GB1307436A - Styrene derivatives - Google Patents
Styrene derivativesInfo
- Publication number
- GB1307436A GB1307436A GB3766370A GB3766370A GB1307436A GB 1307436 A GB1307436 A GB 1307436A GB 3766370 A GB3766370 A GB 3766370A GB 3766370 A GB3766370 A GB 3766370A GB 1307436 A GB1307436 A GB 1307436A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- reacting
- alkyl
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000003011 styrenyl group Chemical class [H]\C(*)=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 13
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- -1 2-quinolyl Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004174 2-benzimidazolyl group Chemical group [H]N1C(*)=NC2=C([H])C([H])=C([H])C([H])=C12 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000004307 pyrazin-2-yl group Chemical group [H]C1=C([H])N=C(*)C([H])=N1 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 150000003440 styrenes Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/18—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring
- C07C39/19—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with unsaturation outside the aromatic ring containing carbon-to-carbon double bonds but no carbon-to-carbon triple bonds
- C07C39/20—Hydroxy-styrenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Illuminated Signs And Luminous Advertising (AREA)
Abstract
1307436 Styrenes DR KARL THOMAE GmbH 4 Aug 1970 [5 Aug 1969] 37663/70 Heading C2C Compounds of the general Formula (I): (Ar=2-, 3- or 4-pyridyl, 2-quinolyl, 2-pyrazinyl, pyrimidyl or 5-(1,2,4-oxadiazolyl) optionally substituted by a C l -y alkyl group, 2-benzimidazolyl optionally substituted by a halogen atom or a OF or C 1-3 alkyl group, 5-isoxazolyl optionally substituted by a Ph or C 1-3 alkyl group, Ph, 2-furyl, 2-thienyl; R 1,2,4,5 = H, C 1-3 alkyl; R3 = H, C 1-3 alkoxy; R 6,7 =H, C 1-3 alkyl, alkenyl, hydroxyalkyl, alkoxyalkyl, aralkyl or NR 6 R 7 = saturated monocyclic 5-7 membered ring optionally containing an oxygen or further nitrogen atom; n = 0, 1) and their acid addition salts, are prepared by (a) eliminating water from a compound of the Formula (II): (b) reacting a compound of the Formula (III): (R 8 = C 1-3 alkyl) with a compound of the Formula (IV): in the presence of a base, (c) reacting a compound of the Formula (V): with a compound of the Formula (VI): in the presence of a base, (d) reacting a compound of the Formula (VII): (X=H, COCH 3 ) with a compound of the Formula (VIII): (Y=halogen) in the presence of a base, (e) reacting a compound of the Formula (IX):) (Z = replaceable atom or group) with a compound of the Formula (X): or (f) reacting a compound of the Formula (XI): with a compound of the Formula (IV), optionally followed in each case by salt formation and/ or isomer separation. The above compounds are analgesics, sedatives, and muscle relaxants, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1939809A DE1939809B2 (en) | 1969-08-05 | 1969-08-05 | β-Aryl-2-aminoalkoxy-styrenes and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1307436A true GB1307436A (en) | 1973-02-21 |
Family
ID=5741970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3766370A Expired GB1307436A (en) | 1969-08-05 | 1970-08-04 | Styrene derivatives |
Country Status (25)
| Country | Link |
|---|---|
| JP (6) | JPS4941433B1 (en) |
| KR (1) | KR780000113B1 (en) |
| AT (5) | AT301565B (en) |
| BE (1) | BE754405A (en) |
| BG (6) | BG18600A3 (en) |
| CH (6) | CH548982A (en) |
| CS (6) | CS170537B2 (en) |
| DE (1) | DE1939809B2 (en) |
| DK (1) | DK139717B (en) |
| ES (6) | ES382428A1 (en) |
| FI (1) | FI54912C (en) |
| FR (1) | FR2068463B1 (en) |
| GB (1) | GB1307436A (en) |
| HU (1) | HU163185B (en) |
| IE (1) | IE34634B1 (en) |
| IL (1) | IL35047A (en) |
| NL (1) | NL7011590A (en) |
| NO (1) | NO135243C (en) |
| PH (1) | PH9520A (en) |
| PL (2) | PL78370B1 (en) |
| RO (5) | RO57793A (en) |
| SE (1) | SE382211B (en) |
| SU (4) | SU432712A3 (en) |
| YU (2) | YU198170A (en) |
| ZA (1) | ZA705411B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0004066A1 (en) * | 1978-03-09 | 1979-09-19 | Mitsubishi Kasei Corporation | 2-(4-aminobutoxy)stilbenes and pharmaceutical compositions containing these substances |
| US4237278A (en) | 1978-04-28 | 1980-12-02 | Basf Aktiengesellschaft | Amino derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole |
| US4251539A (en) * | 1978-04-29 | 1981-02-17 | Basf Aktiengesellschaft | Amino derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazoles |
| US4305951A (en) | 1979-10-26 | 1981-12-15 | Basf Aktiengesellschaft | Novel amino derivatives of 5-(2-hydroxystyryl)-isoxazole, their preparation and therapeutic formulations containing these compounds |
| US4353917A (en) | 1979-10-26 | 1982-10-12 | Basf Aktiengesellschaft | Amino derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole, their preparation, and formulations containing these compounds |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50139537A (en) * | 1974-04-25 | 1975-11-07 | ||
| US4220603A (en) * | 1977-10-07 | 1980-09-02 | Mitsubishi Chemical Industries, Limited | Pharmaceutically active (omega-aminoalkoxy)bibenzyls |
| DE2818998A1 (en) * | 1978-04-29 | 1979-11-15 | Basf Ag | 3-ALKYL-5- (2-HYDROXY-STYRYL) -ISOXAZOLES AND METHOD FOR THE PRODUCTION THEREOF |
| JPS5629548A (en) * | 1979-08-16 | 1981-03-24 | Mitsubishi Chem Ind Ltd | Omega-aminoalkoxystilbenes and their acid addition salts |
| DE3006809A1 (en) * | 1980-02-23 | 1981-09-24 | Basf Ag, 6700 Ludwigshafen | 2 - ((3-AMINO-2-HYDROXY-PROPOXY) -STYRYL) -ISOXAZOLES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| JPS5874379U (en) * | 1981-11-16 | 1983-05-19 | 富士通株式会社 | electronic equipment |
| NO174506B (en) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogous procedure for the preparation of therapeutically active compounds |
| MX2013014588A (en) | 2011-06-10 | 2014-01-24 | Procter & Gamble | Absorbent structure for absorbent articles. |
| CN105816277A (en) | 2011-06-10 | 2016-08-03 | 宝洁公司 | Disposable diapers |
| RU2013156991A (en) | 2011-06-10 | 2015-07-20 | Дзе Проктер Энд Гэмбл Компани | ABSORBING HEART FOR DISPOSABLE ABSORBING PRODUCTS |
| EP2740449B1 (en) | 2012-12-10 | 2019-01-23 | The Procter & Gamble Company | Absorbent article with high absorbent material content |
| ES2655690T3 (en) | 2013-06-14 | 2018-02-21 | The Procter & Gamble Company | Absorbent article and absorbent core formation channels when wet |
| US9987176B2 (en) | 2013-08-27 | 2018-06-05 | The Procter & Gamble Company | Absorbent articles with channels |
| EP3351225B1 (en) | 2013-09-19 | 2021-12-29 | The Procter & Gamble Company | Absorbent cores having material free areas |
| PL2886092T3 (en) | 2013-12-19 | 2017-03-31 | The Procter And Gamble Company | Absorbent cores having channel-forming areas and c-wrap seals |
-
0
- BE BE754405D patent/BE754405A/en unknown
-
1969
- 1969-08-05 DE DE1939809A patent/DE1939809B2/en active Granted
-
1970
- 1970-07-21 FI FI2035/70A patent/FI54912C/en active
- 1970-07-22 RO RO65938A patent/RO57793A/ro unknown
- 1970-07-22 RO RO65491A patent/RO58861A2/en unknown
- 1970-07-22 BG BG017594A patent/BG18600A3/en unknown
- 1970-07-22 BG BG015253A patent/BG18599A3/en unknown
- 1970-07-22 BG BG017596A patent/BG17950A3/en unknown
- 1970-07-22 RO RO65939A patent/RO57794A/ro unknown
- 1970-07-22 BG BG017595A patent/BG20095A3/en unknown
- 1970-07-22 BG BG017598A patent/BG17952A3/en unknown
- 1970-07-22 RO RO64019A patent/RO57548A/ro unknown
- 1970-07-22 RO RO65937A patent/RO58837A/ro unknown
- 1970-07-22 BG BG017597A patent/BG17951A3/en unknown
- 1970-07-28 SU SU1701181A patent/SU432712A3/ru active
- 1970-07-28 SU SU1700804A patent/SU439965A3/en active
- 1970-07-28 SU SU1701190A patent/SU450398A3/en active
- 1970-07-28 SU SU1701179A patent/SU428597A3/en active
- 1970-07-30 KR KR7001068A patent/KR780000113B1/en active
- 1970-07-31 CS CS3513*[A patent/CS170537B2/cs unknown
- 1970-07-31 CS CS5391A patent/CS170533B2/cs unknown
- 1970-07-31 CS CS3511*[A patent/CS170535B2/cs unknown
- 1970-07-31 CS CS3510*[A patent/CS170534B2/cs unknown
- 1970-07-31 CS CS3514*[A patent/CS170538B2/cs unknown
- 1970-07-31 CS CS3512*[A patent/CS170536B2/cs unknown
- 1970-08-03 JP JP45067958A patent/JPS4941433B1/ja active Pending
- 1970-08-03 HU HUTO819A patent/HU163185B/hu unknown
- 1970-08-04 ES ES382428A patent/ES382428A1/en not_active Expired
- 1970-08-04 CH CH148173A patent/CH548982A/en not_active IP Right Cessation
- 1970-08-04 ES ES382429A patent/ES382429A1/en not_active Expired
- 1970-08-04 CH CH148273A patent/CH548983A/en not_active IP Right Cessation
- 1970-08-04 YU YU01981/70A patent/YU198170A/en unknown
- 1970-08-04 DK DK401270AA patent/DK139717B/en unknown
- 1970-08-04 GB GB3766370A patent/GB1307436A/en not_active Expired
- 1970-08-04 CH CH147873A patent/CH548981A/en not_active IP Right Cessation
- 1970-08-04 CH CH148073A patent/CH548368A/en not_active IP Right Cessation
- 1970-08-04 PH PH11713*UA patent/PH9520A/en unknown
- 1970-08-04 PL PL1970142516A patent/PL78370B1/pl unknown
- 1970-08-04 ES ES382427A patent/ES382427A1/en not_active Expired
- 1970-08-04 IL IL35047A patent/IL35047A/en unknown
- 1970-08-04 IE IE998/70A patent/IE34634B1/en unknown
- 1970-08-04 ES ES382430A patent/ES382430A1/en not_active Expired
- 1970-08-04 CH CH147973A patent/CH548367A/en not_active IP Right Cessation
- 1970-08-04 PL PL1970175377A patent/PL93130B1/pl unknown
- 1970-08-04 NO NO3005/70A patent/NO135243C/no unknown
- 1970-08-04 CH CH1172670A patent/CH548366A/en not_active IP Right Cessation
- 1970-08-04 ES ES382425A patent/ES382425A1/en not_active Expired
- 1970-08-04 ES ES382426A patent/ES382426A1/en not_active Expired
- 1970-08-05 FR FR7028941A patent/FR2068463B1/fr not_active Expired
- 1970-08-05 AT AT713970A patent/AT301565B/en not_active IP Right Cessation
- 1970-08-05 ZA ZA705411A patent/ZA705411B/en unknown
- 1970-08-05 SE SE7010773A patent/SE382211B/en unknown
- 1970-08-05 AT AT943371A patent/AT302346B/en not_active IP Right Cessation
- 1970-08-05 AT AT943271A patent/AT303055B/en not_active IP Right Cessation
- 1970-08-05 NL NL7011590A patent/NL7011590A/xx not_active Application Discontinuation
- 1970-08-05 AT AT943171A patent/AT302345B/en not_active IP Right Cessation
- 1970-08-05 AT AT943071A patent/AT302344B/en not_active IP Right Cessation
-
1973
- 1973-11-29 JP JP48133940A patent/JPS5113149B1/ja active Pending
- 1973-11-29 JP JP48133939A patent/JPS5113148B1/ja active Pending
- 1973-11-29 JP JP48133937A patent/JPS5113146B1/ja active Pending
- 1973-11-29 JP JP48133941A patent/JPS5113150B1/ja active Pending
- 1973-11-29 JP JP48133938A patent/JPS5113147B1/ja active Pending
-
1978
- 1978-02-17 YU YU00374/78A patent/YU37478A/en unknown
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0004066A1 (en) * | 1978-03-09 | 1979-09-19 | Mitsubishi Kasei Corporation | 2-(4-aminobutoxy)stilbenes and pharmaceutical compositions containing these substances |
| US4237278A (en) | 1978-04-28 | 1980-12-02 | Basf Aktiengesellschaft | Amino derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole |
| US4251539A (en) * | 1978-04-29 | 1981-02-17 | Basf Aktiengesellschaft | Amino derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazoles |
| US4305951A (en) | 1979-10-26 | 1981-12-15 | Basf Aktiengesellschaft | Novel amino derivatives of 5-(2-hydroxystyryl)-isoxazole, their preparation and therapeutic formulations containing these compounds |
| US4353917A (en) | 1979-10-26 | 1982-10-12 | Basf Aktiengesellschaft | Amino derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole, their preparation, and formulations containing these compounds |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |