GB1254417A - Diagnostic agents - Google Patents

Diagnostic agents

Info

Publication number
GB1254417A
GB1254417A GB1646670A GB1646670A GB1254417A GB 1254417 A GB1254417 A GB 1254417A GB 1646670 A GB1646670 A GB 1646670A GB 1646670 A GB1646670 A GB 1646670A GB 1254417 A GB1254417 A GB 1254417A
Authority
GB
United Kingdom
Prior art keywords
atom
hydroperoxides
chromogen
lower alkyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1646670A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691917996 external-priority patent/DE1917996C3/en
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of GB1254417A publication Critical patent/GB1254417A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B26/00Hydrazone dyes; Triazene dyes
    • C09B26/02Hydrazone dyes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00Chromogens for determinations of oxidoreductase enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

1,254,417. Determination of hydrogen peroxide, peroxidase &c. BOEHRINGER MANNHEIM G.m.b.H. 7 April, 1970 [7 April, 1969], No. 16466/70. Addition to 1,186,668. Heading B1X. In the determination of hydroperoxides, of substances which react with the liberation of hydroperoxides, of peroxidase or of peroxidate active substances using the reaction of the hydroperoxides with a chromogen, which reaction is catalysed by peroxidase or peroxidate active substances, the chromogen used has the general formula: in which R 1 is a lower alkyl radical, R 2 is a hydrogen atom, a sulphonic acid group or an alkali metal or ammonium sulphonate group, R3<SP>1</SP> is a hydrogen atom, a halogen atom or a lower alkyl radical, Y is a nitrogen atom or a methine group which together with R 3 <SP>1</SP> can form a benzene ring substituted by R 2 , one of the substituents X<SP>1</SP> is a sulphur atom, a vinyradical, an imino group, which can be substituted by a lower alkyl or an aryl radical, an oxygen atom or a carbon atom substituted by two lower alkyl radicals, while the other substituent X<SP>1</SP> is an oxygen atom or a carbon atom substituted by two lower alkyl radicals. The chromogen may be mixed with a modifier of general formula: in which Ar is a benzene or naphthalene nucleus V is hydroxyl or amino, V<SP>1</SP> is hydrogen or hydroxyl or amino, which may be alkylated or arylated, W is an amino, carboxyl, or sulphonic acid group or an alkyl, alkoxy, or aryl radical, W<SP>1</SP> is hydrogen or an amino group or a carboxyl or sulphonic acid group in free form or as an ammonium or alkali metal salt, or an alkyl, alkoxy or aryl radical. Diagnostic agents comprise peroxidase or a peroxidate active substance and a chromogen (for determination of hydroperoxides or substances reacting to give hydroperoxides); hydrogen peroxide or a substance forming hydrogen peroxide and a chromogen (for determination of haemoglobin or of other peroxidate active substances). The agents may be in the form of solutions or test papers or in films on foil.
GB1646670A 1969-04-09 1970-04-07 Diagnostic agents Expired GB1254417A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691917996 DE1917996C3 (en) 1969-04-09 Procedures and diagnostic tools. for the determination of hydroperoxides and peroxidatically active substances

Publications (1)

Publication Number Publication Date
GB1254417A true GB1254417A (en) 1971-11-24

Family

ID=5730676

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1646670A Expired GB1254417A (en) 1969-04-09 1970-04-07 Diagnostic agents

Country Status (6)

Country Link
AT (1) AT297665B (en)
CA (1) CA919563A (en)
FI (1) FI50911C (en)
FR (1) FR2043072A6 (en)
GB (1) GB1254417A (en)
NL (1) NL165300C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0105747A1 (en) * 1982-10-06 1984-04-18 Venturecare Limited Hygiene-testing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0105747A1 (en) * 1982-10-06 1984-04-18 Venturecare Limited Hygiene-testing

Also Published As

Publication number Publication date
NL165300B (en) 1980-10-15
FI50911B (en) 1976-04-30
AT297665B (en) 1972-04-10
NL165300C (en) 1981-03-16
NL7005081A (en) 1970-10-13
FI50911C (en) 1976-08-10
CA919563A (en) 1973-01-23
FR2043072A6 (en) 1971-02-12

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