GB1159695A - Fermentative Production of Griseofulvin. - Google Patents
Fermentative Production of Griseofulvin.Info
- Publication number
- GB1159695A GB1159695A GB4254966A GB4254966A GB1159695A GB 1159695 A GB1159695 A GB 1159695A GB 4254966 A GB4254966 A GB 4254966A GB 4254966 A GB4254966 A GB 4254966A GB 1159695 A GB1159695 A GB 1159695A
- Authority
- GB
- United Kingdom
- Prior art keywords
- griseofulvin
- fermentation
- air
- trays
- penicillium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 title abstract 4
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 title abstract 4
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 title abstract 4
- DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 title abstract 4
- 229960002867 griseofulvin Drugs 0.000 title abstract 4
- 238000012262 fermentative production Methods 0.000 title 1
- 238000000855 fermentation Methods 0.000 abstract 6
- 230000004151 fermentation Effects 0.000 abstract 6
- 241000233866 Fungi Species 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 241001149507 Penicillium urticae Species 0.000 abstract 2
- 241000228127 Penicillium griseofulvum Species 0.000 abstract 1
- 241000519895 Penicillium janczewskii Species 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000001427 coherent effect Effects 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/04—Flat or tray type, drawers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/38—Caps; Covers; Plugs; Pouring means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/22—Perforated plates, discs or walls
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/24—Recirculation of gas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT874065A AT264006B (de) | 1965-09-24 | 1965-09-24 | Verfahren zur Herstellung von Griseofulvin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1159695A true GB1159695A (en) | 1969-07-30 |
Family
ID=3608135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4254966A Expired GB1159695A (en) | 1965-09-24 | 1966-09-23 | Fermentative Production of Griseofulvin. |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT264006B (enrdf_load_html_response) |
| CH (1) | CH482019A (enrdf_load_html_response) |
| DE (1) | DE1617329A1 (enrdf_load_html_response) |
| DK (1) | DK119201B (enrdf_load_html_response) |
| GB (1) | GB1159695A (enrdf_load_html_response) |
| NL (1) | NL6613178A (enrdf_load_html_response) |
| SE (1) | SE352654B (enrdf_load_html_response) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108823110A (zh) * | 2018-07-26 | 2018-11-16 | 福州工微生物科技有限公司 | 一株产灰黄霉素的菌株及其应用 |
| CN108841733A (zh) * | 2018-07-26 | 2018-11-20 | 福州工微生物科技有限公司 | 一株生产松刚霉素主份——灰黄霉素的菌株及方法 |
| CN108841889A (zh) * | 2018-07-26 | 2018-11-20 | 福州工微生物科技有限公司 | 利用微生物发酵生产松刚霉素主份——灰黄霉素的方法 |
-
1965
- 1965-09-24 AT AT874065A patent/AT264006B/de active
-
1966
- 1966-07-27 CH CH1085266A patent/CH482019A/de not_active IP Right Cessation
- 1966-09-19 NL NL6613178A patent/NL6613178A/xx unknown
- 1966-09-21 DE DE19661617329 patent/DE1617329A1/de active Pending
- 1966-09-23 GB GB4254966A patent/GB1159695A/en not_active Expired
- 1966-09-23 DK DK495666A patent/DK119201B/da unknown
- 1966-09-23 SE SE1283366A patent/SE352654B/xx unknown
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108823110A (zh) * | 2018-07-26 | 2018-11-16 | 福州工微生物科技有限公司 | 一株产灰黄霉素的菌株及其应用 |
| CN108841733A (zh) * | 2018-07-26 | 2018-11-20 | 福州工微生物科技有限公司 | 一株生产松刚霉素主份——灰黄霉素的菌株及方法 |
| CN108841889A (zh) * | 2018-07-26 | 2018-11-20 | 福州工微生物科技有限公司 | 利用微生物发酵生产松刚霉素主份——灰黄霉素的方法 |
| CN108823110B (zh) * | 2018-07-26 | 2021-07-16 | 福州工微生物科技有限公司 | 一株产灰黄霉素的菌株及其应用 |
| CN108841733B (zh) * | 2018-07-26 | 2021-09-28 | 福州工微生物科技有限公司 | 一株生产松刚霉素主份——灰黄霉素的菌株及方法 |
| CN108841889B (zh) * | 2018-07-26 | 2021-09-28 | 福州工微生物科技有限公司 | 利用微生物发酵生产松刚霉素主份——灰黄霉素的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| NL6613178A (enrdf_load_html_response) | 1967-03-28 |
| CH482019A (de) | 1969-11-30 |
| SE352654B (enrdf_load_html_response) | 1973-01-08 |
| DK119201B (da) | 1970-11-30 |
| DE1617329A1 (de) | 1971-04-22 |
| AT264006B (de) | 1968-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 416 | Proceeding under section 16 patents act 1949 | ||
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |