GB1260963A - Substituted insulins - Google Patents

Substituted insulins

Info

Publication number
GB1260963A
GB1260963A GB537569A GB537569A GB1260963A GB 1260963 A GB1260963 A GB 1260963A GB 537569 A GB537569 A GB 537569A GB 537569 A GB537569 A GB 537569A GB 1260963 A GB1260963 A GB 1260963A
Authority
GB
United Kingdom
Prior art keywords
insulin
carbonyl
substituted insulins
insulins
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB537569A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1260963A publication Critical patent/GB1260963A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions

Abstract

1,260,963. Insulin preparations. AMERICAN HOME PRODUCTS CORP. 31 Jan., 1969 [1 Feb., 1968], No. 5375/69. Heading A5B. [Also in Division C2] Solutions for injection contain 1-aminocyclopentane carbonyl-, 1-aminocyclohexane carbonyl- or L-tryptophanyl-insulin, (i.e. derivatives of insulin wherein from one to twelve of the free amino groups in the insulin molecule are aminoacylated).
GB537569A 1968-02-01 1969-01-31 Substituted insulins Expired GB1260963A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70224568A 1968-02-01 1968-02-01

Publications (1)

Publication Number Publication Date
GB1260963A true GB1260963A (en) 1972-01-19

Family

ID=24820415

Family Applications (1)

Application Number Title Priority Date Filing Date
GB537569A Expired GB1260963A (en) 1968-02-01 1969-01-31 Substituted insulins

Country Status (4)

Country Link
JP (1) JPS4910516B1 (en)
DE (1) DE1902865A1 (en)
FR (1) FR2001142A1 (en)
GB (1) GB1260963A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631347A (en) * 1995-06-07 1997-05-20 Eli Lilly And Company Reducing gelation of a fatty acid-acylated protein
US5646242A (en) * 1994-11-17 1997-07-08 Eli Lilly And Company Selective acylation of epsilon-amino groups
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US5700904A (en) * 1995-06-07 1997-12-23 Eli Lilly And Company Preparation of an acylated protein powder

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50116349U (en) * 1974-03-05 1975-09-22
JPS529420U (en) * 1975-07-08 1977-01-22
JPS5264760U (en) * 1975-11-07 1977-05-13
JPS52135804U (en) * 1976-04-06 1977-10-15
JPS5371414U (en) * 1976-11-17 1978-06-15

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646242A (en) * 1994-11-17 1997-07-08 Eli Lilly And Company Selective acylation of epsilon-amino groups
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US5922675A (en) * 1994-11-17 1999-07-13 Eli Lilly And Company Acylated Insulin Analogs
USRE37971E1 (en) 1994-11-17 2003-01-28 Eli Lilly And Company Selective acylation of epsilon-amino groups
US5631347A (en) * 1995-06-07 1997-05-20 Eli Lilly And Company Reducing gelation of a fatty acid-acylated protein
US5700904A (en) * 1995-06-07 1997-12-23 Eli Lilly And Company Preparation of an acylated protein powder

Also Published As

Publication number Publication date
FR2001142A1 (en) 1969-09-26
DE1902865A1 (en) 1969-09-11
JPS4910516B1 (en) 1974-03-11

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