NL7117469A (en) 1972-06-23
IL38392A (en) 1975-02-10
BE776939A (en) 1972-06-20
CA1000716A (en) 1976-11-30
CH586662A5 (en) 1977-04-15
DE2162803A1 (en) 1972-07-06
HU164759B (en) 1974-04-11
AR192603A1 (en) 1973-02-28
ES398130A1 (en) 1975-03-16
CH584705A5 (en) 1977-02-15
AU3713271A (en) 1973-06-28
ES398131A1 (en) 1974-07-16
FR2120818A5 (en) 1972-08-18
GB1317090A (en) 1973-05-16

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee