GB1258691A - - Google Patents
Info
- Publication number
- GB1258691A GB1258691A GB1258691DA GB1258691A GB 1258691 A GB1258691 A GB 1258691A GB 1258691D A GB1258691D A GB 1258691DA GB 1258691 A GB1258691 A GB 1258691A
- Authority
- GB
- United Kingdom
- Prior art keywords
- digoxin
- diacetate
- acetates
- april
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 abstract 3
- 229960005156 digoxin Drugs 0.000 abstract 3
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 abstract 3
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 abstract 3
- 229940097217 cardiac glycoside Drugs 0.000 abstract 2
- 239000002368 cardiac glycoside Substances 0.000 abstract 2
- LPMXVESGRSUGHW-HBYQJFLCSA-N ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 abstract 2
- 229930002534 steroid glycoside Natural products 0.000 abstract 2
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691921633 DE1921633C3 (de) | 1969-04-28 | I5',16'-Diacetylierte Derivate von Digoxin, Digitoxin und Gitoxin sowie Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1258691A true GB1258691A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-12-30 |
Family
ID=5732661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1258691D Expired GB1258691A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-04-28 | 1970-04-28 |
Country Status (6)
-
1970
- 1970-04-28 DK DK214770A patent/DK123525B/da unknown
- 1970-04-28 CH CH635570A patent/CH527810A/de not_active IP Right Cessation
- 1970-04-28 NL NL7006186A patent/NL7006186A/xx unknown
- 1970-04-28 GB GB1258691D patent/GB1258691A/en not_active Expired
- 1970-04-28 BE BE749680D patent/BE749680A/xx unknown
- 1970-04-28 AT AT385970A patent/AT300204B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT300204B (de) | 1972-07-25 |
| DE1921633A1 (de) | 1970-11-12 |
| DK123525B (da) | 1972-07-03 |
| BE749680A (fr) | 1970-10-01 |
| CH527810A (de) | 1972-09-15 |
| DE1921633B2 (de) | 1977-06-16 |
| NL7006186A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |