GB1269908A - Amino acids having anti-viral effects - Google Patents
Amino acids having anti-viral effectsInfo
- Publication number
- GB1269908A GB1269908A GB42828/70A GB4282870A GB1269908A GB 1269908 A GB1269908 A GB 1269908A GB 42828/70 A GB42828/70 A GB 42828/70A GB 4282870 A GB4282870 A GB 4282870A GB 1269908 A GB1269908 A GB 1269908A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- amino acids
- fluorenesulphonyl
- nitrophenylalanine
- sept
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical compound O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- CTPLVEJUYJMNTK-NRFANRHFSA-N (2S)-2-(9H-fluoren-2-ylsulfonylamino)-3-(4-nitrophenyl)propanoic acid Chemical compound C1=C(C=CC=2C3=CC=CC=C3CC12)S(=O)(=O)N[C@@H](CC1=CC=C(C=C1)[N+](=O)[O-])C(=O)O CTPLVEJUYJMNTK-NRFANRHFSA-N 0.000 abstract 1
- WQIPRMQQGQRYCY-KRWDZBQOSA-N (2s)-2-(9h-fluoren-2-ylsulfonylamino)-3-methylbutanoic acid Chemical compound C1=CC=C2C3=CC=C(S(=O)(=O)N[C@@H](C(C)C)C(O)=O)C=C3CC2=C1 WQIPRMQQGQRYCY-KRWDZBQOSA-N 0.000 abstract 1
- FLPMPWDSYOPNEJ-ZDUSSCGKSA-N (2s)-2-(furan-2-ylmethylamino)-3-phenylpropanoic acid Chemical compound C([C@@H](C(=O)O)NCC=1OC=CC=1)C1=CC=CC=C1 FLPMPWDSYOPNEJ-ZDUSSCGKSA-N 0.000 abstract 1
- OILCBBLXRDNCQW-HNNXBMFYSA-N (2s)-2-[[2-(4-nitrophenoxy)acetyl]amino]-3-(4-nitrophenyl)propanoic acid Chemical compound C([C@@H](C(=O)O)NC(=O)COC=1C=CC(=CC=1)[N+]([O-])=O)C1=CC=C([N+]([O-])=O)C=C1 OILCBBLXRDNCQW-HNNXBMFYSA-N 0.000 abstract 1
- FLUYDOVOMDZUEV-UHFFFAOYSA-N 2-(4-nitrophenoxy)acetyl chloride Chemical compound [O-][N+](=O)C1=CC=C(OCC(Cl)=O)C=C1 FLUYDOVOMDZUEV-UHFFFAOYSA-N 0.000 abstract 1
- AVDLFIONKHGQAP-UHFFFAOYSA-N 4-nitrophenoxyacetic acid Chemical compound OC(=O)COC1=CC=C([N+]([O-])=O)C=C1 AVDLFIONKHGQAP-UHFFFAOYSA-N 0.000 abstract 1
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000003862 amino acid derivatives Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1288020D GB1288020A (https=) | 1969-09-06 | 1970-09-07 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7071669 | 1969-09-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1269908A true GB1269908A (en) | 1972-04-06 |
Family
ID=13439555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB42828/70A Expired GB1269908A (en) | 1969-09-06 | 1970-09-07 | Amino acids having anti-viral effects |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3801633A (https=) |
| DE (1) | DE2043933C3 (https=) |
| FR (1) | FR2070675B1 (https=) |
| GB (1) | GB1269908A (https=) |
| NL (1) | NL7013043A (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU735013B2 (en) * | 1996-09-04 | 2001-06-28 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
| MD4110C1 (ro) * | 2010-10-21 | 2011-12-31 | Валериу РУДИК | Preparat antiherpetiс |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4165258A (en) * | 1975-10-08 | 1979-08-21 | University Of Pennsylvania | Plasminogen activating enzyme-specific competitive inhibitor |
| US4070478A (en) * | 1977-02-17 | 1978-01-24 | Merck & Co., Inc. | Benzimidazole substituted alanines |
| FR2508444A1 (fr) * | 1981-06-29 | 1982-12-31 | Irceba | Nouveaux derives sulfonyle du tryptophane utiles en tant que medicaments et leur procede de preparation |
| US5079260A (en) * | 1989-06-22 | 1992-01-07 | Nova Pharmaceutical Corporation | Method for treating inflammation and compounds and compositions suitable for use therein |
| US5472973A (en) * | 1991-12-12 | 1995-12-05 | Scios Nova Inc. | Fluorenyl derivatives as anti-inflammatory agents |
| WO1993011764A1 (en) * | 1991-12-12 | 1993-06-24 | Scios Nova Inc. | Fluorenyl derivatives and their use as anti-inflammatory agents |
| WO2013148991A1 (en) | 2012-03-30 | 2013-10-03 | Givaudan S.A. | N-acyl derivatives of gamma amino - butyric acid and and beta alanine as food flavouring compounds |
| EP2830438B1 (en) | 2012-03-30 | 2019-09-04 | Givaudan SA | N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds, powder compositions containing them |
| US10913922B2 (en) | 2012-03-30 | 2021-02-09 | Givaudan S.A. | N-acylated methionine derivatives as food flavoring compounds |
| BR112014023959B1 (pt) | 2012-03-30 | 2020-10-20 | Givaudan Sa | composição comestível |
| SG11201405104PA (en) | 2012-03-30 | 2014-10-30 | Givaudan Sa | Improvements in or relating to organic compounds |
| EP2830437B1 (en) | 2012-03-30 | 2018-12-26 | Givaudan SA | N-acylated 1-aminocycloalkyl carboxylic acids as food flavouring compounds |
| CN104219964B (zh) | 2012-03-30 | 2016-09-21 | 奇华顿股份有限公司 | 作为食品加香化合物的n-酰基脯氨酸衍生物 |
| WO2015050536A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | N-acylated 2-aminoisobutyric acid compounds and flavour compositions containing them |
| US10674755B2 (en) | 2013-10-02 | 2020-06-09 | Givaudan S.A. | Organic Compounds |
| WO2015050537A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
| EP3057444B1 (en) | 2013-10-02 | 2017-12-06 | Givaudan SA | Organic compounds having taste-modifying properties |
| GB201317424D0 (en) | 2013-10-02 | 2013-11-13 | Givaudan Sa | Improvements in or relating to organic compounds |
| EP3057445B1 (en) | 2013-10-02 | 2018-07-04 | Givaudan SA | Organic compounds having taste-modifying properties |
| WO2015050538A1 (en) * | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
| WO2015050535A1 (en) | 2013-10-02 | 2015-04-09 | Givaudan S.A. | Organic compounds |
-
1970
- 1970-09-03 NL NL7013043A patent/NL7013043A/xx not_active Application Discontinuation
- 1970-09-04 DE DE2043933A patent/DE2043933C3/de not_active Expired
- 1970-09-04 US US00069993A patent/US3801633A/en not_active Expired - Lifetime
- 1970-09-07 FR FR7032462A patent/FR2070675B1/fr not_active Expired
- 1970-09-07 GB GB42828/70A patent/GB1269908A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU735013B2 (en) * | 1996-09-04 | 2001-06-28 | Warner-Lambert Company | Matrix metalloproteinase inhibitors and their therapeutic uses |
| MD4110C1 (ro) * | 2010-10-21 | 2011-12-31 | Валериу РУДИК | Preparat antiherpetiс |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2043933C3 (de) | 1978-05-18 |
| FR2070675A1 (https=) | 1971-09-17 |
| DE2043933A1 (de) | 1971-03-11 |
| DE2043933B2 (de) | 1977-09-08 |
| NL7013043A (https=) | 1971-03-09 |
| FR2070675B1 (https=) | 1974-09-27 |
| US3801633A (en) | 1974-04-02 |
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