GB1246606A - Dibenzo-azepine derivatives - Google Patents
Dibenzo-azepine derivativesInfo
- Publication number
- GB1246606A GB1246606A GB1836270A GB1836270A GB1246606A GB 1246606 A GB1246606 A GB 1246606A GB 1836270 A GB1836270 A GB 1836270A GB 1836270 A GB1836270 A GB 1836270A GB 1246606 A GB1246606 A GB 1246606A
- Authority
- GB
- United Kingdom
- Prior art keywords
- iminodibenzyl
- chlorocarbonyl
- dehydrobromination
- dibenzo
- azepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007655 dibenzoazepines Chemical class 0.000 title 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- 238000007269 dehydrobromination reaction Methods 0.000 abstract 3
- -1 5 - chlorocarbonyl - iminodibenzyl Chemical group 0.000 abstract 2
- 230000009435 amidation Effects 0.000 abstract 2
- 238000007112 amidation reaction Methods 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- LCGTWRLJTMHIQZ-UHFFFAOYSA-N 5H-dibenzo[b,f]azepine Chemical class C1=CC2=CC=CC=C2NC2=CC=CC=C21 LCGTWRLJTMHIQZ-UHFFFAOYSA-N 0.000 abstract 1
- ZSMRRZONCYIFNB-UHFFFAOYSA-N 6,11-dihydro-5h-benzo[b][1]benzazepine Chemical group C1CC2=CC=CC=C2NC2=CC=CC=C12 ZSMRRZONCYIFNB-UHFFFAOYSA-N 0.000 abstract 1
- 229920002292 Nylon 6 Polymers 0.000 abstract 1
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- FFGPTBGBLSHEPO-UHFFFAOYSA-N carbamazepine Chemical compound C1=CC2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 FFGPTBGBLSHEPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- VRLDVERQJMEPIF-UHFFFAOYSA-N dbdmh Chemical compound CC1(C)N(Br)C(=O)N(Br)C1=O VRLDVERQJMEPIF-UHFFFAOYSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL133242A PL64802B1 (enrdf_load_stackoverflow) | 1969-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1246606A true GB1246606A (en) | 1971-09-15 |
Family
ID=19950545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1836270A Expired GB1246606A (en) | 1969-04-28 | 1970-04-17 | Dibenzo-azepine derivatives |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS5022035B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1246606A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4307181C1 (de) * | 1993-03-08 | 1994-11-10 | Dresden Arzneimittel | Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid |
| DE4421294A1 (de) * | 1994-06-17 | 1995-12-21 | Chemie Linz Deutschland | Verfahren zur Herstellung von 5H-Dibenz-(b,f)-azepin-5-carboxamid |
| US7208501B2 (en) | 2000-12-22 | 2007-04-24 | Almirall Prodesfarma Ag | Quinuclidine carbamate derivatives and their use as M3 antagonists |
| WO2007025709A3 (en) * | 2005-08-31 | 2007-05-10 | Novartis Ag | Organic compounds |
| US7435742B2 (en) | 2002-06-21 | 2008-10-14 | Laboratorios Almirall S.A. | Quinuclidine derivatives and pharmaceutical compositions containing the same |
| US7718670B2 (en) | 2002-07-02 | 2010-05-18 | Laboratorios Almirall S.A | Quinuclidine amide derivatives |
| WO2020157257A1 (en) | 2019-02-01 | 2020-08-06 | H. Lundbeck A/S | Injectable carbamazepine composition essentially free of 10-br-carbamazepine |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5320042U (enrdf_load_stackoverflow) * | 1976-07-29 | 1978-02-20 | ||
| JPS5420150U (enrdf_load_stackoverflow) * | 1977-07-13 | 1979-02-08 |
-
1970
- 1970-04-17 GB GB1836270A patent/GB1246606A/en not_active Expired
- 1970-04-24 JP JP3482270A patent/JPS5022035B1/ja active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4307181C1 (de) * | 1993-03-08 | 1994-11-10 | Dresden Arzneimittel | Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid |
| DE4421294A1 (de) * | 1994-06-17 | 1995-12-21 | Chemie Linz Deutschland | Verfahren zur Herstellung von 5H-Dibenz-(b,f)-azepin-5-carboxamid |
| US7208501B2 (en) | 2000-12-22 | 2007-04-24 | Almirall Prodesfarma Ag | Quinuclidine carbamate derivatives and their use as M3 antagonists |
| US7312231B2 (en) | 2000-12-22 | 2007-12-25 | Almirall Prodesfarma Ag | Quinuclidine carbamate derivatives and their use as M3 antagonists |
| US7776879B2 (en) | 2000-12-22 | 2010-08-17 | Almirall, S.A. | Quinuclidine carbamate derivatives and their use as M3 antagonists |
| US7435742B2 (en) | 2002-06-21 | 2008-10-14 | Laboratorios Almirall S.A. | Quinuclidine derivatives and pharmaceutical compositions containing the same |
| US7718670B2 (en) | 2002-07-02 | 2010-05-18 | Laboratorios Almirall S.A | Quinuclidine amide derivatives |
| WO2007025709A3 (en) * | 2005-08-31 | 2007-05-10 | Novartis Ag | Organic compounds |
| EP2096104A1 (en) * | 2005-08-31 | 2009-09-02 | Novartis AG | Organic diamines as mGluR7 modulators |
| WO2020157257A1 (en) | 2019-02-01 | 2020-08-06 | H. Lundbeck A/S | Injectable carbamazepine composition essentially free of 10-br-carbamazepine |
| US11529357B2 (en) | 2019-02-01 | 2022-12-20 | H. Lundbeck A/S | Injectable carbamazepine composition essentially free of 10-bromo-carbamazepine |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5022035B1 (enrdf_load_stackoverflow) | 1975-07-28 |
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