GB1310245A - Blood testing - Google Patents

Blood testing

Info

Publication number
GB1310245A
GB1310245A GB1325170A GB1325170A GB1310245A GB 1310245 A GB1310245 A GB 1310245A GB 1325170 A GB1325170 A GB 1325170A GB 1325170 A GB1325170 A GB 1325170A GB 1310245 A GB1310245 A GB 1310245A
Authority
GB
United Kingdom
Prior art keywords
membrane
blood
plunger
elements
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1325170A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromedic Systems Inc
Original Assignee
Micromedic Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromedic Systems Inc filed Critical Micromedic Systems Inc
Publication of GB1310245A publication Critical patent/GB1310245A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G04—HOROLOGY
    • G04F—TIME-INTERVAL MEASURING
    • G04F8/00—Apparatus for measuring unknown time intervals by electromechanical means
    • G04F8/006—Apparatus for measuring unknown time intervals by electromechanical means running only during the time interval to be measured, e.g. stop-watch

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)

Abstract

1310245 Device for blood coagulation tests MICROMEDIC SYSTEMS Inc 19 March 1970 [19 March 1969] 13251/70 Heading B1X [Also in Division B8] A device for use in blood coagulation tests comprises (Fig. 1) a tubular test chamber divided into two compartments by a rupturable membrane 2d, one compartment (below the membrane as shown) containing an aqueous solution containing calcium ions and the other compartment containing a suspension of a blood coagulation factor, for example thromboplastin in a solution of blood anticoagulant, the device being openable as by separation of parts 1 and 2 to permit introduction of sample into the suspension of coagulation factor, and also comprising means for example plunger 3 for rupturing membrane 2d to allow mixing of the sample and test reagents. The embodiment shown in Fig. 1 comprises engageable tubular elements 1, 2 of polyethylene or polypropylene, the internal surfaces of the adjoining parts of elements 1, 2 being ribbed as at 2L, in element 1 a square cross-section rod 3 having a cylindrical recess 3c and secured by a frusto conical portion 3a to a burstable membrane 1d, in element 2 a disc 4 having a protruding peg 4a for engagement with recess 3c, disc 4 being secured to burstable membrane 2d which separates the two compartments and disc 5 force-fitted in position 2e. In use, elements 1 and 2 are separated (with the device inverted) and blood is introduced into portion L2 (Fig. 1) up to the tip of peg 4a. Elements 1 and 2 are reassembled and the device shaken to mix the blood with the anticoagulant solution. The device may then be stored, or the test continued. For the test, the device is heated to 37‹C, then element 2 is fitted over boss 7 (Fig. 5) and pressure applied on plunger 3 by means 8 to move the plunger to break first membrane 1d (Fig. 6 not shown) then membrane 2d (Fig. 7). The coagulation time of the blood is then measured. The device may be used in conjunction with the apparatus of Specification 1310246. In an alternative embodiment, plunger 3 is kept stationary and the device moved upwardly against the plunger by means of mandrel 10 (Figs. 8-10 not shown). Mandrel 10 is rotated and pin 81 kept stationary in measuring the coagulation time.
GB1325170A 1969-03-19 1970-03-19 Blood testing Expired GB1310245A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH412469A CH506791A (en) 1969-03-19 1969-03-19 Device for carrying out a blood coagulation test and method of activating this device

Publications (1)

Publication Number Publication Date
GB1310245A true GB1310245A (en) 1973-03-14

Family

ID=4270265

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1325170A Expired GB1310245A (en) 1969-03-19 1970-03-19 Blood testing
GB1325270A Expired GB1310246A (en) 1969-03-19 1970-03-19 Automatic blood testing

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1325270A Expired GB1310246A (en) 1969-03-19 1970-03-19 Automatic blood testing

Country Status (10)

Country Link
US (2) US3692487A (en)
AU (1) AU1283570A (en)
CH (2) CH533307A (en)
DE (2) DE2014123A1 (en)
ES (1) ES377637A1 (en)
FR (2) FR2039644A5 (en)
GB (2) GB1310245A (en)
IL (2) IL34113A0 (en)
NL (2) NL7003917A (en)
ZA (1) ZA701872B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951606A (en) * 1974-05-17 1976-04-20 Geomet, Inc. Apparatus for prothrombin testing
US3918908A (en) * 1974-05-17 1975-11-11 Geomet Method for prothrombin testing
US4000972A (en) * 1976-01-16 1977-01-04 Hemotec, Inc. Measuring system for the pharmacological manipulation of the coagulation mechanism in blood and for the elapsed coagulation time
US4262521A (en) * 1979-08-27 1981-04-21 Sperry Corporation Epoxy resin gel tester
LU84191A1 (en) * 1981-06-12 1982-12-13 Ferrero Spa CONTAINER FOR BEVERAGE PERFORABLE BY A STRAW
US4663127A (en) * 1982-10-15 1987-05-05 Hemotec, Inc. Gas flow cartridge having resilient flexible membrane with slit separating reaction and reagent chambers
US4533519A (en) * 1983-07-20 1985-08-06 Hemotec, Inc. Gas flow coagulation test cartridge having movable member establishing communication between reagent and reaction chambers
US4797369A (en) * 1985-04-05 1989-01-10 International Technidyne Corp. Method and apparatus for detecting a blood clot
US4947679A (en) * 1989-04-21 1990-08-14 The Dow Chemical Company Apparatus for determining resin gel time
US5174961A (en) * 1991-01-18 1992-12-29 Hemotec, Inc. High sensitivity coagulation detection apparatus
US5314826A (en) * 1991-08-23 1994-05-24 Medtronic Hemotec, Inc. Platelet activation and function evaluation technique
US5302348A (en) * 1992-12-10 1994-04-12 Itc Corporation Blood coagulation time test apparatus and method
US5925319A (en) 1996-04-30 1999-07-20 Medtronic, Inc. Test cartridge for evaluating blood platelet functionality
US6746872B2 (en) 2002-01-16 2004-06-08 Lifescan, Inc. Control compositions and methods of use for coagulation tests
WO2005116623A2 (en) * 2004-05-17 2005-12-08 Medtronic, Inc. Point of care heparin determination system
US10823743B1 (en) 2013-10-28 2020-11-03 Ifirst Medical Technologies, Inc. Methods of measuring coagulation of a biological sample
EP3217168A1 (en) 2016-03-08 2017-09-13 Roche Diagnostics GmbH Test element analysis system for the analytical examination of a sample
RU2645081C1 (en) * 2016-12-28 2018-02-15 Анна Николаевна Плаксина Coagulation analyzer - thromboelastograph
JP7313332B2 (en) * 2017-07-27 2023-07-24 ビオメリュー・インコーポレイテッド isolation tube
CN110583628B (en) * 2019-10-11 2021-08-24 山东山大附属生殖医院有限公司 Biological cell refrigerating device convenient to search
CN115253987B (en) * 2022-09-26 2022-12-09 山东新港化工有限公司 Surfactant neutralization auxiliary device for oil displacement and use method

Also Published As

Publication number Publication date
US3704099A (en) 1972-11-28
IL34114A0 (en) 1970-05-21
IL34113A0 (en) 1970-05-21
DE2014133A1 (en) 1970-10-01
FR2039644A5 (en) 1971-01-15
CH506791A (en) 1971-04-30
DE2014123A1 (en) 1970-10-08
NL7003916A (en) 1970-09-22
ES377637A1 (en) 1972-07-16
GB1310246A (en) 1973-03-14
US3692487A (en) 1972-09-19
ZA701872B (en) 1971-05-27
CH533307A (en) 1973-01-31
NL7003917A (en) 1970-09-22
FR2039643A5 (en) 1971-01-15
AU1283570A (en) 1971-09-23

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed