GB1286603A - 2-substituted polyhalobenzimidazoles - Google Patents
2-substituted polyhalobenzimidazolesInfo
- Publication number
- GB1286603A GB1286603A GB44896/70A GB4489670A GB1286603A GB 1286603 A GB1286603 A GB 1286603A GB 44896/70 A GB44896/70 A GB 44896/70A GB 4489670 A GB4489670 A GB 4489670A GB 1286603 A GB1286603 A GB 1286603A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- alkyl
- halo
- csnh
- tri
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 2-thiazolin-2-yl Chemical group 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- GGJAWSFVEAEROC-UHFFFAOYSA-N 4,5,6-trichloro-1,3-dihydrobenzimidazole-2-thione Chemical compound ClC=1C(=C(C2=C(N=C(N2)S)C1)Cl)Cl GGJAWSFVEAEROC-UHFFFAOYSA-N 0.000 abstract 1
- WBBXODCLEOLLHN-UHFFFAOYSA-N 4,5,7-trichlorobenzimidazol-2-one Chemical compound ClC1=C(C=C(C2=NC(N=C21)=O)Cl)Cl WBBXODCLEOLLHN-UHFFFAOYSA-N 0.000 abstract 1
- LDNCXIVKUFSLBX-UHFFFAOYSA-N 4,6,7-trichloro-2-(2-phenylethenyl)-1H-benzimidazole Chemical class C(=CC1=CC=CC=C1)C=1NC2=C(N1)C(=CC(=C2Cl)Cl)Cl LDNCXIVKUFSLBX-UHFFFAOYSA-N 0.000 abstract 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000008065 acid anhydrides Chemical class 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001165 anti-coccidial effect Effects 0.000 abstract 1
- 150000001556 benzimidazoles Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000005111 carboxyalkoxy group Chemical group 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 150000004965 peroxy acids Chemical class 0.000 abstract 1
- 230000000361 pesticidal effect Effects 0.000 abstract 1
- MNWBNISUBARLIT-UHFFFAOYSA-N sodium cyanide Chemical compound [Na+].N#[C-] MNWBNISUBARLIT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/22—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86145269A | 1969-09-26 | 1969-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1286603A true GB1286603A (en) | 1972-08-23 |
Family
ID=25335828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB44896/70A Expired GB1286603A (en) | 1969-09-26 | 1970-09-21 | 2-substituted polyhalobenzimidazoles |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4932535B1 (enrdf_load_stackoverflow) |
| CA (1) | CA950468A (enrdf_load_stackoverflow) |
| CH (1) | CH556341A (enrdf_load_stackoverflow) |
| DE (1) | DE2047369A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2070090B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1286603A (enrdf_load_stackoverflow) |
| IL (1) | IL35291A0 (enrdf_load_stackoverflow) |
| NL (1) | NL7013343A (enrdf_load_stackoverflow) |
| ZA (1) | ZA706553B (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0219192A3 (en) * | 1985-08-08 | 1987-06-24 | Schering Agrochemicals Limited | Fungicides |
| US5482956A (en) * | 1992-11-06 | 1996-01-09 | Bayer Aktiengesellschaft | Method of treating parastic protozoa with substituted benzimidazoles |
| WO2011058139A1 (en) * | 2009-11-12 | 2011-05-19 | Selvita Sp. Z O. O. | A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
| US8604217B2 (en) | 2009-11-12 | 2013-12-10 | Selvita S.A. | Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50137570A (enrdf_load_stackoverflow) * | 1974-04-18 | 1975-10-31 | ||
| JPS5139426U (enrdf_load_stackoverflow) * | 1974-09-18 | 1976-03-24 | ||
| JPS5175327A (enrdf_load_stackoverflow) * | 1974-12-25 | 1976-06-29 | Fujitsu Ltd | |
| LU75684A1 (enrdf_load_stackoverflow) * | 1976-08-27 | 1978-04-13 | ||
| IL54474A (en) * | 1977-04-12 | 1982-04-30 | Ciba Geigy Ag | Benzimidazole derivatives,their preparation and anthelmintic compositions containing them |
| FR2521141A1 (fr) * | 1982-02-09 | 1983-08-12 | Rhone Poulenc Agrochimie | Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides |
| FR2601010A1 (fr) * | 1986-07-02 | 1988-01-08 | Rhone Poulenc Agrochimie | Derives de sulfonyl benzimidazole, leur preparation ainsi que leur utilisation a titre de fongicides |
| FR2607811A1 (fr) * | 1986-12-05 | 1988-06-10 | Rhone Poulenc Agrochimie | Derives de sulfonyl benzimidazole, leur preparation ainsi que leur utilisation a titre de fongicides |
| DE4237567A1 (de) * | 1992-11-06 | 1994-05-11 | Bayer Ag | Schädlingsbekämpfungsmittel |
| DE4242183A1 (de) * | 1992-12-15 | 1994-06-16 | Bayer Ag | Verwendung von CN-substituierten Benzimidazolen |
| DE4416116A1 (de) * | 1994-05-06 | 1995-11-09 | Bayer Ag | Substituierte Benzimidazole |
| DE19920551A1 (de) * | 1999-05-05 | 2000-11-09 | Bayer Ag | Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen |
| DE10131149A1 (de) * | 2001-06-28 | 2003-01-16 | Bayer Ag | Substituierte Benzinmidazole zur Bekämpfung von Endoparasiten |
| DE102009038950A1 (de) | 2009-08-26 | 2011-03-03 | Bayer Animal Health Gmbh | Neue antiparasitäre Kombination von Wirkstoffen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1567111A1 (de) * | 1965-08-06 | 1970-04-16 | Shell Int Research | Herbizide Mittel |
| US3480643A (en) * | 1967-05-09 | 1969-11-25 | American Cyanamid Co | Alkylsulfonylbenzimidazoles |
-
1970
- 1970-09-09 NL NL7013343A patent/NL7013343A/xx not_active Application Discontinuation
- 1970-09-14 CA CA093,092,A patent/CA950468A/en not_active Expired
- 1970-09-15 IL IL35291A patent/IL35291A0/xx unknown
- 1970-09-21 GB GB44896/70A patent/GB1286603A/en not_active Expired
- 1970-09-21 CH CH1395070A patent/CH556341A/xx not_active IP Right Cessation
- 1970-09-24 FR FR7034620A patent/FR2070090B1/fr not_active Expired
- 1970-09-25 DE DE19702047369 patent/DE2047369A1/de not_active Withdrawn
- 1970-09-25 ZA ZA706553A patent/ZA706553B/xx unknown
- 1970-09-26 JP JP45083805A patent/JPS4932535B1/ja active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0219192A3 (en) * | 1985-08-08 | 1987-06-24 | Schering Agrochemicals Limited | Fungicides |
| US5482956A (en) * | 1992-11-06 | 1996-01-09 | Bayer Aktiengesellschaft | Method of treating parastic protozoa with substituted benzimidazoles |
| AU670317B2 (en) * | 1992-11-06 | 1996-07-11 | Bayer Animal Health Gmbh | Use of substituted benzimidazoles |
| WO2011058139A1 (en) * | 2009-11-12 | 2011-05-19 | Selvita Sp. Z O. O. | A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
| CN102712601A (zh) * | 2009-11-12 | 2012-10-03 | 赛尔维他股份公司 | 化合物、其制备方法、药物组合物、化合物的用途、用于调节或调控丝氨酸/苏氨酸激酶的方法以及丝氨酸/苏氨酸激酶调节剂 |
| US8604217B2 (en) | 2009-11-12 | 2013-12-10 | Selvita S.A. | Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7013343A (enrdf_load_stackoverflow) | 1971-03-30 |
| DE2047369A1 (de) | 1971-04-01 |
| FR2070090A1 (enrdf_load_stackoverflow) | 1971-09-10 |
| IL35291A0 (en) | 1970-11-30 |
| CH556341A (de) | 1974-11-29 |
| JPS4932535B1 (enrdf_load_stackoverflow) | 1974-08-31 |
| FR2070090B1 (enrdf_load_stackoverflow) | 1974-09-20 |
| ZA706553B (en) | 1972-05-31 |
| CA950468A (en) | 1974-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |