ES367709A1 - Enzyme stabilization - Google Patents

Enzyme stabilization

Info

Publication number
ES367709A1
ES367709A1 ES367709A ES367709A ES367709A1 ES 367709 A1 ES367709 A1 ES 367709A1 ES 367709 A ES367709 A ES 367709A ES 367709 A ES367709 A ES 367709A ES 367709 A1 ES367709 A1 ES 367709A1
Authority
ES
Spain
Prior art keywords
enzyme stabilization
asparaginase
stabilised
ampoules
glycine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES367709A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681767617 external-priority patent/DE1767617A1/en
Priority claimed from DE19681807447 external-priority patent/DE1807447A1/en
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES367709A1 publication Critical patent/ES367709A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/82—Asparaginase (3.5.1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Parenterally injectable solutions of L-asparaginase are stabilised with polyethylene glycol, or with glycine. They may be in dosage unit form in ampoules.
ES367709A 1968-05-29 1969-05-27 Enzyme stabilization Expired ES367709A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19681767617 DE1767617A1 (en) 1968-05-29 1968-05-29 Method of stabilizing L-asparaginase
DE19681807447 DE1807447A1 (en) 1968-11-07 1968-11-07 Stabilising l-aspanaginase with polyethylene - glycol

Publications (1)

Publication Number Publication Date
ES367709A1 true ES367709A1 (en) 1971-07-16

Family

ID=25755469

Family Applications (1)

Application Number Title Priority Date Filing Date
ES367709A Expired ES367709A1 (en) 1968-05-29 1969-05-27 Enzyme stabilization

Country Status (11)

Country Link
AT (1) AT284757B (en)
BE (1) BE729495A (en)
CH (1) CH528547A (en)
CY (1) CY593A (en)
DK (1) DK121801B (en)
ES (1) ES367709A1 (en)
FI (1) FI46391C (en)
FR (1) FR2009529A1 (en)
GB (1) GB1212138A (en)
MY (1) MY7100163A (en)
NL (1) NL6902079A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104498468A (en) * 2015-01-13 2015-04-08 江南大学 Asparaginase mixture and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806815A (en) * 1955-04-12 1957-09-17 Ortho Pharma Corp Stabilized hyaluronidase
FR1350895A (en) * 1962-01-03 1964-01-31 South African Inventions Precipitation of organic colloids

Also Published As

Publication number Publication date
FI46391B (en) 1972-11-30
MY7100163A (en) 1971-12-31
FI46391C (en) 1973-03-12
CY593A (en) 1971-06-24
AT284757B (en) 1970-09-25
FR2009529A1 (en) 1970-02-06
GB1212138A (en) 1970-11-11
NL6902079A (en) 1969-12-02
CH528547A (en) 1972-09-30
DK121801B (en) 1971-12-06
BE729495A (en) 1969-09-08

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