GB1281499A - Benzodiazepine derivatives - Google Patents
Benzodiazepine derivativesInfo
- Publication number
- GB1281499A GB1281499A GB26331/71A GB2633171A GB1281499A GB 1281499 A GB1281499 A GB 1281499A GB 26331/71 A GB26331/71 A GB 26331/71A GB 2633171 A GB2633171 A GB 2633171A GB 1281499 A GB1281499 A GB 1281499A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- formula
- alkoxy
- compound
- april
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title abstract 2
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 12
- 150000001875 compounds Chemical class 0.000 abstract 5
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- GXGJIOMUZAGVEH-UHFFFAOYSA-N Chamazulene Chemical group CCC1=CC=C(C)C2=CC=C(C)C2=C1 GXGJIOMUZAGVEH-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 125000005997 bromomethyl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- DTKOQJNQMOCKQU-UHFFFAOYSA-N ethyl 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate Chemical compound C12=CC(Cl)=CC=C2NC(=O)C(C(=O)OCC)N=C1C1=CC=CC=C1 DTKOQJNQMOCKQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US026068A US3905956A (en) | 1969-10-02 | 1970-04-06 | Tricyclic benzodiazepines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1281499A true GB1281499A (en) | 1972-07-12 |
Family
ID=21829705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB26331/71A Expired GB1281499A (en) | 1970-04-06 | 1971-04-19 | Benzodiazepine derivatives |
Country Status (15)
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914215A (en) * | 1967-11-27 | 1975-10-21 | Sankyo Co | Benzodiazepine derivatives and process for preparing the same |
-
1971
- 1971-03-24 CH CH81674A patent/CH574443A5/xx not_active IP Right Cessation
- 1971-03-24 CH CH433471A patent/CH558807A/xx not_active IP Right Cessation
- 1971-03-24 CH CH425671A patent/CH569015A5/xx not_active IP Right Cessation
- 1971-03-24 CH CH81774A patent/CH574960A5/xx not_active IP Right Cessation
- 1971-03-24 CH CH425771A patent/CH547810A/xx not_active IP Right Cessation
- 1971-03-24 CH CH103674A patent/CH579569A5/xx not_active IP Right Cessation
- 1971-03-24 CH CH103774A patent/CH579088A5/xx not_active IP Right Cessation
- 1971-04-01 NL NL7104373.A patent/NL165169C/xx not_active IP Right Cessation
- 1971-04-05 AT AT392172A patent/AT307427B/de not_active IP Right Cessation
- 1971-04-05 ZA ZA712178A patent/ZA712178B/xx unknown
- 1971-04-05 DE DE19712116532 patent/DE2116532A1/de active Pending
- 1971-04-05 BE BE765252A patent/BE765252A/xx unknown
- 1971-04-05 IL IL36551A patent/IL36551A/xx unknown
- 1971-04-05 DE DE19712116499 patent/DE2116499A1/de active Pending
- 1971-04-05 ES ES389911A patent/ES389911A1/es not_active Expired
- 1971-04-05 FR FR7111884A patent/FR2092007B1/fr not_active Expired
- 1971-04-05 BE BE765253A patent/BE765253A/xx unknown
- 1971-04-05 FR FR7111882A patent/FR2092006B1/fr not_active Expired
- 1971-04-05 IL IL36550A patent/IL36550A0/xx unknown
- 1971-04-05 AT AT288071A patent/AT308119B/de not_active IP Right Cessation
- 1971-04-05 ZA ZA712179A patent/ZA712179B/xx unknown
- 1971-04-06 YU YU852/71A patent/YU35026B/xx unknown
- 1971-04-06 NL NL7104585A patent/NL7104585A/xx unknown
- 1971-04-06 HU HUHO1368A patent/HU163551B/hu unknown
- 1971-04-06 CA CA109,679A patent/CA1042886A/en not_active Expired
- 1971-04-06 CA CA109,680A patent/CA946385A/en not_active Expired
- 1971-04-06 NL NL7104592A patent/NL7104592A/xx unknown
- 1971-04-06 JP JP2132371A patent/JPS5320520B1/ja active Pending
- 1971-04-06 CA CA109,681A patent/CA1041499A/en not_active Expired
- 1971-04-06 AR AR234883A patent/AR192875A1/es active
- 1971-04-19 GB GB26331/71A patent/GB1281499A/en not_active Expired
-
1972
- 1972-04-12 AR AR241430A patent/AR200635A1/es active
- 1972-04-12 AR AR241431A patent/AR200636A1/es active
-
1978
- 1978-09-21 YU YU2238/78A patent/YU35005B/xx unknown
- 1978-09-21 YU YU2239/78A patent/YU35006B/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |