GB1159626A - Indole Derivatives - Google Patents

Indole Derivatives

Info

Publication number
GB1159626A
GB1159626A GB3764567A GB3764567A GB1159626A GB 1159626 A GB1159626 A GB 1159626A GB 3764567 A GB3764567 A GB 3764567A GB 3764567 A GB3764567 A GB 3764567A GB 1159626 A GB1159626 A GB 1159626A
Authority
GB
United Kingdom
Prior art keywords
general formula
indole derivatives
aug
indole
hydrochloric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3764567A
Inventor
John Martin Chemerda
Meyer Sletzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1159626A publication Critical patent/GB1159626A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,159,626. Indole derivatives. MERCK & CO. Inc. 16 Aug., 1967 [25 Aug., 1966], No. 37645/67. Heading C2C. Indole derivatives of the general formula wherein R is a methoxy or dimethylamino group, are prepared by reduction of an indole derivative of the general formula conversion of the resulting novel indole derivative of the general formula to a corresponding diazonium salt, e.g. by means of dilute hydrochloric acid and aqueous sodium nitrite, followed by replacement of the diazonium group by a chlorine atom, e.g. by treatment with cuprous chloride, copper powder or copperbronze powder and hydrochloric acid.
GB3764567A 1966-08-25 1967-08-16 Indole Derivatives Expired GB1159626A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA968825 1966-08-25

Publications (1)

Publication Number Publication Date
GB1159626A true GB1159626A (en) 1969-07-30

Family

ID=4142647

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3764567A Expired GB1159626A (en) 1966-08-25 1967-08-16 Indole Derivatives

Country Status (4)

Country Link
CH (1) CH487150A (en)
DE (1) DE1695469A1 (en)
GB (1) GB1159626A (en)
NL (1) NL6711395A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013060A1 (en) * 1990-02-26 1991-09-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5283251A (en) * 1990-02-26 1994-02-01 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013060A1 (en) * 1990-02-26 1991-09-05 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives
US5283251A (en) * 1990-02-26 1994-02-01 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives

Also Published As

Publication number Publication date
DE1695469A1 (en) 1971-04-15
NL6711395A (en) 1968-02-26
CH487150A (en) 1970-03-15

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees