GB1194183A - Biologically Active Propionamidines and their preparation - Google Patents
Biologically Active Propionamidines and their preparationInfo
- Publication number
- GB1194183A GB1194183A GB27627/66A GB2762766A GB1194183A GB 1194183 A GB1194183 A GB 1194183A GB 27627/66 A GB27627/66 A GB 27627/66A GB 2762766 A GB2762766 A GB 2762766A GB 1194183 A GB1194183 A GB 1194183A
- Authority
- GB
- United Kingdom
- Prior art keywords
- propionamidines
- prepared
- methoxyphenoxy
- chlorophenoxy
- june
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GNFWGDKKNWGGJY-UHFFFAOYSA-N propanimidamide Chemical class CCC(N)=N GNFWGDKKNWGGJY-UHFFFAOYSA-N 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- -1 alkali metal amide Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- WTDHULULXKLSOZ-UHFFFAOYSA-N Hydroxylamine hydrochloride Chemical compound Cl.ON WTDHULULXKLSOZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- WPZSAUFQHYFIPG-UHFFFAOYSA-N propanethioamide Chemical class CCC(N)=S WPZSAUFQHYFIPG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- OEWPDZVHFDWAIH-UHFFFAOYSA-N 2-(3-chlorophenoxy)propanenitrile Chemical compound N#CC(C)OC1=CC=CC(Cl)=C1 OEWPDZVHFDWAIH-UHFFFAOYSA-N 0.000 abstract 1
- ABYGZZIGDUNFGL-UHFFFAOYSA-N 2-(3-chlorophenoxy)propanethioamide Chemical compound NC(=S)C(C)OC1=CC=CC(Cl)=C1 ABYGZZIGDUNFGL-UHFFFAOYSA-N 0.000 abstract 1
- BMPGGDBVJBYPRA-UHFFFAOYSA-N 2-(3-methoxyphenoxy)propanenitrile Chemical compound COC1=CC=CC(OC(C)C#N)=C1 BMPGGDBVJBYPRA-UHFFFAOYSA-N 0.000 abstract 1
- JNAYPRPPXRWGQO-UHFFFAOYSA-N 2-chloropropanenitrile Chemical compound CC(Cl)C#N JNAYPRPPXRWGQO-UHFFFAOYSA-N 0.000 abstract 1
- SSJVMRKIOZHZDX-UHFFFAOYSA-N Cl.COC=1C=C(OC(C(N)=NO)C)C=CC1 Chemical compound Cl.COC=1C=C(OC(C(N)=NO)C)C=CC1 SSJVMRKIOZHZDX-UHFFFAOYSA-N 0.000 abstract 1
- RCKYYKZMELQKRT-UHFFFAOYSA-N I.ClC=1C=C(OC(C(SC)=N)C)C=CC1 Chemical compound I.ClC=1C=C(OC(C(SC)=N)C)C=CC1 RCKYYKZMELQKRT-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000003943 catecholamines Chemical class 0.000 abstract 1
- RLZPCFQNZGINRP-UHFFFAOYSA-N n'-hydroxypropanimidamide Chemical class CCC(N)=NO RLZPCFQNZGINRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB27627/66A GB1194183A (en) | 1966-06-21 | 1966-06-21 | Biologically Active Propionamidines and their preparation |
| GR670134158A GR34158B (el) | 1966-06-21 | 1967-06-06 | Μεθοδος παρασκευης βιολογικως ενεργων αμιδινων. |
| CA992,470A CA939385A (en) | 1966-06-21 | 1967-06-07 | Biologically active amidines and their preparation |
| IL28120A IL28120A (en) | 1966-06-21 | 1967-06-09 | Propioamidines,their preparations,and pharmaceutical compositions containing them |
| CH69870A CH507212A (de) | 1966-06-21 | 1967-06-15 | Verfahren zur Herstellung von Propionamidinen |
| CH849767A CH509273A (de) | 1966-06-21 | 1967-06-15 | Verfahren zur Herstellung von Propionamidinen |
| CH69970A CH489477A (de) | 1966-06-21 | 1967-06-15 | Verfahren zur Herstellung von Propionamidinen |
| CH69770A CH521319A (de) | 1966-06-21 | 1967-06-15 | Verfahren zur Herstellung von Propionamidinen |
| BE700096D BE700096A (en:Method) | 1966-06-21 | 1967-06-16 | |
| AT560067A AT291220B (de) | 1966-06-21 | 1967-06-16 | Verfahren zur Herstellung von neuen Propionamidinen oder deren Säureadditionssalzen |
| SE08607/67A SE339468B (en:Method) | 1966-06-21 | 1967-06-19 | |
| DK316667AA DK126376B (da) | 1966-06-21 | 1967-06-19 | Analogifremgangsmåde til fremstilling af amidiner eller syreadditionssalte deraf. |
| ES342072A ES342072A1 (es) | 1966-06-21 | 1967-06-20 | Un metodo para preparar una propionamidina. |
| DE19671643216 DE1643216A1 (de) | 1966-06-21 | 1967-06-20 | Biologisch aktive Amidine und ihre Herstellung |
| LU53925D LU53925A1 (en:Method) | 1966-06-21 | 1967-06-20 | |
| FI671731A FI48461C (fi) | 1966-06-21 | 1967-06-20 | Menetelmä terapeuttisesti arvokkaan propioniamidiinin sekä sen happoad ditiosuolan valmistamiseksi. |
| NL6708561A NL6708561A (en:Method) | 1966-06-21 | 1967-06-20 | |
| NO168663A NO120145B (en:Method) | 1966-06-21 | 1967-06-20 | |
| JP42039388A JPS4927859B1 (en:Method) | 1966-06-21 | 1967-06-21 | |
| FR1572961D FR1572961A (en:Method) | 1966-06-21 | 1967-06-21 | |
| CS4552A CS177802B2 (en:Method) | 1966-06-21 | 1967-06-21 | |
| FR121436A FR6910M (en:Method) | 1966-06-21 | 1967-09-19 | |
| JP45046452A JPS4933941B1 (en:Method) | 1966-06-21 | 1970-06-01 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB27627/66A GB1194183A (en) | 1966-06-21 | 1966-06-21 | Biologically Active Propionamidines and their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1194183A true GB1194183A (en) | 1970-06-10 |
Family
ID=10262684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB27627/66A Expired GB1194183A (en) | 1966-06-21 | 1966-06-21 | Biologically Active Propionamidines and their preparation |
Country Status (18)
| Country | Link |
|---|---|
| JP (2) | JPS4927859B1 (en:Method) |
| AT (1) | AT291220B (en:Method) |
| BE (1) | BE700096A (en:Method) |
| CA (1) | CA939385A (en:Method) |
| CH (1) | CH509273A (en:Method) |
| CS (1) | CS177802B2 (en:Method) |
| DE (1) | DE1643216A1 (en:Method) |
| DK (1) | DK126376B (en:Method) |
| ES (1) | ES342072A1 (en:Method) |
| FI (1) | FI48461C (en:Method) |
| FR (2) | FR1572961A (en:Method) |
| GB (1) | GB1194183A (en:Method) |
| GR (1) | GR34158B (en:Method) |
| IL (1) | IL28120A (en:Method) |
| LU (1) | LU53925A1 (en:Method) |
| NL (1) | NL6708561A (en:Method) |
| NO (1) | NO120145B (en:Method) |
| SE (1) | SE339468B (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53144676U (en:Method) * | 1977-04-21 | 1978-11-15 |
-
1966
- 1966-06-21 GB GB27627/66A patent/GB1194183A/en not_active Expired
-
1967
- 1967-06-06 GR GR670134158A patent/GR34158B/el unknown
- 1967-06-07 CA CA992,470A patent/CA939385A/en not_active Expired
- 1967-06-09 IL IL28120A patent/IL28120A/xx unknown
- 1967-06-15 CH CH849767A patent/CH509273A/de not_active IP Right Cessation
- 1967-06-16 AT AT560067A patent/AT291220B/de not_active IP Right Cessation
- 1967-06-16 BE BE700096D patent/BE700096A/xx unknown
- 1967-06-19 DK DK316667AA patent/DK126376B/da unknown
- 1967-06-19 SE SE08607/67A patent/SE339468B/xx unknown
- 1967-06-20 NL NL6708561A patent/NL6708561A/xx unknown
- 1967-06-20 FI FI671731A patent/FI48461C/fi active
- 1967-06-20 LU LU53925D patent/LU53925A1/xx unknown
- 1967-06-20 DE DE19671643216 patent/DE1643216A1/de active Pending
- 1967-06-20 NO NO168663A patent/NO120145B/no unknown
- 1967-06-20 ES ES342072A patent/ES342072A1/es not_active Expired
- 1967-06-21 JP JP42039388A patent/JPS4927859B1/ja active Pending
- 1967-06-21 CS CS4552A patent/CS177802B2/cs unknown
- 1967-06-21 FR FR1572961D patent/FR1572961A/fr not_active Expired
- 1967-09-19 FR FR121436A patent/FR6910M/fr not_active Expired
-
1970
- 1970-06-01 JP JP45046452A patent/JPS4933941B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL6708561A (en:Method) | 1967-12-22 |
| DE1643216A1 (de) | 1971-07-29 |
| JPS4927859B1 (en:Method) | 1974-07-22 |
| ES342072A1 (es) | 1968-07-16 |
| FR1572961A (en:Method) | 1969-07-04 |
| FR6910M (en:Method) | 1969-04-28 |
| DK126376B (da) | 1973-07-09 |
| CA939385A (en) | 1974-01-01 |
| AT291220B (de) | 1971-07-12 |
| IL28120A (en) | 1971-03-24 |
| CS177802B2 (en:Method) | 1977-08-31 |
| GR34158B (el) | 1968-03-30 |
| CH509273A (de) | 1971-06-30 |
| FI48461C (fi) | 1974-10-10 |
| LU53925A1 (en:Method) | 1968-03-11 |
| JPS4933941B1 (en:Method) | 1974-09-11 |
| SE339468B (en:Method) | 1971-10-11 |
| NO120145B (en:Method) | 1970-09-07 |
| FI48461B (en:Method) | 1974-07-01 |
| BE700096A (en:Method) | 1967-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1114069A (en) | Benzimidazole derivatives and anthelmintic compositions containing them | |
| KR880002840A (ko) | 이미다졸 화합물, 그의 제조 방법 및 이것으로 되는 제약 조성물 | |
| GB1309835A (en) | Trialkoxy-quinazolines | |
| ES8102101A1 (es) | Procedimiento para preparar derivados de pirimidina | |
| GB1327312A (en) | Hererocyclic compounds | |
| ES356131A1 (es) | Procedimiento de preparacion de nuevas amidinas aromaticas n-sustituidas. | |
| GB1142066A (en) | New diphenyl-ureas and process for preparing them | |
| GB1194183A (en) | Biologically Active Propionamidines and their preparation | |
| GB1169945A (en) | Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives | |
| GB1309358A (en) | Thionothiolphosphoric acid ester amides a process for their preparation and their use as nematocides insecticides and acaricides | |
| GB1203430A (en) | Heterocyclic spiro compounds | |
| GB1433916A (en) | Thiophosphoric acid amides as nematocides insecticides and acaricides | |
| GB1162247A (en) | Cephalosporanic Acid Derivatives and a Process for the Preparation thereof | |
| GB1365441A (en) | Derivatives of 3-formyl-2-quinoxaline-carboxamide-1 4-dioxides their production and their medicinal and veterinary use | |
| GB1292417A (en) | 4-amino-2-(5-nitro-2-thienyl) quinazolines, their preparation, and compositions containing them | |
| GB842325A (en) | Pharmaceutical compositions containing aminoguanidine derivatives | |
| GB1082943A (en) | Derivatives of 7-aminocephalosporanic acid | |
| GB1311618A (en) | 4-sulphanilyl phenyl urea complexes | |
| GB1480892A (en) | 3-nitropyrazole derivatives | |
| GB1321368A (en) | Organo-phosphorus compounds useful for the control of helminths in warm-blooded animals | |
| GB1530166A (en) | Adenine derivatives | |
| GB1353665A (en) | Thiocyanic acid esters and process for their preparation | |
| GB1311334A (en) | 2-substituted aminohexahydrobenzo alpha-quinolizines | |
| GB1280551A (en) | Quinazoline derivatives | |
| GB1307978A (en) | Amidines processes for their preparation and pharmaceutical compo sitions incorporating the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |