GB1260907A - Indole derivatives - Google Patents
Indole derivativesInfo
- Publication number
- GB1260907A GB1260907A GB2658169A GB2658169A GB1260907A GB 1260907 A GB1260907 A GB 1260907A GB 2658169 A GB2658169 A GB 2658169A GB 2658169 A GB2658169 A GB 2658169A GB 1260907 A GB1260907 A GB 1260907A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reacting
- methylindole
- hydroxy
- benzyl
- epibromohydrin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title abstract 2
- 150000002475 indoles Chemical class 0.000 title abstract 2
- XBVSGEGNQZAQPM-UHFFFAOYSA-N 2-methyl-1h-indol-4-ol Chemical compound C1=CC=C2NC(C)=CC2=C1O XBVSGEGNQZAQPM-UHFFFAOYSA-N 0.000 abstract 2
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- GKIPXFAANLTWBM-UHFFFAOYSA-N epibromohydrin Chemical compound BrCC1CO1 GKIPXFAANLTWBM-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NHEJGHMDYRCACH-UHFFFAOYSA-N 1-[(2-methyl-1H-indol-4-yl)oxy]-3-(propan-2-ylideneamino)propan-2-ol Chemical compound OC(COC1=C2C=C(NC2=CC=C1)C)CN=C(C)C NHEJGHMDYRCACH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000674 adrenergic antagonist Substances 0.000 abstract 1
- -1 benzyl tert.-butylamine Chemical compound 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- JJWLVOIRVHMVIS-UHFFFAOYSA-N isopropylamine Chemical compound CC(C)N JJWLVOIRVHMVIS-UHFFFAOYSA-N 0.000 abstract 1
- LYBKPDDZTNUNNM-UHFFFAOYSA-N isopropylbenzylamine Chemical compound CC(C)NCC1=CC=CC=C1 LYBKPDDZTNUNNM-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR17682968 | 1968-06-07 | ||
| DE19681620342 DE1620342A1 (de) | 1965-02-01 | 1968-09-04 | Verfahren zur Herstellung neuer Indolderivate |
| CH1838768A CH502337A (de) | 1965-02-01 | 1968-12-10 | Verfahren zur Herstellung neuer Indolderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1260907A true GB1260907A (en) | 1972-01-19 |
Family
ID=27160205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2658169A Expired GB1260907A (en) | 1968-06-07 | 1969-05-23 | Indole derivatives |
Country Status (2)
| Country | Link |
|---|---|
| CS (1) | CS159759B2 (enrdf_load_stackoverflow) |
| GB (1) | GB1260907A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2173399A (en) * | 1985-02-05 | 1986-10-15 | Sandoz Ltd | Compositions containing 3-aminopropoxy-indoles for treating hypertension |
-
1969
- 1969-05-23 GB GB2658169A patent/GB1260907A/en not_active Expired
- 1969-06-05 CS CS399869A patent/CS159759B2/cs unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2173399A (en) * | 1985-02-05 | 1986-10-15 | Sandoz Ltd | Compositions containing 3-aminopropoxy-indoles for treating hypertension |
| AT393960B (de) * | 1985-02-05 | 1992-01-10 | Sandoz Ag | Verfahren zur kombination eines beta-adrenorezeptorblockers und eines diuretikums |
Also Published As
| Publication number | Publication date |
|---|---|
| CS159759B2 (enrdf_load_stackoverflow) | 1975-01-31 |
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