GB1187114A - Processes for the Preparation of Delta1,3,5(10),6,8 and Delta1,3,5,(10),8,14 Steroid Compounds - Google Patents

Processes for the Preparation of Delta1,3,5(10),6,8 and Delta1,3,5,(10),8,14 Steroid Compounds

Info

Publication number
GB1187114A
GB1187114A GB1609367A GB1609367A GB1187114A GB 1187114 A GB1187114 A GB 1187114A GB 1609367 A GB1609367 A GB 1609367A GB 1609367 A GB1609367 A GB 1609367A GB 1187114 A GB1187114 A GB 1187114A
Authority
GB
United Kingdom
Prior art keywords
delta1
april
steroids
agents
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1609367A
Inventor
H Smith
R C Smith
R P Stein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1187114A publication Critical patent/GB1187114A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

1,187,114. Medicines comprising steroids. AMERICAN HOME PRODUCTS CORP. 7 April, 1967 [7 April, 1966; 25 April, 1966; 12 Aug., 1966; 21 Jan., 1967], No. 16093/67. Heading A5B. [Also in Division C2] Pharmaceutical compositions comprise steroids of the formula: (where R' is C 1-6 alkyl; R is H, OH, C 1-6 etherified OH, C 1-6 alkyl, or C 1-6 alkanoyloxy; and X is CO or CHOH) in d-, l- or dlform and carriers. The steroids have estrogenic activity. The compositions may be liquid or solid and may contain diluents, flavouring agents, solubilizers, lubricants, suspending agents, binders, tablet-disintegrating agents and surface-active agents.
GB1609367A 1966-04-07 1967-04-07 Processes for the Preparation of Delta1,3,5(10),6,8 and Delta1,3,5,(10),8,14 Steroid Compounds Expired GB1187114A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US54085766A 1966-04-07 1966-04-07
US54468266A 1966-04-25 1966-04-25
US57198266A 1966-08-12 1966-08-12
GB267967 1967-01-18
US64791067A 1967-06-22 1967-06-22

Publications (1)

Publication Number Publication Date
GB1187114A true GB1187114A (en) 1970-04-08

Family

ID=27515705

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1609367A Expired GB1187114A (en) 1966-04-07 1967-04-07 Processes for the Preparation of Delta1,3,5(10),6,8 and Delta1,3,5,(10),8,14 Steroid Compounds

Country Status (2)

Country Link
DE (1) DE1618053B1 (en)
GB (1) GB1187114A (en)

Also Published As

Publication number Publication date
DE1618053B1 (en) 1971-12-16

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Legal Events

Date Code Title Description
PS Patent sealed
429A Application made for amendment of specification (sect. 29/1949)
429H Application (made) for amendment of specification now open to opposition (sect. 29/1949)
429D Case decided by the comptroller ** specification amended (sect. 29/1949)
PE Patent expired