GB1256007A - Chromatographic method for the resolution of optical isomers - Google Patents

Chromatographic method for the resolution of optical isomers

Info

Publication number
GB1256007A
GB1256007A GB33135/69A GB3313569A GB1256007A GB 1256007 A GB1256007 A GB 1256007A GB 33135/69 A GB33135/69 A GB 33135/69A GB 3313569 A GB3313569 A GB 3313569A GB 1256007 A GB1256007 A GB 1256007A
Authority
GB
United Kingdom
Prior art keywords
sorbent
complex
metal ion
mixtures
stereoisomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB33135/69A
Inventor
Sergei Vasilievich Rogozhin
Vadim Alexandrovich Davankov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I ELEMENTOORGANICHESKIKH SOEDI
Original Assignee
I ELEMENTOORGANICHESKIKH SOEDI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I ELEMENTOORGANICHESKIKH SOEDI filed Critical I ELEMENTOORGANICHESKIKH SOEDI
Publication of GB1256007A publication Critical patent/GB1256007A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J45/00—Ion-exchange in which a complex or a chelate is formed; Use of material as complex or chelate forming ion-exchangers; Treatment of material for improving the complex or chelate forming ion-exchange properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00—Ion-exchange processes in general; Apparatus therefor
    • B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,256,007. Chromatographic separation of stereoisomers. ORDENA LENINA INSTITUT ELEMENTOORGANICHESKIKH SOEDINENY AKADEMII NAUK SSSR. 1 July, 1969 [1 July, 1968], No. 33135/69. Heading B1X. [Also in Division C3] Mixtures of stereoisomers, e.g. racemic mixtures, which form a complex with a transition metal ion are chromatographically separated using an optically active asymmetric sorbent in the form of a complex with the same transition metal ion. The sorbent is preferably the product obtained by treating a cross-linked chloromethylated styrene copolymer with an optically active α- or #-aminocarboxylic or -aminophosphonic acid or an amide or ester thereof and then introducing a copper or nickel ion (see Division C3), but may also be the product obtained by reacting formaldehyde with tyrosine or a derivative thereof, or be a derivative of chitosan or alginic acid. The process is particularly applicable to the separation of amino acid mixtures using water and/or ammonia as eluent, and is preferably carried out by passing the eluate containing the eluted material in the form of a metal complex through a further column of the same sorbent which is not in the form of a metal complex, whereby the metal ion is removed from the separated material. Alternatively, the sorbent in complex form may comprise the centre portion of a single bed, the upper and lower portions consisting of uncomplexed sorbent, successive runs being performed in opposite directions to ensure that the metal ion is not removed from the column and remains generally in the centre of the bed.
GB33135/69A 1968-07-01 1969-07-01 Chromatographic method for the resolution of optical isomers Expired GB1256007A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU1248975 1968-07-01

Publications (1)

Publication Number Publication Date
GB1256007A true GB1256007A (en) 1971-12-08

Family

ID=20442721

Family Applications (1)

Application Number Title Priority Date Filing Date
GB33135/69A Expired GB1256007A (en) 1968-07-01 1969-07-01 Chromatographic method for the resolution of optical isomers

Country Status (3)

Country Link
DE (1) DE1932190A1 (en)
FR (1) FR2012102A1 (en)
GB (1) GB1256007A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2536586B2 (en) * 1988-04-08 1996-09-18 住友化学工業株式会社 Amino acid separation and purification method
EP0496513A3 (en) * 1991-01-14 1993-12-29 Babcock Hitachi Kk Process for producing ionexchange resins and use of the resins for separating amino acids

Also Published As

Publication number Publication date
FR2012102A1 (en) 1970-03-13
DE1932190A1 (en) 1970-01-08

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