GB1212138A - Enzyme stabilization - Google Patents

Enzyme stabilization

Info

Publication number
GB1212138A
GB1212138A GB216969A GB216969A GB1212138A GB 1212138 A GB1212138 A GB 1212138A GB 216969 A GB216969 A GB 216969A GB 216969 A GB216969 A GB 216969A GB 1212138 A GB1212138 A GB 1212138A
Authority
GB
United Kingdom
Prior art keywords
enzyme stabilization
asparaginase
solutions
injectable
stabilised
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB216969A
Inventor
Otto Wagner
Klaus Bauer
Wilfried Kaufmann
Erich Rauenbusch
Alfred Arens
Eckart Irion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681767617 external-priority patent/DE1767617A1/en
Priority claimed from DE19681807447 external-priority patent/DE1807447A1/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of GB1212138A publication Critical patent/GB1212138A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)

Abstract

1,212,138. Injectable asparaginase solutions. FARBENFABRIKEN BAYER A.G. 14 Jan., 1969 [29 May, 1968; 7 Nov., 1968], No. 2169/ 69. Heading A5B. [Also in Division C3] Parenterally injectable solutions of L-asparaginase are stabilised with polyethylene glycol, or with glycine. They may be in dosage unit form in ampoules.
GB216969A 1968-05-29 1969-01-14 Enzyme stabilization Expired GB1212138A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19681767617 DE1767617A1 (en) 1968-05-29 1968-05-29 Method of stabilizing L-asparaginase
DE19681807447 DE1807447A1 (en) 1968-11-07 1968-11-07 Stabilising l-aspanaginase with polyethylene - glycol

Publications (1)

Publication Number Publication Date
GB1212138A true GB1212138A (en) 1970-11-11

Family

ID=25755469

Family Applications (1)

Application Number Title Priority Date Filing Date
GB216969A Expired GB1212138A (en) 1968-05-29 1969-01-14 Enzyme stabilization

Country Status (11)

Country Link
AT (1) AT284757B (en)
BE (1) BE729495A (en)
CH (1) CH528547A (en)
CY (1) CY593A (en)
DK (1) DK121801B (en)
ES (1) ES367709A1 (en)
FI (1) FI46391C (en)
FR (1) FR2009529A1 (en)
GB (1) GB1212138A (en)
MY (1) MY7100163A (en)
NL (1) NL6902079A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104498468A (en) * 2015-01-13 2015-04-08 江南大学 Asparaginase mixture and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806815A (en) * 1955-04-12 1957-09-17 Ortho Pharma Corp Stabilized hyaluronidase
FR1350895A (en) * 1962-01-03 1964-01-31 South African Inventions Precipitation of organic colloids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104498468A (en) * 2015-01-13 2015-04-08 江南大学 Asparaginase mixture and application thereof

Also Published As

Publication number Publication date
CH528547A (en) 1972-09-30
FR2009529A1 (en) 1970-02-06
DK121801B (en) 1971-12-06
FI46391C (en) 1973-03-12
AT284757B (en) 1970-09-25
NL6902079A (en) 1969-12-02
BE729495A (en) 1969-09-08
MY7100163A (en) 1971-12-31
ES367709A1 (en) 1971-07-16
CY593A (en) 1971-06-24
FI46391B (en) 1972-11-30

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees