GB1333332A - Trihydroxy-oestratriene derivatives and a process for their manufacture - Google Patents
Trihydroxy-oestratriene derivatives and a process for their manufactureInfo
- Publication number
- GB1333332A GB1333332A GB1042971*[A GB1042971A GB1333332A GB 1333332 A GB1333332 A GB 1333332A GB 1042971 A GB1042971 A GB 1042971A GB 1333332 A GB1333332 A GB 1333332A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- cyclopentyloxy
- prepared
- give
- estratrienes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VHMXMAXPXZLHKX-RUMXQMEISA-N [(9R,10S,13S)-1,2,3,4,5,6,9,10,11,12-decahydrocyclopenta[a]phenanthren-13-yl]methanetriol Chemical class OC([C@@]12C=CC=C1C1=CCC3CCCC[C@@H]3[C@H]1CC2)(O)O VHMXMAXPXZLHKX-RUMXQMEISA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- -1 steroid triols Chemical class 0.000 abstract 5
- BOTLEXFFFSMRLQ-UHFFFAOYSA-N cyclopentyloxycyclopentane Chemical class C1CCCC1OC1CCCC1 BOTLEXFFFSMRLQ-UHFFFAOYSA-N 0.000 abstract 2
- 238000006266 etherification reaction Methods 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- JUAJXSMWFOFDFC-MNHDCVOLSA-N (7r,8r,9s,13s,14s)-3-hydroxy-7,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-one Chemical compound C1C[C@]2(C)C(=O)CC[C@H]2[C@@H]2[C@H](C)CC3=CC(O)=CC=C3[C@H]21 JUAJXSMWFOFDFC-MNHDCVOLSA-N 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- 150000001242 acetic acid derivatives Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000001109 blastomere Anatomy 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- XCIXKGXIYUWCLL-HOSYLAQJSA-N cyclopentanol Chemical class O[13CH]1CCCC1 XCIXKGXIYUWCLL-HOSYLAQJSA-N 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001836 utereotrophic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/168—Steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH622070A CH540243A (de) | 1970-04-24 | 1970-04-24 | Verfahren zur Herstellung eines neuen, östrogen hochwirksamen Steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1333332A true GB1333332A (en) | 1973-10-10 |
Family
ID=4306174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1042971*[A Expired GB1333332A (en) | 1970-04-24 | 1971-04-21 | Trihydroxy-oestratriene derivatives and a process for their manufacture |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT312827B (enExample) |
| CH (2) | CH536296A (enExample) |
| CS (1) | CS157121B2 (enExample) |
| GB (1) | GB1333332A (enExample) |
| SU (1) | SU437279A3 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10159217A1 (de) | 2001-11-27 | 2003-06-05 | Schering Ag | 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate |
-
1970
- 1970-04-24 CH CH1870472A patent/CH536296A/de not_active IP Right Cessation
- 1970-04-24 CH CH622070A patent/CH540243A/de not_active IP Right Cessation
-
1971
- 1971-04-21 GB GB1042971*[A patent/GB1333332A/en not_active Expired
- 1971-04-23 CS CS174073*1A patent/CS157121B2/cs unknown
- 1971-04-23 SU SU1815034A patent/SU437279A3/ru active
- 1971-04-23 AT AT273272A patent/AT312827B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH540243A (de) | 1973-08-15 |
| CH536296A (de) | 1973-04-30 |
| CS157121B2 (enExample) | 1974-08-23 |
| SU437279A3 (ru) | 1974-07-25 |
| AT312827B (de) | 1974-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |