GB1276776A - Process for the production of pyridine-carboxylic acids - Google Patents

Process for the production of pyridine-carboxylic acids

Info

Publication number
GB1276776A
GB1276776A GB45147/70A GB4514770A GB1276776A GB 1276776 A GB1276776 A GB 1276776A GB 45147/70 A GB45147/70 A GB 45147/70A GB 4514770 A GB4514770 A GB 4514770A GB 1276776 A GB1276776 A GB 1276776A
Authority
GB
United Kingdom
Prior art keywords
pyridine
flow tube
reaction
temperature
sept
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB45147/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Publication of GB1276776A publication Critical patent/GB1276776A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

1276776 Pyridine carboxylic acids LONZA Ltd 22 Sept 1970 [24 Sept 1969] 45147/70 Heading C2C A pyridine-carboxylic acid is prepared by oxidizing an alkyl-pyridine and/or a heterocyclic compound which carries a pyridine nucleus and which is substituted in at least one position by a group which is oxidizable under the reaction conditions to a carboxylic acid radical, comprising passing at least one said alkyl-pyridine or heterocyclic compound with an excess of nitric acid through an inert flow tube at a temperature of 180-370‹ C. and pressure of 20-500 atmospheres, the reaction temperature being attained and maintained by generating the thermal energy required directly in the wall of the flow tube and discharging the product from the flow tube. An electric current may suitably be passed through the material of the flow tube e.g. by making it the secondary winding of a transformer and the part of the flow tube which forms the reaction path is short-circuited. Advantageously, the pressure and temperature of the reaction product are partially reduced, prior to its discharge from the flow tube, by a baffle system connected before a discharge valve in the flow path. An example describes the preparation of nicotinic acid and the process may be used to prepare picolinic, and cinchomeric acids.
GB45147/70A 1969-09-24 1970-09-22 Process for the production of pyridine-carboxylic acids Expired GB1276776A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1441969A CH515903A (en) 1969-09-24 1969-09-24 Process for the preparation of pyridinecarboxylic acids

Publications (1)

Publication Number Publication Date
GB1276776A true GB1276776A (en) 1972-06-07

Family

ID=4400679

Family Applications (1)

Application Number Title Priority Date Filing Date
GB45147/70A Expired GB1276776A (en) 1969-09-24 1970-09-22 Process for the production of pyridine-carboxylic acids

Country Status (13)

Country Link
JP (1) JPS5335950B1 (en)
AT (1) AT300809B (en)
BE (1) BE756534A (en)
CH (1) CH515903A (en)
DE (1) DE2046556A1 (en)
ES (1) ES383857A1 (en)
FR (1) FR2062985B1 (en)
GB (1) GB1276776A (en)
IT (1) IT1035029B (en)
NL (1) NL7013937A (en)
RO (1) RO59308A (en)
SE (1) SE394814B (en)
ZA (1) ZA706488B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3614019A1 (en) * 1986-04-25 1987-11-05 Degussa METHOD FOR PRODUCING HIGH PURITY CRYSTAL CRYSTALLINE NICOTINIC ACID

Also Published As

Publication number Publication date
DE2046556A1 (en) 1971-04-22
RO59308A (en) 1976-03-15
BE756534A (en) 1971-03-01
ZA706488B (en) 1972-04-26
IT1035029B (en) 1979-10-20
CH515903A (en) 1971-11-30
ES383857A1 (en) 1973-07-16
AT300809B (en) 1972-08-10
NL7013937A (en) 1971-03-26
FR2062985B1 (en) 1973-01-12
FR2062985A1 (en) 1971-07-02
SE394814B (en) 1977-07-11
JPS5335950B1 (en) 1978-09-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee