GB1235684A - Improvements in or relating to nitrogen-containing heterocyclic derivatives - Google Patents
Improvements in or relating to nitrogen-containing heterocyclic derivativesInfo
- Publication number
- GB1235684A GB1235684A GB52985/67A GB5298567A GB1235684A GB 1235684 A GB1235684 A GB 1235684A GB 52985/67 A GB52985/67 A GB 52985/67A GB 5298567 A GB5298567 A GB 5298567A GB 1235684 A GB1235684 A GB 1235684A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkoxy
- substituted
- optionally
- phenylalkylthio
- phenylalkylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
1,235,684. Basic alcohols, ethers and esters. CENTRE DE RECHERCHES MARCEL MIDY. 15 Nov., 1968 [21 Nov., 1967], No. 52985/67. Heading C2C. Compounds of the general formula (Z=CH 2 CH 2 , CH=CH, CH 2 CH 2 CH 2 , CH 2 CH= CH; R=H, saturated or unsaturated C 1-8 aliphatic group, R 2 CO; R 2 =saturated or unsaturated C 1-6 aliphatic group, or Ph, phenylalkyl, PhOCH 2 , PhSCH 2 optionally ring- substituted by 1-3 substituents selected from Me, alkoxy, halogen; R 1 =Ph, PhO, phenylalkoxy, PhS, phenylalkylthio, PhNH, phenylalkylamino optionally ring - substituted by 1 or 2 substituents selected from NO 2 , NH 2 , halogen, alkyl, alkoxy and C 5-6 cycloalkyl, 2 - naphthyl, 1,2,3,4 - tetrahydro - 6 - naphthyl, C 5-6 cycloalkyl, alkoxy, alkylthio; n=0-2; provided that R 1 =PhO, phenylalkoxy, PhS, phenylalkylthio, PhNH, phenylalkylamino, optionally substituted, only when Z=CH 2 CH 2 or CH=CH) and their acid addition salts are prepared by the following reactions: optionally followed by etherification or esterification and/or salt formation. The preparation of the heterocyclic starting materials by standard methods is described. The above compounds have sympathicolytic, myolytic, psychotropically tranquillizing and analgesic and local anaesthetic activity and may be administered in the form of pharmaceutical preparations contaning them in association with a carrier.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB52985/67A GB1235684A (en) | 1967-11-21 | 1967-11-21 | Improvements in or relating to nitrogen-containing heterocyclic derivatives |
FR1594756D FR1594756A (en) | 1967-11-21 | 1968-11-08 | |
DE19681809286 DE1809286B2 (en) | 1967-11-21 | 1968-11-16 | Tetramethyl-PyiTolidine |
LU57339D LU57339A1 (en) | 1967-11-21 | 1968-11-18 | |
BE724007D BE724007A (en) | 1967-11-21 | 1968-11-18 | |
SE1577368A SE366546B (en) | 1967-11-21 | 1968-11-20 | |
CH1729668A CH523881A (en) | 1967-11-21 | 1968-11-20 | Process for the preparation of new heterocyclic derivatives |
ES360460A ES360460A1 (en) | 1967-11-21 | 1968-11-20 | Improvements in or relating to nitrogen-containing heterocyclic derivatives |
BR20414368A BR6804143D0 (en) | 1967-11-21 | 1968-11-20 | PROCESS FOR THE PREPARATION OF NEW HETEROCYCLICAL COMPOUNDS |
IN118661A IN118661B (en) | 1967-11-21 | 1968-11-20 | |
NL6816639A NL6816639A (en) | 1967-11-21 | 1968-11-21 | |
SU1284072A SU363246A3 (en) | 1967-11-21 | 1968-11-21 | |
CS794668A CS153023B2 (en) | 1967-11-21 | 1968-11-21 | |
AT1132668A AT283340B (en) | 1967-11-21 | 1968-11-21 | Process for the preparation of new heterocyclic compounds and their salts |
IE141268A IE32778B1 (en) | 1967-11-21 | 1968-11-21 | Improvements in or relating to nitrogen-containing heterocyclic derivatives |
FR183247A FR8276M (en) | 1967-11-21 | 1969-02-10 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB52985/67A GB1235684A (en) | 1967-11-21 | 1967-11-21 | Improvements in or relating to nitrogen-containing heterocyclic derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1235684A true GB1235684A (en) | 1971-06-16 |
Family
ID=10466156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB52985/67A Expired GB1235684A (en) | 1967-11-21 | 1967-11-21 | Improvements in or relating to nitrogen-containing heterocyclic derivatives |
Country Status (15)
Country | Link |
---|---|
AT (1) | AT283340B (en) |
BE (1) | BE724007A (en) |
BR (1) | BR6804143D0 (en) |
CH (1) | CH523881A (en) |
CS (1) | CS153023B2 (en) |
DE (1) | DE1809286B2 (en) |
ES (1) | ES360460A1 (en) |
FR (2) | FR1594756A (en) |
GB (1) | GB1235684A (en) |
IE (1) | IE32778B1 (en) |
IN (1) | IN118661B (en) |
LU (1) | LU57339A1 (en) |
NL (1) | NL6816639A (en) |
SE (1) | SE366546B (en) |
SU (1) | SU363246A3 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5823399B2 (en) * | 1973-08-23 | 1983-05-14 | ウェルファイド株式会社 | Phenoxy Amino Probanol |
JPS57136567A (en) * | 1981-02-17 | 1982-08-23 | Adeka Argus Chem Co Ltd | N-2-hydroxy-3-substituted piperidine compound |
-
1967
- 1967-11-21 GB GB52985/67A patent/GB1235684A/en not_active Expired
-
1968
- 1968-11-08 FR FR1594756D patent/FR1594756A/fr not_active Expired
- 1968-11-16 DE DE19681809286 patent/DE1809286B2/en active Granted
- 1968-11-18 BE BE724007D patent/BE724007A/xx unknown
- 1968-11-18 LU LU57339D patent/LU57339A1/xx unknown
- 1968-11-20 IN IN118661A patent/IN118661B/en unknown
- 1968-11-20 CH CH1729668A patent/CH523881A/en not_active IP Right Cessation
- 1968-11-20 BR BR20414368A patent/BR6804143D0/en unknown
- 1968-11-20 SE SE1577368A patent/SE366546B/xx unknown
- 1968-11-20 ES ES360460A patent/ES360460A1/en not_active Expired
- 1968-11-21 CS CS794668A patent/CS153023B2/cs unknown
- 1968-11-21 AT AT1132668A patent/AT283340B/en not_active IP Right Cessation
- 1968-11-21 IE IE141268A patent/IE32778B1/en unknown
- 1968-11-21 SU SU1284072A patent/SU363246A3/ru active
- 1968-11-21 NL NL6816639A patent/NL6816639A/xx unknown
-
1969
- 1969-02-10 FR FR183247A patent/FR8276M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR1594756A (en) | 1970-06-08 |
IE32778B1 (en) | 1973-11-28 |
ES360460A1 (en) | 1970-07-01 |
DE1809286A1 (en) | 1969-08-14 |
BR6804143D0 (en) | 1973-01-09 |
DE1809286C3 (en) | 1975-04-03 |
DE1809286B2 (en) | 1974-08-01 |
AT283340B (en) | 1970-08-10 |
SE366546B (en) | 1974-04-29 |
LU57339A1 (en) | 1969-02-26 |
IN118661B (en) | 1975-08-16 |
CS153023B2 (en) | 1974-02-22 |
FR8276M (en) | 1970-11-02 |
BE724007A (en) | 1969-05-02 |
SU363246A3 (en) | 1972-12-30 |
IE32778L (en) | 1969-05-21 |
NL6816639A (en) | 1969-05-23 |
CH523881A (en) | 1972-06-15 |
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