GB1308656A - Cardadienolide derivatives and process for their manufacture - Google Patents
Cardadienolide derivatives and process for their manufactureInfo
- Publication number
- GB1308656A GB1308656A GB2247370A GB2247370A GB1308656A GB 1308656 A GB1308656 A GB 1308656A GB 2247370 A GB2247370 A GB 2247370A GB 2247370 A GB2247370 A GB 2247370A GB 1308656 A GB1308656 A GB 1308656A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxo
- derivatives
- dienolide
- chloro
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PGKJNAXCLTZKDU-UHFFFAOYSA-N 14-hydroxy-11-methoxy-3-oxo-11,19-epoxycarda-4,20(22)-dienolide Chemical class C1CC2(O)C(C34)CCC5=CC(=O)CCC54COC3(OC)CC2(C)C1C1=CC(=O)OC1 PGKJNAXCLTZKDU-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691924801 DE1924801A1 (de) | 1969-05-14 | 1969-05-14 | Verfahren zur Herstellung von 4-Chlor-3-oxo-14beta-hydroxy- bzw. 4-Chlor-3,14beta-dihydroxy-carda-4,20(22)-dienoliden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1308656A true GB1308656A (en) | 1973-02-21 |
Family
ID=5734258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2247370A Expired GB1308656A (en) | 1969-05-14 | 1970-05-14 | Cardadienolide derivatives and process for their manufacture |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3674779A (OSRAM) |
| AT (1) | AT315388B (OSRAM) |
| BE (1) | BE750418A (OSRAM) |
| CA (1) | CA919168A (OSRAM) |
| DE (1) | DE1924801A1 (OSRAM) |
| DK (1) | DK126190B (OSRAM) |
| FR (1) | FR2051529B1 (OSRAM) |
| GB (1) | GB1308656A (OSRAM) |
| NL (1) | NL7006927A (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2003315B2 (de) * | 1970-01-26 | 1978-05-18 | Hoechst Ag, 6000 Frankfurt | Herzwirksame Pyranoside von 3 ß- Hydroxy-4chlor-carda-4,20(22)-dienoliden, Verfahren zu ihrer Herstellung sowie ihre Verwendung bei der Bekämpfung von Herz- und Kreislaufkrankheiten |
-
1969
- 1969-05-14 DE DE19691924801 patent/DE1924801A1/de active Pending
-
1970
- 1970-05-08 US US35895A patent/US3674779A/en not_active Expired - Lifetime
- 1970-05-13 DK DK243470AA patent/DK126190B/da unknown
- 1970-05-13 NL NL7006927A patent/NL7006927A/xx unknown
- 1970-05-14 GB GB2247370A patent/GB1308656A/en not_active Expired
- 1970-05-14 BE BE750418D patent/BE750418A/xx unknown
- 1970-05-14 FR FR707017604A patent/FR2051529B1/fr not_active Expired
- 1970-05-14 AT AT436370A patent/AT315388B/de active
- 1970-05-14 CA CA082734A patent/CA919168A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2051529A1 (OSRAM) | 1971-04-09 |
| NL7006927A (OSRAM) | 1970-11-17 |
| BE750418A (fr) | 1970-11-16 |
| DK126190B (da) | 1973-06-18 |
| DE1924801A1 (de) | 1970-11-19 |
| AT315388B (de) | 1974-05-27 |
| FR2051529B1 (OSRAM) | 1973-08-10 |
| US3674779A (en) | 1972-07-04 |
| CA919168A (en) | 1973-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |