GB1171434A - Novel Barbituric Acid Derivatives and a Process for the Manufacture thereof - Google Patents

Novel Barbituric Acid Derivatives and a Process for the Manufacture thereof

Info

Publication number
GB1171434A
GB1171434A GB9203/68A GB920368A GB1171434A GB 1171434 A GB1171434 A GB 1171434A GB 9203/68 A GB9203/68 A GB 9203/68A GB 920368 A GB920368 A GB 920368A GB 1171434 A GB1171434 A GB 1171434A
Authority
GB
United Kingdom
Prior art keywords
barbituric acid
manufacture
acid derivatives
feb
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9203/68A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1171434A publication Critical patent/GB1171434A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB9203/68A 1967-02-27 1968-02-26 Novel Barbituric Acid Derivatives and a Process for the Manufacture thereof Expired GB1171434A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61903067A 1967-02-27 1967-02-27

Publications (1)

Publication Number Publication Date
GB1171434A true GB1171434A (en) 1969-11-19

Family

ID=24480165

Family Applications (2)

Application Number Title Priority Date Filing Date
GB9203/68A Expired GB1171434A (en) 1967-02-27 1968-02-26 Novel Barbituric Acid Derivatives and a Process for the Manufacture thereof
GB5177/69A Expired GB1171435A (en) 1967-02-27 1968-02-26 Novel Malonates

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB5177/69A Expired GB1171435A (en) 1967-02-27 1968-02-26 Novel Malonates

Country Status (6)

Country Link
US (1) US3464990A (cg-RX-API-DMAC7.html)
BE (1) BE711354A (cg-RX-API-DMAC7.html)
ES (1) ES350955A1 (cg-RX-API-DMAC7.html)
FR (2) FR7350M (cg-RX-API-DMAC7.html)
GB (2) GB1171434A (cg-RX-API-DMAC7.html)
NL (1) NL6802736A (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016315A1 (en) * 1990-04-12 1991-10-31 Brown University Research Foundation 5-benzyl barbiturate derivatives

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE28377E (en) * 1970-11-09 1975-03-25 Selected s.substituted-s-phenylalkyl barbituric acids
CH570438A5 (cg-RX-API-DMAC7.html) * 1972-05-04 1975-12-15 Ciba Geigy Ag
FR2283129A1 (fr) * 1974-03-01 1976-03-26 Wellcome Found Procede de preparation d'un derive de pyrimidine et nouveau produit ainsi obtenu
EP0223037A1 (de) * 1985-10-24 1987-05-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenylbarbitursäuren und deren Herstellung

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991016315A1 (en) * 1990-04-12 1991-10-31 Brown University Research Foundation 5-benzyl barbiturate derivatives
US5141943A (en) * 1990-04-12 1992-08-25 Brown University Research Foundation 5-benzyl barbiturate derivatives
JP3001972B2 (ja) 1990-04-12 2000-01-24 ブラウン ユニバーシティ リサーチ ファウンディション ５―ベンジルバルビツレート誘導体

Also Published As

Publication number Publication date
ES350955A1 (es) 1969-05-16
FR7350M (cg-RX-API-DMAC7.html) 1969-10-13
NL6802736A (cg-RX-API-DMAC7.html) 1968-08-28
US3464990A (en) 1969-09-02
GB1171435A (en) 1969-11-19
FR1563925A (cg-RX-API-DMAC7.html) 1969-04-18
BE711354A (cg-RX-API-DMAC7.html) 1968-08-27

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