IE32778L - Nitrogen-containing heterocyclic derivatives - Google Patents

Nitrogen-containing heterocyclic derivatives

Info

Publication number
IE32778L
IE32778L IE141268A IE141268A IE32778L IE 32778 L IE32778 L IE 32778L IE 141268 A IE141268 A IE 141268A IE 141268 A IE141268 A IE 141268A IE 32778 L IE32778 L IE 32778L
Authority
IE
Ireland
Prior art keywords
alkoxy
substituted
optionally
phenylalkylthio
phenylalkylamino
Prior art date
Application number
IE141268A
Other versions
IE32778B1 (en
Original Assignee
Marcel Midy Centre Rech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marcel Midy Centre Rech filed Critical Marcel Midy Centre Rech
Publication of IE32778L publication Critical patent/IE32778L/en
Publication of IE32778B1 publication Critical patent/IE32778B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

1,235,684. Basic alcohols, ethers and esters. CENTRE DE RECHERCHES MARCEL MIDY. 15 Nov., 1968 [21 Nov., 1967], No. 52985/67. Heading C2C. Compounds of the general formula (Z=CH 2 CH 2 , CH=CH, CH 2 CH 2 CH 2 , CH 2 CH= CH; R=H, saturated or unsaturated C 1-8 aliphatic group, R 2 CO; R 2 =saturated or unsaturated C 1-6 aliphatic group, or Ph, phenylalkyl, PhOCH 2 , PhSCH 2 optionally ring- substituted by 1-3 substituents selected from Me, alkoxy, halogen; R 1 =Ph, PhO, phenylalkoxy, PhS, phenylalkylthio, PhNH, phenylalkylamino optionally ring - substituted by 1 or 2 substituents selected from NO 2 , NH 2 , halogen, alkyl, alkoxy and C 5-6 cycloalkyl, 2 - naphthyl, 1,2,3,4 - tetrahydro - 6 - naphthyl, C 5-6 cycloalkyl, alkoxy, alkylthio; n=0-2; provided that R 1 =PhO, phenylalkoxy, PhS, phenylalkylthio, PhNH, phenylalkylamino, optionally substituted, only when Z=CH 2 CH 2 or CH=CH) and their acid addition salts are prepared by the following reactions: optionally followed by etherification or esterification and/or salt formation. The preparation of the heterocyclic starting materials by standard methods is described. The above compounds have sympathicolytic, myolytic, psychotropically tranquillizing and analgesic and local anaesthetic activity and may be administered in the form of pharmaceutical preparations contaning them in association with a carrier. [GB1235684A]
IE141268A 1967-11-21 1968-11-21 Improvements in or relating to nitrogen-containing heterocyclic derivatives IE32778B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB52985/67A GB1235684A (en) 1967-11-21 1967-11-21 Improvements in or relating to nitrogen-containing heterocyclic derivatives

Publications (2)

Publication Number Publication Date
IE32778L true IE32778L (en) 1969-05-21
IE32778B1 IE32778B1 (en) 1973-11-28

Family

ID=10466156

Family Applications (1)

Application Number Title Priority Date Filing Date
IE141268A IE32778B1 (en) 1967-11-21 1968-11-21 Improvements in or relating to nitrogen-containing heterocyclic derivatives

Country Status (15)

Country Link
AT (1) AT283340B (en)
BE (1) BE724007A (en)
BR (1) BR6804143D0 (en)
CH (1) CH523881A (en)
CS (1) CS153023B2 (en)
DE (1) DE1809286B2 (en)
ES (1) ES360460A1 (en)
FR (2) FR1594756A (en)
GB (1) GB1235684A (en)
IE (1) IE32778B1 (en)
IN (1) IN118661B (en)
LU (1) LU57339A1 (en)
NL (1) NL6816639A (en)
SE (1) SE366546B (en)
SU (1) SU363246A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5823399B2 (en) * 1973-08-23 1983-05-14 ウェルファイド株式会社 Phenoxy Amino Probanol
JPS57136567A (en) * 1981-02-17 1982-08-23 Adeka Argus Chem Co Ltd N-2-hydroxy-3-substituted piperidine compound

Also Published As

Publication number Publication date
SU363246A3 (en) 1972-12-30
DE1809286B2 (en) 1974-08-01
IE32778B1 (en) 1973-11-28
DE1809286A1 (en) 1969-08-14
CH523881A (en) 1972-06-15
FR1594756A (en) 1970-06-08
BE724007A (en) 1969-05-02
LU57339A1 (en) 1969-02-26
NL6816639A (en) 1969-05-23
AT283340B (en) 1970-08-10
DE1809286C3 (en) 1975-04-03
GB1235684A (en) 1971-06-16
ES360460A1 (en) 1970-07-01
BR6804143D0 (en) 1973-01-09
CS153023B2 (en) 1974-02-22
FR8276M (en) 1970-11-02
IN118661B (en) 1975-08-16
SE366546B (en) 1974-04-29

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