GB1159970A - The Antibiotic Steffisburgensimycin - Google Patents
The Antibiotic SteffisburgensimycinInfo
- Publication number
- GB1159970A GB1159970A GB55535/66A GB5553566A GB1159970A GB 1159970 A GB1159970 A GB 1159970A GB 55535/66 A GB55535/66 A GB 55535/66A GB 5553566 A GB5553566 A GB 5553566A GB 1159970 A GB1159970 A GB 1159970A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antibiotic
- steffisburgensimycin
- methanol
- isopropanol
- dec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 5
- HWMJTJZEJBSVCG-UHFFFAOYSA-N 4-(4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-3,4-dihydrotetracene-1,6,11-trione Chemical compound COC1C(O)C(O)C(C)OC1OC1C2=C(O)C(C(=O)C3=C(O)C=C(OC)C=C3C3=O)=C3C=C2C(=O)C(C)(O)C1OC HWMJTJZEJBSVCG-UHFFFAOYSA-N 0.000 title abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 9
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- ZYECOAILUNWEAL-NUDFZHEQSA-N (4z)-4-[[2-methoxy-5-(phenylcarbamoyl)phenyl]hydrazinylidene]-n-(3-nitrophenyl)-3-oxonaphthalene-2-carboxamide Chemical compound COC1=CC=C(C(=O)NC=2C=CC=CC=2)C=C1N\N=C(C1=CC=CC=C1C=1)/C(=O)C=1C(=O)NC1=CC=CC([N+]([O-])=O)=C1 ZYECOAILUNWEAL-NUDFZHEQSA-N 0.000 abstract 1
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000970876 Streptomyces steffisburgensis Species 0.000 abstract 1
- 238000000862 absorption spectrum Methods 0.000 abstract 1
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 239000000645 desinfectant Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000006052 feed supplement Substances 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 238000000622 liquid--liquid extraction Methods 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000003209 petroleum derivative Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G11/00—Antibiotics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US527634A US3309273A (en) | 1965-12-29 | 1965-12-29 | Antibiotic steffisburgensimycin and method of producing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1159970A true GB1159970A (en) | 1969-07-30 |
Family
ID=24102307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB55535/66A Expired GB1159970A (en) | 1965-12-29 | 1966-12-12 | The Antibiotic Steffisburgensimycin |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3309273A (enExample) |
| DE (1) | DE1617910A1 (enExample) |
| FR (2) | FR1506218A (enExample) |
| GB (1) | GB1159970A (enExample) |
| NL (1) | NL151737B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3794721A (en) * | 1972-08-28 | 1974-02-26 | Upjohn Co | Antibiotic steffimycin b and process for the preparation thereof |
| US4209611A (en) * | 1979-04-06 | 1980-06-24 | The Upjohn Company | Dihydrosteffimycin compounds |
| US4264726A (en) * | 1979-04-06 | 1981-04-28 | The Upjohn Company | Process for producing 10═dihydrosteffimycin and 10═dihydrosteffimycin B and microorganisms for producing same |
| JP7184260B2 (ja) | 2017-09-01 | 2022-12-06 | 学校法人北里研究所 | マイコバクテリウム・アビウム複合感染症に対する治療活性を有する新規化合物及びその製造方法 |
-
1965
- 1965-12-29 US US527634A patent/US3309273A/en not_active Expired - Lifetime
-
1966
- 1966-12-12 GB GB55535/66A patent/GB1159970A/en not_active Expired
- 1966-12-24 DE DE19661617910 patent/DE1617910A1/de active Pending
- 1966-12-28 FR FR89175A patent/FR1506218A/fr not_active Expired
- 1966-12-29 NL NL666618321A patent/NL151737B/xx unknown
-
1967
- 1967-03-24 FR FR100239A patent/FR6186M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR6186M (enExample) | 1968-07-15 |
| FR1506218A (fr) | 1967-12-15 |
| US3309273A (en) | 1967-03-14 |
| NL151737B (nl) | 1976-12-15 |
| DE1617910A1 (de) | 1971-04-01 |
| NL6618321A (enExample) | 1967-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |