GB1313164A - Blood plasma substitute - Google Patents
Blood plasma substituteInfo
- Publication number
- GB1313164A GB1313164A GB2027970A GB2027970A GB1313164A GB 1313164 A GB1313164 A GB 1313164A GB 2027970 A GB2027970 A GB 2027970A GB 2027970 A GB2027970 A GB 2027970A GB 1313164 A GB1313164 A GB 1313164A
- Authority
- GB
- United Kingdom
- Prior art keywords
- meq
- ions
- gelatin
- blood plasma
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003058 plasma substitute Substances 0.000 title abstract 5
- 229920000159 gelatin Polymers 0.000 abstract 7
- 235000019322 gelatine Nutrition 0.000 abstract 7
- 108010010803 Gelatin Proteins 0.000 abstract 6
- 239000008273 gelatin Substances 0.000 abstract 6
- 235000011852 gelatine desserts Nutrition 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 abstract 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 210000002381 plasma Anatomy 0.000 abstract 2
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 abstract 1
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 abstract 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 abstract 1
- 239000005715 Fructose Substances 0.000 abstract 1
- 229930091371 Fructose Natural products 0.000 abstract 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
- 239000001828 Gelatine Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 229940022663 acetate Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 229940001468 citrate Drugs 0.000 abstract 1
- 125000005442 diisocyanate group Chemical group 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 229940050410 gluconate Drugs 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 235000001727 glucose Nutrition 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229940001447 lactate Drugs 0.000 abstract 1
- 229910001629 magnesium chloride Inorganic materials 0.000 abstract 1
- 235000011147 magnesium chloride Nutrition 0.000 abstract 1
- 229910001425 magnesium ion Inorganic materials 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 108010014241 oxypolygelatine Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 229910001414 potassium ion Inorganic materials 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 235000002639 sodium chloride Nutrition 0.000 abstract 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 1
- 239000001540 sodium lactate Substances 0.000 abstract 1
- 229940005581 sodium lactate Drugs 0.000 abstract 1
- 235000011088 sodium lactate Nutrition 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 229940014800 succinic anhydride Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81997369A | 1969-04-28 | 1969-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1313164A true GB1313164A (en) | 1973-04-11 |
Family
ID=25229569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2027970A Expired GB1313164A (en) | 1969-04-28 | 1970-04-28 | Blood plasma substitute |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2020453A1 (enExample) |
| FR (1) | FR2042381B1 (enExample) |
| GB (1) | GB1313164A (enExample) |
| ZA (1) | ZA702706B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3138094A1 (de) * | 1980-09-25 | 1982-05-06 | Yamanouchi Pharmaceutical Co., Ltd., Tokyo | Mittel zur verbesserung der blutzirkulation |
| US6080538A (en) * | 1993-06-04 | 2000-06-27 | Biotime, Inc. | Plasma like solution and methods of use |
| DE102007047040A1 (de) * | 2007-10-01 | 2009-04-16 | Fresenius Kabi Deutschland Gmbh | Transparentes Kältegel |
| WO2011009797A3 (de) * | 2009-07-20 | 2011-08-25 | B. Braun Melsungen Ag | Plasmaadaptierte und balancierte gelatinelösung |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2746109B1 (fr) * | 1996-03-12 | 1998-04-17 | Rhone Poulenc Rorer Sa | Milieu pour la conservation de materiel biologique |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE455206A (enExample) * | ||||
| GB886553A (en) * | 1958-01-22 | 1962-01-10 | Hoechst Ag | Substitutes for blood plasma and process for their manufacture |
-
1970
- 1970-04-22 ZA ZA702706A patent/ZA702706B/xx unknown
- 1970-04-27 DE DE19702020453 patent/DE2020453A1/de active Pending
- 1970-04-28 FR FR7015529A patent/FR2042381B1/fr not_active Expired
- 1970-04-28 GB GB2027970A patent/GB1313164A/en not_active Expired
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3138094A1 (de) * | 1980-09-25 | 1982-05-06 | Yamanouchi Pharmaceutical Co., Ltd., Tokyo | Mittel zur verbesserung der blutzirkulation |
| US6080538A (en) * | 1993-06-04 | 2000-06-27 | Biotime, Inc. | Plasma like solution and methods of use |
| US6387612B1 (en) * | 1993-06-04 | 2002-05-14 | Biotime, Inc. | Method of preparing a terminally heat sterilized plasma-like solution |
| US6406839B1 (en) | 1993-06-04 | 2002-06-18 | Biotime, Inc. | Methods for using a plasma-like solution |
| US6410218B2 (en) * | 1993-06-04 | 2002-06-25 | Biotime, Inc. | Plasma-like solution |
| US6444418B2 (en) * | 1993-06-04 | 2002-09-03 | Biotime, Inc. | Plasma-like solution |
| DE102007047040A1 (de) * | 2007-10-01 | 2009-04-16 | Fresenius Kabi Deutschland Gmbh | Transparentes Kältegel |
| US8865397B2 (en) | 2007-10-01 | 2014-10-21 | Fresenius Kabi Deutschland Gmbh | Method for cooling an organ with a transparent cooling gel |
| WO2011009797A3 (de) * | 2009-07-20 | 2011-08-25 | B. Braun Melsungen Ag | Plasmaadaptierte und balancierte gelatinelösung |
| CN102470147A (zh) * | 2009-07-20 | 2012-05-23 | 布朗·B·梅尔松根股份公司 | 适用于血浆的平衡明胶溶液 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2042381B1 (enExample) | 1974-02-01 |
| FR2042381A1 (enExample) | 1971-02-12 |
| DE2020453A1 (de) | 1970-11-12 |
| ZA702706B (en) | 1971-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |