GB1297835A - - Google Patents

Info

Publication number

GB1297835A

GB1297835A GB1297835DA GB1297835A GB 1297835 A GB1297835 A GB 1297835A GB 1297835D A GB1297835D A GB 1297835DA GB 1297835 A GB1297835 A GB 1297835A

Authority

GB

United Kingdom

Prior art keywords

acid

formula

cyclohexadienyl

hydrolysis

acetamido

Prior art date

1970-08-18

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired

Links

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• -1 Cyclohexadienyl penicillins Chemical class 0.000 abstract 3
• 230000007062 hydrolysis Effects 0.000 abstract 3
• 238000006460 hydrolysis reaction Methods 0.000 abstract 3
• 229930182555 Penicillin Natural products 0.000 abstract 2
• DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 2
• 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 2
• 239000002253 acid Substances 0.000 abstract 2
• 238000006243 chemical reaction Methods 0.000 abstract 2
• FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
• ITAMCOCNZJPJDF-UHFFFAOYSA-N 1-(6-aminopurin-9-yl)propan-2-yloxymethyl-phenoxyphosphinic acid Chemical compound C1=NC2=C(N)N=CN=C2N1CC(C)OCP(O)(=O)OC1=CC=CC=C1 ITAMCOCNZJPJDF-UHFFFAOYSA-N 0.000 abstract 1
• UNMUHJDZLZDXIY-UHFFFAOYSA-N 2-cyclohexa-1,4-dien-1-yl-3-oxo-3-phenoxypropanoic acid Chemical compound C1(=CC=CC=C1)OC(C(C(=O)O)C1=CCC=CC1)=O UNMUHJDZLZDXIY-UHFFFAOYSA-N 0.000 abstract 1
• SNJPAJFYHBEEBD-UHFFFAOYSA-N 2-cyclohexa-1,4-dien-1-ylpropanedioic acid Chemical compound OC(=O)C(C(O)=O)C1=CCC=CC1 SNJPAJFYHBEEBD-UHFFFAOYSA-N 0.000 abstract 1
• NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
• NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
• QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
• WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
• ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
• 150000008064 anhydrides Chemical class 0.000 abstract 1
• 150000001540 azides Chemical class 0.000 abstract 1
• 229910021538 borax Inorganic materials 0.000 abstract 1
• 150000001875 compounds Chemical class 0.000 abstract 1
• 150000004820 halides Chemical class 0.000 abstract 1
• 229910052744 lithium Inorganic materials 0.000 abstract 1
• 150000002690 malonic acid derivatives Chemical class 0.000 abstract 1
• 231100000252 nontoxic Toxicity 0.000 abstract 1
• 230000003000 nontoxic effect Effects 0.000 abstract 1
• RBKMMJSQKNKNEV-RITPCOANSA-N penicillanic acid Chemical compound OC(=O)[C@H]1C(C)(C)S[C@@H]2CC(=O)N21 RBKMMJSQKNKNEV-RITPCOANSA-N 0.000 abstract 1
• 150000002960 penicillins Chemical class 0.000 abstract 1
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
• WWYDYZMNFQIYPT-UHFFFAOYSA-N ru78191 Chemical compound OC(=O)C(C(O)=O)C1=CC=CC=C1 WWYDYZMNFQIYPT-UHFFFAOYSA-N 0.000 abstract 1
• 150000003839 salts Chemical class 0.000 abstract 1
• 239000004328 sodium tetraborate Substances 0.000 abstract 1
• 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1